AutismKB 2.0

Annotation Detail for ALDOA


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Basic Information Top
Gene Symbol:ALDOA ( ALDA,GSD12,MGC10942,MGC17716,MGC17767 )
Gene Full Name: aldolase A, fructose-bisphosphate
Band: 16p11.2
Quick LinksEntrez ID:226; OMIM: 103850; Uniprot ID:ALDOA_HUMAN; ENSEMBL ID: ENSG00000149925; HGNC ID: 414
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body78 / 707611102
blastocyst54 / 62319866
fetus96 / 564012170
neonate9 / 31097289
infant15 / 23620635
juvenile66 / 555561187
adult2839 / 19391211464
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor15 / 127941172
bladder carcinoma18 / 174751030
breast (mammary gland) tumor149 / 941781582
cervical tumor96 / 343662793
chondrosarcoma55 / 82823664
colorectal tumor98 / 114246857
esophageal tumor5 / 17290289
gastrointestinal tumor163 / 1193691365
germ cell tumor180 / 263845682
glioma124 / 1068831160
head and neck tumor1196 / 1363028774
kidney tumor77 / 689591116
leukemia117 / 958421220
liver tumor133 / 963591380
lung tumor203 / 1031271968
lymphoma83 / 717551156
non-neoplasia76 / 97250781
normal1787 / 3360307531
ovarian tumor141 / 766821838
pancreatic tumor138 / 1046161319
primitive neuroectodermal tumor of the CNS165 / 1256801312
prostate cancer187 / 1026801821
retinoblastoma79 / 463561704
skin tumor300 / 1249492400
soft tissue/muscle tissue tumor92 / 125191734
uterine tumor42 / 90257465
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue16 / 131061220
adrenal gland18 / 33197542
ascites54 / 400151349
bladder29 / 29757974
blood76 / 123478615
bone39 / 71655544
bone marrow63 / 488011290
brain597 / 1100989542
cervix102 / 481712117
connective tissue31 / 149255207
ear0 / 162120 
embryonic tissue206 / 215722954
esophagus7 / 20209346
eye260 / 2110541231
heart126 / 896261405
intestine229 / 234472976
kidney129 / 211777609
larynx346 / 2414514330
liver149 / 207743717
lung299 / 336974887
lymph61 / 442701377
lymph node71 / 91610775
mammary gland176 / 1532711148
mouth17 / 67052253
muscle413 / 1077153834
nerve18 / 157681141
ovary157 / 1020511538
pancreas145 / 214812675
parathyroid9 / 20539438
pharynx768 / 4132818583
pituitary gland9 / 16585542
placenta239 / 280825851
prostate208 / 1893451098
salivary gland48 / 201552381
skin334 / 2105741586
spleen18 / 53952333
stomach72 / 96619745
testis55 / 330442166
thymus11 / 81131135
thyroid57 / 474731200
tonsil17 / 169991000
trachea0 / 524130 
umbilical cord6 / 13680438
uterus136 / 232878583
vascular18 / 51780347
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200966_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts5335.1
Adipocyte6172.35
AdrenalCortex813.45
Adrenalgland1265.95
Amygdala4612.45
Appendix516.05
AtrioventricularNode76.3
BDCA4+_DentriticCells2498.35
Bonemarrow1282.15
BronchialEpithelialCells5403.8
CD105+_Endothelial1883.45
CD14+_Monocytes4235.65
CD19+_BCells(neg._sel.)1660.45
CD33+_Myeloid5193.75
CD34+3505.9
CD4+_Tcells1892.4
CD56+_NKCells2806.65
CD71+_EarlyErythroid527.3
CD8+_Tcells1576.05
CardiacMyocytes3892.8
Caudatenucleus2766.5
Cerebellum2219.3
CerebellumPeduncles3287.15
CiliaryGanglion414
CingulateCortex2630.7
Colorectaladenocarcinoma3933.2
DorsalRootGanglion743
FetalThyroid2908.85
Fetalbrain965.1
Fetalliver162.55
Fetallung1517.85
GlobusPallidus1563.25
Heart16532.55
Hypothalamus5241.15
Kidney1142.55
Leukemia_chronicMyelogenousK-5623698.15
Leukemia_promyelocytic-HL-603154.15
Leukemialymphoblastic(MOLT-4)2560.45
Liver1119.35
Lung3169.7
Lymphnode1192.6
Lymphoma_burkitts(Daudi)2964.55
Lymphoma_burkitts(Raji)6784.55
MedullaOblongata3125.5
OccipitalLobe3058.05
OlfactoryBulb672.05
Ovary803.45
Pancreas1646.5
PancreaticIslet2399.6
ParietalLobe3106.4
Pituitary1941.4
Placenta1667.65
Pons2274.9
PrefrontalCortex5166.45
Prostate4657.7
Salivarygland876.25
SkeletalMuscle18082.4
Skin528.05
SmoothMuscle6133.45
Spinalcord2893.2
SubthalamicNucleus2783.55
SuperiorCervicalGanglion237
TemporalLobe4313
Testis1077.15
TestisGermCell564
TestisIntersitial406.3
TestisLeydigCell252.85
TestisSeminiferousTubule260.5
Thalamus6545
Thymus1895.2
Thyroid6538.1
Tongue4493.65
Tonsil1396.5
Trachea1015.9
TrigeminalGanglion269.1
Uterus1915.55
UterusCorpus1386.9
WholeBlood3610.35
Wholebrain7541.25
colon1815.7
pineal_day6000.02
pineal_night5689.92
retina5151.275
small_intestine1444.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P921584
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala13.85 ± 0.78
Basal Forebrain13.51 ± 0.23
Basal Part of Pons13.59 ± 0.46
Cerebellar Cortex12.89 ± 0.56
Cerebellar Nuclei13.72 ± 0.54
Claustrum13.99 ± 0.67
Epithalamus12.77 ± 0.83
Frontal Lobe13.43 ± 0.65
Globus Pallidus14.12 ± 0.3
Hypothalamus13.35 ± 0.63
Insula13.26 ± 0.62
Limbic Lobe13.5 ± 0.65
Mesencephalon13.59 ± 0.55
Myelencephalon13.47 ± 0.69
Occipital Lobe13.26 ± 0.73
Parietal Lobe13.38 ± 0.61
Pontine Tegmentum13.28 ± 0.65
Striatum13.66 ± 0.65
Subthalamus13.56 ± 0.13
Temporal Lobe13.26 ± 0.73
Thalamus13.49 ± 0.5
White Matter13.73 ± 0.52
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ALDOA_HUMAN_0 0 0 0 ADDGRPFPQVIK PRIDE
ALDOA_HUMAN_0 0 0 0 ALANSLACQGK PRIDE
ALDOA_HUMAN_0 0 0 0 FSHEEIAMATVTALR PRIDE
ALDOA_HUMAN_0 0 0 0 GGVVGIKVDK PRIDE
ALDOA_HUMAN_0 0 0 0 GILAADESTGSIAK PRIDE
ALDOA_HUMAN_0 0 0 0 GILAADESTGSIAKR PRIDE
ALDOA_HUMAN_0 0 0 0 IGEHTPSALAIMENANVLAR PRIDE
ALDOA_HUMAN_0 0 0 0 LQSIGTENTEENR PRIDE
ALDOA_HUMAN_0 0 0 0 QLLLTADDR PRIDE
ALDOA_HUMAN_0 0 0 0 RLQSIGTENTEENR PRIDE
ALDOA_HUMAN_0 0 0 0 YTPSGQAGAAASESLFVSNHAY PRIDE
ALDOA_HUMAN_1 12 1 12 PYQYPALTPEQK PRIDE
ALDOA_HUMAN_1 21 1 21 PYQYPALTPEQKKELSDIAHR PRIDE
ALDOA_HUMAN_101 10 101 110 GGVVGIKVDK PRIDE
ALDOA_HUMAN_102 7 102 108 GGVVGIK PRIDE
ALDOA_HUMAN_108 26 108 133 VDKGVVPLAGTNGETTTQGLDGLSER PRIDE
ALDOA_HUMAN_111 23 111 133 GVVPLAGTNGETTTQGLDGLSER PRIDE
ALDOA_HUMAN_112 23 112 134 GVVPLAGTNGETTTQGLDGLSER PRIDE
ALDOA_HUMAN_14 8 14 21 ELSDIAHR PRIDE
ALDOA_HUMAN_14 9 14 22 KELSDIAHR PRIDE
ALDOA_HUMAN_149 24 149 172 CVLKIGEHTPSALAIMENANVLAR PRIDE
ALDOA_HUMAN_153 20 153 172 IGEHTPSALAIMENANVLAR PRIDE
ALDOA_HUMAN_154 20 154 173 IGEHTPSALAIMENANVLAR PRIDE
ALDOA_HUMAN_173 28 173 200 YASICQQNGIVPIVEPEILPDGDHDLKR PRIDE
ALDOA_HUMAN_174 27 174 200 YASICQQNGIVPIVEPEILPDGDHDLK PRIDE
ALDOA_HUMAN_174 28 174 201 YASICQQNGIVPIVEPEILPDGDHDLKR PRIDE
ALDOA_HUMAN_2 12 2 13 PYQYPALTPEQK PRIDE
ALDOA_HUMAN_209 7 209 215 VLAAVYK PRIDE
ALDOA_HUMAN_215 28 215 242 ALSDHHIYLEGTLLKPNMVTPGHACTQK PRIDE
ALDOA_HUMAN_216 28 216 243 ALSDHHIYLEGTLLKPNMVTPGHACTQK PRIDE
ALDOA_HUMAN_22 20 22 41 IVAPGKGILAADESTGSIAK PRIDE
ALDOA_HUMAN_22 21 22 42 IVAPGKGILAADESTGSIAKR PRIDE
ALDOA_HUMAN_23 20 23 42 VAPGKGILAADESTGSIAKR PRIDE
ALDOA_HUMAN_243 15 243 257 FSHEEIAMATVTALR PRIDE
ALDOA_HUMAN_243 16 243 258 FSHEEIAMATVTALRR PRIDE
ALDOA_HUMAN_244 15 244 258 FSHEEIAMATVTALR PRIDE
ALDOA_HUMAN_244 16 244 259 FSHEEIAMATVTALRR PRIDE
ALDOA_HUMAN_259 30 259 288 TVPPAVTGITFLSGGQSEEEASINLNAINK PRIDE
ALDOA_HUMAN_260 30 260 289 TVPPAVTGITFLSGGQSEEEASINLNAINK PRIDE
ALDOA_HUMAN_28 14 28 41 GILAADESTGSIAK PRIDE
ALDOA_HUMAN_28 15 28 42 GILAADESTGSIAKR PRIDE
ALDOA_HUMAN_289 15 289 303 CPLLKPWALTFSYGR PRIDE
ALDOA_HUMAN_29 14 29 42 GILAADESTGSIAK PRIDE
ALDOA_HUMAN_290 15 290 304 CPLLKPWALTFSYGR PRIDE
ALDOA_HUMAN_305 8 305 312 ALQASALK PRIDE
ALDOA_HUMAN_323 8 323 330 AAQEEYVK PRIDE
ALDOA_HUMAN_323 9 323 331 AAQEEYVKR PRIDE
ALDOA_HUMAN_331 11 331 341 ALANSLACQGK PRIDE
ALDOA_HUMAN_331 12 331 342 RALANSLACQGK PRIDE
ALDOA_HUMAN_331 33 331 363 ALANSLACQGKYTPSGQAGAAASESLFVSNHAY PRIDE
ALDOA_HUMAN_332 11 332 342 ALANSLACQGK PRIDE
ALDOA_HUMAN_342 22 342 363 YTPSGQAGAAASESLFVSNHAY PRIDE
ALDOA_HUMAN_343 22 343 364 YTPSGQAGAAASESLFVSNHAY PRIDE
ALDOA_HUMAN_42 15 42 56 RLQSIGTENTEENRR PRIDE
ALDOA_HUMAN_43 13 43 55 LQSIGTENTEENR PRIDE
ALDOA_HUMAN_43 14 43 56 LQSIGTENTEENRR PRIDE
ALDOA_HUMAN_44 13 44 56 LQSIGTENTEENR PRIDE
ALDOA_HUMAN_44 14 44 57 LQSIGTENTEENRR PRIDE
ALDOA_HUMAN_60 27 60 86 QLLLTADDRVNPCIGGVILFHETLYQK PRIDE
ALDOA_HUMAN_60 9 60 68 QLLLTADDR PRIDE
ALDOA_HUMAN_61 8 61 68 LLLTADDR PRIDE
ALDOA_HUMAN_61 9 61 69 QLLLTADDR PRIDE
ALDOA_HUMAN_70 18 70 87 VNPCIGGVILFHETLYQK PRIDE
ALDOA_HUMAN_87 12 87 98 ADDGRPFPQVIK PRIDE
ALDOA_HUMAN_88 12 88 99 ADDGRPFPQVIK PRIDE
PAp00000230 27 338 364 ACQGKYTPSGQAGAAASESLFVSNHAY Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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