AutismKB 2.0

Annotation Detail for FER


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Basic Information Top
Gene Symbol:FER ( TYK3 )
Gene Full Name: fer (fps/fes related) tyrosine kinase
Band: 5q21.3
Quick LinksEntrez ID:2241; OMIM: 176942; Uniprot ID:FER_HUMAN; ENSEMBL ID: ENSG00000151422; HGNC ID: 3655
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile5 / 5555689
adult16 / 19391218
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor6 / 9635962
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal29 / 33603078
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain8 / 11009897
cervix1 / 4817120
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine1 / 2344724
kidney2 / 2117779
larynx0 / 241450 
liver7 / 20774333
lung7 / 33697420
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth2 / 6705229
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate2 / 18934510
salivary gland0 / 201550 
skin1 / 2105744
spleen2 / 5395237
stomach0 / 966190 
testis4 / 33044212
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206412_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.95
Adipocyte11.3
AdrenalCortex9.65
Adrenalgland7.55
Amygdala8.85
Appendix8.8
AtrioventricularNode7.3
BDCA4+_DentriticCells8.9
Bonemarrow8.75
BronchialEpithelialCells8.5
CD105+_Endothelial8.3
CD14+_Monocytes10.6
CD19+_BCells(neg._sel.)8.75
CD33+_Myeloid10.75
CD34+10.2
CD4+_Tcells8.9
CD56+_NKCells9.55
CD71+_EarlyErythroid8.1
CD8+_Tcells7.8
CardiacMyocytes11.5
Caudatenucleus7.65
Cerebellum7
CerebellumPeduncles10.05
CiliaryGanglion6.45
CingulateCortex9.55
Colorectaladenocarcinoma9.35
DorsalRootGanglion7.15
FetalThyroid9
Fetalbrain8.4
Fetalliver7.55
Fetallung6.7
GlobusPallidus6.5
Heart11.6
Hypothalamus9.05
Kidney7.35
Leukemia_chronicMyelogenousK-5627.85
Leukemia_promyelocytic-HL-607.7
Leukemialymphoblastic(MOLT-4)6.55
Liver11.85
Lung9.25
Lymphnode7
Lymphoma_burkitts(Daudi)11.25
Lymphoma_burkitts(Raji)12.5
MedullaOblongata7.7
OccipitalLobe7.7
OlfactoryBulb6.8
Ovary6.05
Pancreas7.1
PancreaticIslet9.35
ParietalLobe9.45
Pituitary10.45
Placenta8.5
Pons8.35
PrefrontalCortex10.25
Prostate9.75
Salivarygland7.05
SkeletalMuscle12.9
Skin7.8
SmoothMuscle9.8
Spinalcord8.9
SubthalamicNucleus8.05
SuperiorCervicalGanglion11.15
TemporalLobe8
Testis7.6
TestisGermCell10.8
TestisIntersitial10.85
TestisLeydigCell11.6
TestisSeminiferousTubule7.45
Thalamus8.75
Thymus6.65
Thyroid10.6
Tongue9.85
Tonsil8.6
Trachea7.2
TrigeminalGanglion9.6
Uterus6.9
UterusCorpus8.15
WholeBlood9.3
Wholebrain6.85
colon8.5
pineal_day10.4
pineal_night9.78
retina10.35
small_intestine7.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11918_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.75 ± 0.29
Basal Forebrain6.53 ± 0.23
Basal Part of Pons5.99 ± 0.33
Cerebellar Cortex6.32 ± 0.3
Cerebellar Nuclei6.11 ± 0.43
Claustrum6.48 ± 0.44
Epithalamus6.67 ± 0.17
Frontal Lobe6.44 ± 0.4
Globus Pallidus7.04 ± 0.2
Hypothalamus6.47 ± 0.37
Insula6.53 ± 0.36
Limbic Lobe6.61 ± 0.35
Mesencephalon6.52 ± 0.42
Myelencephalon6.52 ± 0.39
Occipital Lobe6.53 ± 0.34
Parietal Lobe6.5 ± 0.38
Pontine Tegmentum6.55 ± 0.34
Striatum6.72 ± 0.31
Subthalamus6.4 ± 0.25
Temporal Lobe6.45 ± 0.31
Thalamus6.54 ± 0.32
White Matter6.96 ± 0.31
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fert2CBCerebellum36.13
40.85
Fert2CTXCerebral cortex72.89
56.36
Fert2HIPHippocampal region51.32
82.03
Fert2HPFHippocampal formation51.78
63.85
Fert2HYHypothalamus21.88
15.96
Fert2LSXLateral septal complex40.95
30.27
Fert2MBMidbrain22.35
19.44
Fert2MYMedulla30.45
29.65
Fert2OLFOlfactory bulb55.65
45.02
Fert2PPons24.51
23.38
Fert2PALPallidum25.68
21.03
Fert2RHPRetrohippocampal region52.68
41.6
Fert2sAMYStriatum-like amygdalar nuclei32.02
21.82
Fert2STRStriatum29.31
20.31
Fert2STRdStriatum dorsal region26.07
18.09
Fert2STRvStriatum ventral region34.25
22.55
Fert2THThalamus26.01
22.67
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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