AutismKB 2.0

Annotation Detail for DAGLB


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Basic Information Top
Gene Symbol:DAGLB ( DAGLBETA,FLJ33624,FLJ33909,FLJ45532,KCCR13L )
Gene Full Name: diacylglycerol lipase, beta
Band: 7p22.1
Quick LinksEntrez ID:221955; OMIM: NA; Uniprot ID:DGLB_HUMAN; ENSEMBL ID: ENSG00000164535; HGNC ID: 28923
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus61 / 564012108
neonate5 / 31097160
infant3 / 23620127
juvenile6 / 55556107
adult115 / 193912159
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor3 / 3436687
chondrosarcoma4 / 8282348
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor40 / 263845151
glioma16 / 106883149
head and neck tumor19 / 136302139
kidney tumor1 / 6895914
leukemia8 / 9584283
liver tumor7 / 9635972
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia6 / 9725061
normal263 / 336030778
ovarian tumor2 / 7668226
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS12 / 12568095
prostate cancer5 / 10268048
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites2 / 4001549
bladder0 / 297570 
blood7 / 12347856
bone4 / 7165555
bone marrow7 / 48801143
brain127 / 1100989115
cervix4 / 4817183
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye8 / 21105437
heart2 / 8962622
intestine8 / 23447234
kidney16 / 21177775
larynx0 / 241450 
liver13 / 20774362
lung21 / 33697462
lymph0 / 442700 
lymph node20 / 91610218
mammary gland7 / 15327145
mouth18 / 67052268
muscle5 / 10771546
nerve1 / 1576863
ovary5 / 10205148
pancreas4 / 21481218
parathyroid4 / 20539194
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta15 / 28082553
prostate11 / 18934558
salivary gland0 / 201550 
skin10 / 21057447
spleen6 / 53952111
stomach6 / 9661962
testis26 / 33044278
thymus18 / 81131221
thyroid4 / 4747384
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord0 / 136800 
uterus9 / 23287838
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P8539
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.67 ± 0.65
Basal Forebrain3.34 ± 0.44
Basal Part of Pons4.04 ± 0.62
Cerebellar Cortex4.11 ± 0.49
Cerebellar Nuclei3.58 ± 0.61
Claustrum3.41 ± 1
Epithalamus3.62 ± 0.67
Frontal Lobe3.88 ± 0.57
Globus Pallidus2.31 ± 0.61
Hypothalamus3.9 ± 0.51
Insula4.02 ± 0.39
Limbic Lobe3.68 ± 0.76
Mesencephalon3.64 ± 0.77
Myelencephalon3.73 ± 0.7
Occipital Lobe3.15 ± 0.81
Parietal Lobe3.74 ± 0.68
Pontine Tegmentum3.62 ± 0.61
Striatum2.88 ± 0.8
Subthalamus3.58 ± 0.78
Temporal Lobe4.08 ± 0.53
Thalamus3.52 ± 0.63
White Matter3.2 ± 0.4
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
E330036I19RikCBCerebellum0
0
E330036I19RikCTXCerebral cortex0
0
E330036I19RikHIPHippocampal region0
0
E330036I19RikHPFHippocampal formation0
0
E330036I19RikHYHypothalamus0
0
E330036I19RikLSXLateral septal complex0
0
E330036I19RikMBMidbrain0
0
E330036I19RikMYMedulla0
0
E330036I19RikOLFOlfactory bulb0
0
E330036I19RikPPons0
0
E330036I19RikPALPallidum0
0
E330036I19RikRHPRetrohippocampal region0
0
E330036I19RiksAMYStriatum-like amygdalar nuclei0
0
E330036I19RikSTRStriatum0
0
E330036I19RikSTRdStriatum dorsal region0
0
E330036I19RikSTRvStriatum ventral region0
0
E330036I19RikTHThalamus0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00536684 18 569 586 WSPAYSFSSDSPLDSSPK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018