AutismKB 2.0

Annotation Detail for FGG


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Basic Information Top
Gene Symbol:FGG ( - )
Gene Full Name: fibrinogen gamma chain
Band: 4q32.1
Quick LinksEntrez ID:2266; OMIM: 134850; Uniprot ID:FIBG_HUMAN; ENSEMBL ID: ENSG00000171557; HGNC ID: 3694
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus223 / 564012395
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult661 / 1939121340
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma4 / 8282348
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor10 / 26384537
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia39 / 95842406
liver tumor172 / 963591784
lung tumor32 / 103127310
lymphoma0 / 717550 
non-neoplasia8 / 9725082
normal1660 / 3360307494
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites0 / 400150 
bladder0 / 297570 
blood39 / 123478315
bone1 / 7165513
bone marrow0 / 488010 
brain8 / 11009897
cervix2 / 4817141
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye0 / 2110540 
heart16 / 89626178
intestine1 / 2344724
kidney1 / 2117774
larynx0 / 241450 
liver1663 / 2077438005
lung65 / 336974192
lymph0 / 442700 
lymph node0 / 916100 
mammary gland11 / 15327171
mouth0 / 670520 
muscle45 / 107715417
nerve0 / 157680 
ovary1 / 1020519
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta13 / 28082546
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen3 / 5395255
stomach0 / 966190 
testis2 / 3304426
thymus0 / 811310 
thyroid8 / 47473168
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219612_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.95
Adipocyte5.9
AdrenalCortex7.25
Adrenalgland12
Amygdala5.95
Appendix7.1
AtrioventricularNode6.8
BDCA4+_DentriticCells5.9
Bonemarrow6.8
BronchialEpithelialCells5.65
CD105+_Endothelial6.05
CD14+_Monocytes6.45
CD19+_BCells(neg._sel.)6.55
CD33+_Myeloid7.5
CD34+7.25
CD4+_Tcells6.1
CD56+_NKCells6.8
CD71+_EarlyErythroid5.85
CD8+_Tcells5.4
CardiacMyocytes9.9
Caudatenucleus5.45
Cerebellum4.95
CerebellumPeduncles7.35
CiliaryGanglion5.3
CingulateCortex6.45
Colorectaladenocarcinoma6
DorsalRootGanglion5.45
FetalThyroid7.65
Fetalbrain5.8
Fetalliver10016.85
Fetallung740.45
GlobusPallidus5.05
Heart10.95
Hypothalamus6.4
Kidney5.25
Leukemia_chronicMyelogenousK-5625.45
Leukemia_promyelocytic-HL-605.3
Leukemialymphoblastic(MOLT-4)4.75
Liver6412.05
Lung6.85
Lymphnode5.1
Lymphoma_burkitts(Daudi)7.95
Lymphoma_burkitts(Raji)9.1
MedullaOblongata5.55
OccipitalLobe5.4
OlfactoryBulb4.65
Ovary36.45
Pancreas5.8
PancreaticIslet154.05
ParietalLobe6.65
Pituitary7.05
Placenta11.05
Pons6.2
PrefrontalCortex7.15
Prostate7
Salivarygland4.95
SkeletalMuscle8.7
Skin5.3
SmoothMuscle6.85
Spinalcord6.45
SubthalamicNucleus5.65
SuperiorCervicalGanglion9.95
TemporalLobe5.6
Testis5.1
TestisGermCell4.9
TestisIntersitial5.7
TestisLeydigCell6.2
TestisSeminiferousTubule5.15
Thalamus6.25
Thymus4.5
Thyroid7.45
Tongue7.15
Tonsil5.9
Trachea5.05
TrigeminalGanglion9.15
Uterus4.8
UterusCorpus6.65
WholeBlood6.45
Wholebrain4.7
colon6.1
pineal_day7.18
pineal_night7.16
retina7.225
small_intestine5.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P148088
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.27 ± 1.14
Basal Forebrain2.09 ± 0.67
Basal Part of Pons1.38 ± 0.4
Cerebellar Cortex1.52 ± 0.7
Cerebellar Nuclei2.13 ± 0.71
Claustrum2.69 ± 0.9
Epithalamus1.56 ± 0.76
Frontal Lobe1.61 ± 0.78
Globus Pallidus2.29 ± 0.55
Hypothalamus1.77 ± 0.69
Insula1.73 ± 0.58
Limbic Lobe1.76 ± 0.78
Mesencephalon2.05 ± 0.85
Myelencephalon1.75 ± 0.78
Occipital Lobe2.03 ± 0.75
Parietal Lobe1.72 ± 0.78
Pontine Tegmentum1.84 ± 0.84
Striatum1.99 ± 0.81
Subthalamus1.92 ± 0.78
Temporal Lobe1.71 ± 0.9
Thalamus1.69 ± 0.66
White Matter2.52 ± 0.6
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
FggCBCerebellum0.14
0.42
FggCTXCerebral cortex0.87
1.17
FggHIPHippocampal region0.13
0.21
FggHPFHippocampal formation0.11
0.24
FggHYHypothalamus0.48
0.59
FggLSXLateral septal complex0.04
0
FggMBMidbrain0.38
0.72
FggMYMedulla0.17
0.36
FggOLFOlfactory bulb1.45
2.06
FggPPons0.25
0.59
FggPALPallidum0.02
0.03
FggRHPRetrohippocampal region0.09
0.32
FggsAMYStriatum-like amygdalar nuclei0.31
0.53
FggSTRStriatum0.09
0.13
FggSTRdStriatum dorsal region0.07
0.08
FggSTRvStriatum ventral region0.06
0.07
FggTHThalamus0.2
0.46
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
FIBG_HUMAN_113 21 113 133 KMLEEIMKYEASILTHDSSIR PRIDE
FIBG_HUMAN_113 8 113 120 KMLEEIMK PRIDE
FIBG_HUMAN_114 20 114 133 MLEEIMKYEASILTHDSSIR PRIDE
FIBG_HUMAN_121 13 121 133 YEASILTHDSSIR PRIDE
FIBG_HUMAN_134 12 134 145 YLQEIYNSNNQK PRIDE
FIBG_HUMAN_151 26 151 176 EKVAQLEAQCQEPCKDTVQIHDITGK PRIDE
FIBG_HUMAN_153 13 153 165 VAQLEAQCQEPCK PRIDE
FIBG_HUMAN_153 24 153 176 VAQLEAQCQEPCKDTVQIHDITGK PRIDE
FIBG_HUMAN_153 32 153 184 VAQLEAQCQEPCKDTVQIHDITGKDCQDIANK PRIDE
FIBG_HUMAN_166 11 166 176 DTVQIHDITGK PRIDE
FIBG_HUMAN_188 11 188 198 QSGLYFIKPLK PRIDE
FIBG_HUMAN_222 10 222 231 RLDGSVDFKK PRIDE
FIBG_HUMAN_223 8 223 230 LDGSVDFK PRIDE
FIBG_HUMAN_231 7 231 237 KNWIQYK PRIDE
FIBG_HUMAN_238 20 238 257 EGFGHLSPTGTTEFWLGNEK PRIDE
FIBG_HUMAN_258 15 258 272 IHLISTQSAIPYALR PRIDE
FIBG_HUMAN_258 24 258 281 IHLISTQSAIPYALRVELEDWNGR PRIDE
FIBG_HUMAN_273 9 273 281 VELEDWNGR PRIDE
FIBG_HUMAN_282 10 282 291 TSTADYAMFK PRIDE
FIBG_HUMAN_282 19 282 300 TSTADYAMFKVGPEADKYR PRIDE
FIBG_HUMAN_31 9 31 39 DNCCILDER PRIDE
FIBG_HUMAN_364 18 364 381 CHAGHLNGVYYQGGTYSK PRIDE
FIBG_HUMAN_399 7 399 405 TRWYSMK PRIDE
FIBG_HUMAN_40 21 40 60 FGSYCPTTCGIADFLSTYQTK PRIDE
FIBG_HUMAN_417 15 417 431 LTIGEGQQHHLGGAK PRIDE
FIBG_HUMAN_88 23 88 110 AIQLTYNPDESSKPNMIDAATLK PRIDE
PAp00000009 18 365 382 CHAGHLNGVYYQGGTYSK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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