AutismKB 2.0

Annotation Detail for FDFT1


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Basic Information Top
Gene Symbol:FDFT1 ( DGPT,ERG9,SQS,SS )
Gene Full Name: farnesyl-diphosphate farnesyltransferase 1
Band: 8p23.1
Quick LinksEntrez ID:2222; OMIM: 184420; Uniprot ID:FDFT_HUMAN; ENSEMBL ID: ENSG00000079459; HGNC ID: 3629
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body20 / 70761282
blastocyst18 / 62319288
fetus162 / 564012287
neonate6 / 31097192
infant18 / 23620762
juvenile48 / 55556863
adult538 / 1939121277
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor6 / 12794468
bladder carcinoma7 / 17475400
breast (mammary gland) tumor17 / 94178180
cervical tumor7 / 34366203
chondrosarcoma14 / 82823169
colorectal tumor52 / 114246455
esophageal tumor2 / 17290115
gastrointestinal tumor31 / 119369259
germ cell tumor81 / 263845306
glioma18 / 106883168
head and neck tumor38 / 136302278
kidney tumor7 / 68959101
leukemia79 / 95842824
liver tumor20 / 96359207
lung tumor29 / 103127281
lymphoma35 / 71755487
non-neoplasia22 / 97250226
normal798 / 3360307237
ovarian tumor22 / 76682286
pancreatic tumor27 / 104616258
primitive neuroectodermal tumor of the CNS43 / 125680342
prostate cancer24 / 102680233
retinoblastoma7 / 46356151
skin tumor61 / 124949488
soft tissue/muscle tissue tumor23 / 125191183
uterine tumor48 / 90257531
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland15 / 33197451
ascites10 / 40015249
bladder18 / 29757604
blood88 / 123478712
bone12 / 71655167
bone marrow13 / 48801266
brain305 / 1100989277
cervix7 / 48171145
connective tissue17 / 149255113
ear5 / 16212308
embryonic tissue69 / 215722319
esophagus2 / 2020998
eye49 / 211054232
heart18 / 89626200
intestine92 / 234472392
kidney23 / 211777108
larynx4 / 24145165
liver40 / 207743192
lung87 / 336974258
lymph13 / 44270293
lymph node16 / 91610174
mammary gland26 / 153271169
mouth11 / 67052164
muscle23 / 107715213
nerve1 / 1576863
ovary37 / 102051362
pancreas36 / 214812167
parathyroid2 / 2053997
pharynx13 / 41328314
pituitary gland0 / 165850 
placenta90 / 280825320
prostate40 / 189345211
salivary gland11 / 20155545
skin90 / 210574427
spleen17 / 53952315
stomach20 / 96619206
testis98 / 330442296
thymus13 / 81131160
thyroid25 / 47473526
tonsil1 / 1699958
trachea6 / 52413114
umbilical cord4 / 13680292
uterus73 / 232878313
vascular7 / 51780135
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208647_at
Cell line Expression level Expression bar
721_B_lymphoblasts1599.4
Adipocyte213.55
AdrenalCortex439
Adrenalgland299.25
Amygdala457.35
Appendix9.95
AtrioventricularNode17.9
BDCA4+_DentriticCells462.65
Bonemarrow159.4
BronchialEpithelialCells2730.9
CD105+_Endothelial279.9
CD14+_Monocytes383.3
CD19+_BCells(neg._sel.)855.15
CD33+_Myeloid439.05
CD34+724.95
CD4+_Tcells358.9
CD56+_NKCells734.75
CD71+_EarlyErythroid537.05
CD8+_Tcells321.25
CardiacMyocytes24.75
Caudatenucleus126.25
Cerebellum101.75
CerebellumPeduncles141.2
CiliaryGanglion25.8
CingulateCortex185.9
Colorectaladenocarcinoma198.4
DorsalRootGanglion67.75
FetalThyroid97.9
Fetalbrain373.7
Fetalliver399.6
Fetallung373.9
GlobusPallidus125.05
Heart148.05
Hypothalamus581.2
Kidney81.25
Leukemia_chronicMyelogenousK-5621233.45
Leukemia_promyelocytic-HL-60814.2
Leukemialymphoblastic(MOLT-4)1522.5
Liver186.85
Lung490.05
Lymphnode90.05
Lymphoma_burkitts(Daudi)750.85
Lymphoma_burkitts(Raji)544.2
MedullaOblongata156.7
OccipitalLobe314.45
OlfactoryBulb313.7
Ovary29.45
Pancreas112.35
PancreaticIslet225.95
ParietalLobe253.6
Pituitary145.6
Placenta221.5
Pons85.05
PrefrontalCortex600.05
Prostate620.5
Salivarygland100.6
SkeletalMuscle10.6
Skin84.4
SmoothMuscle155
Spinalcord515.2
SubthalamicNucleus117.55
SuperiorCervicalGanglion38.7
TemporalLobe173.4
Testis652.05
TestisGermCell519.8
TestisIntersitial326.55
TestisLeydigCell200.7
TestisSeminiferousTubule287.3
Thalamus228.45
Thymus201.65
Thyroid283.8
Tongue157.5
Tonsil161.05
Trachea139.45
TrigeminalGanglion38.6
Uterus190.95
UterusCorpus35.2
WholeBlood207.5
Wholebrain514.4
colon579
pineal_day401.28
pineal_night431.64
retina762.175
small_intestine518.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14679_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.47 ± 0.48
Basal Forebrain8.13 ± 0.38
Basal Part of Pons8.49 ± 0.14
Cerebellar Cortex8.22 ± 0.22
Cerebellar Nuclei8.68 ± 0.33
Claustrum9 ± 0.36
Epithalamus8.21 ± 0.4
Frontal Lobe8.59 ± 0.26
Globus Pallidus8.26 ± 0.44
Hypothalamus8.65 ± 0.3
Insula8.48 ± 0.21
Limbic Lobe8.46 ± 0.37
Mesencephalon8.42 ± 0.4
Myelencephalon8.44 ± 0.41
Occipital Lobe8.1 ± 0.34
Parietal Lobe8.39 ± 0.35
Pontine Tegmentum8.57 ± 0.34
Striatum7.88 ± 0.4
Subthalamus8.51 ± 0.41
Temporal Lobe8.53 ± 0.3
Thalamus8.33 ± 0.33
White Matter9.57 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fdft1CBCerebellum5.06
6.59
Fdft1CTXCerebral cortex20.22
14.1
Fdft1HIPHippocampal region10.09
9.26
Fdft1HPFHippocampal formation17.24
14.66
Fdft1HYHypothalamus8.12
6.4
Fdft1LSXLateral septal complex0.99
0.69
Fdft1MBMidbrain7.01
7.12
Fdft1MYMedulla15.23
16.7
Fdft1OLFOlfactory bulb14.56
10.71
Fdft1PPons12.48
13.79
Fdft1PALPallidum11.64
11.78
Fdft1RHPRetrohippocampal region33.84
25.69
Fdft1sAMYStriatum-like amygdalar nuclei12.14
8.1
Fdft1STRStriatum5.88
4.71
Fdft1STRdStriatum dorsal region5.27
4.62
Fdft1STRvStriatum ventral region6.14
4.37
Fdft1THThalamus9.24
7.24
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
FDFT_HUMAN_120 14 120 133 QVLEDFPTISLEFR PRIDE
PAp00001142 13 6 18 CLGHPEEFYNLVR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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