AutismKB 2.0

Annotation Detail for FGFR2


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Basic Information Top
Gene Symbol:FGFR2 ( BEK,BFR-1,CD332,CEK3,CFD1,ECT1,FLJ98662,JWS,K-SAM,KGFR,TK14,TK25 )
Gene Full Name: fibroblast growth factor receptor 2
Band: 10q26.13
Quick LinksEntrez ID:2263; OMIM: 176943; Uniprot ID:FGFR2_HUMAN; ENSEMBL ID: ENSG00000066468; HGNC ID: 3689
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst12 / 62319192
fetus68 / 564012120
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult129 / 193912166
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor19 / 119369159
germ cell tumor14 / 26384553
glioma13 / 106883121
head and neck tumor10 / 13630273
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal211 / 336030762
ovarian tumor3 / 7668239
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites18 / 40015449
bladder1 / 2975733
blood0 / 1234780 
bone3 / 7165541
bone marrow0 / 488010 
brain61 / 110098955
cervix0 / 481710 
connective tissue6 / 14925540
ear10 / 16212616
embryonic tissue28 / 215722129
esophagus0 / 202090 
eye11 / 21105452
heart3 / 8962633
intestine3 / 23447212
kidney8 / 21177737
larynx2 / 2414582
liver8 / 20774338
lung20 / 33697459
lymph0 / 442700 
lymph node0 / 916100 
mammary gland6 / 15327139
mouth6 / 6705289
muscle2 / 10771518
nerve1 / 1576863
ovary4 / 10205139
pancreas7 / 21481232
parathyroid6 / 20539292
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta12 / 28082542
prostate10 / 18934552
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach1 / 9661910
testis5 / 33044215
thymus2 / 8113124
thyroid3 / 4747363
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus13 / 23287855
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211401_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.9
Adipocyte10.8
AdrenalCortex15.5
Adrenalgland9.6
Amygdala20.05
Appendix13.1
AtrioventricularNode12.5
BDCA4+_DentriticCells10.05
Bonemarrow11.3
BronchialEpithelialCells10.15
CD105+_Endothelial10.15
CD14+_Monocytes11.25
CD19+_BCells(neg._sel.)11.5
CD33+_Myeloid11.3
CD34+11.25
CD4+_Tcells10.6
CD56+_NKCells11.4
CD71+_EarlyErythroid10.4
CD8+_Tcells8.9
CardiacMyocytes15.25
Caudatenucleus10.05
Cerebellum15.3
CerebellumPeduncles15
CiliaryGanglion9.65
CingulateCortex21.3
Colorectaladenocarcinoma11.05
DorsalRootGanglion10.7
FetalThyroid10.75
Fetalbrain10.65
Fetalliver9.85
Fetallung9.6
GlobusPallidus9.35
Heart16
Hypothalamus12.7
Kidney9.7
Leukemia_chronicMyelogenousK-5629.95
Leukemia_promyelocytic-HL-609.75
Leukemialymphoblastic(MOLT-4)8.6
Liver19.25
Lung11.4
Lymphnode9.3
Lymphoma_burkitts(Daudi)15.15
Lymphoma_burkitts(Raji)15.85
MedullaOblongata13.85
OccipitalLobe19.95
OlfactoryBulb8.7
Ovary7.55
Pancreas8.9
PancreaticIslet11.8
ParietalLobe13.95
Pituitary13.1
Placenta11.4
Pons12.2
PrefrontalCortex18.7
Prostate12.4
Salivarygland10.25
SkeletalMuscle13.4
Skin12.05
SmoothMuscle12.35
Spinalcord20.3
SubthalamicNucleus10.65
SuperiorCervicalGanglion13.45
TemporalLobe10.1
Testis9.6
TestisGermCell8
TestisIntersitial9.5
TestisLeydigCell11.55
TestisSeminiferousTubule8.6
Thalamus11.6
Thymus8.05
Thyroid14.25
Tongue12.3
Tonsil10.85
Trachea12.15
TrigeminalGanglion12.85
Uterus8.8
UterusCorpus10.2
WholeBlood11.05
Wholebrain9.95
colon13.5
pineal_day12.3
pineal_night12.7
retina49.625
small_intestine10.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P303149
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.17 ± 0.78
Basal Forebrain8.22 ± 0.55
Basal Part of Pons8.04 ± 0.59
Cerebellar Cortex7.55 ± 0.37
Cerebellar Nuclei9.34 ± 0.8
Claustrum7.51 ± 0.36
Epithalamus7.63 ± 0.84
Frontal Lobe7.77 ± 0.89
Globus Pallidus9.95 ± 0.45
Hypothalamus7.05 ± 0.48
Insula7.03 ± 0.35
Limbic Lobe7.19 ± 0.74
Mesencephalon7.9 ± 1.02
Myelencephalon7.89 ± 0.77
Occipital Lobe7.99 ± 0.71
Parietal Lobe7.78 ± 0.84
Pontine Tegmentum8.03 ± 0.6
Striatum8.14 ± 0.94
Subthalamus8.57 ± 0.55
Temporal Lobe7.35 ± 0.61
Thalamus8.26 ± 0.62
White Matter10.72 ± 0.53
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fgfr2CBCerebellum17.2
14.98
Fgfr2CTXCerebral cortex5.34
3.02
Fgfr2HIPHippocampal region10.36
7.05
Fgfr2HPFHippocampal formation14.29
8.96
Fgfr2HYHypothalamus6.14
3.82
Fgfr2LSXLateral septal complex7.03
4.59
Fgfr2MBMidbrain10.17
6.36
Fgfr2MYMedulla24.78
16.92
Fgfr2OLFOlfactory bulb17.08
10.41
Fgfr2PPons22.33
14.41
Fgfr2PALPallidum8.11
4.86
Fgfr2RHPRetrohippocampal region22.28
12.3
Fgfr2sAMYStriatum-like amygdalar nuclei5.89
3.83
Fgfr2STRStriatum6.11
3.55
Fgfr2STRdStriatum dorsal region6.22
3.59
Fgfr2STRvStriatum ventral region6.06
2.99
Fgfr2THThalamus7.83
5.46
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00137330 11 120 130 DSGLYACTASR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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