AutismKB 2.0

Annotation Detail for NID2


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Basic Information Top
Gene Symbol:NID2 ( NID-2 )
Gene Full Name: nidogen 2 (osteonidogen)
Band: 14q22.1
Quick LinksEntrez ID:22795; OMIM: 605399; Uniprot ID:NID2_HUMAN; ENSEMBL ID: ENSG00000087303; HGNC ID: 13389
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body16 / 70761226
blastocyst1 / 6231916
fetus49 / 56401286
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult88 / 193912145
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma11 / 82823132
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor9 / 26384534
glioma0 / 1068830 
head and neck tumor3 / 13630222
kidney tumor3 / 6895943
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal164 / 336030748
ovarian tumor3 / 7668239
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone2 / 7165527
bone marrow0 / 488010 
brain27 / 110098924
cervix0 / 481710 
connective tissue5 / 14925533
ear16 / 16212986
embryonic tissue18 / 21572283
esophagus0 / 202090 
eye8 / 21105437
heart11 / 89626122
intestine4 / 23447217
kidney15 / 21177770
larynx1 / 2414541
liver2 / 2077439
lung10 / 33697429
lymph0 / 442700 
lymph node2 / 9161021
mammary gland1 / 1532716
mouth0 / 670520 
muscle16 / 107715148
nerve2 / 15768126
ovary4 / 10205139
pancreas3 / 21481213
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta25 / 28082589
prostate0 / 1893450 
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach2 / 9661920
testis9 / 33044227
thymus1 / 8113112
thyroid3 / 4747363
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204114_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.65
Adipocyte66.05
AdrenalCortex7.15
Adrenalgland6.3
Amygdala6.4
Appendix12.1
AtrioventricularNode8.95
BDCA4+_DentriticCells6.7
Bonemarrow6.25
BronchialEpithelialCells5.9
CD105+_Endothelial7.3
CD14+_Monocytes6.65
CD19+_BCells(neg._sel.)6.6
CD33+_Myeloid7.8
CD34+10.6
CD4+_Tcells6.05
CD56+_NKCells6.95
CD71+_EarlyErythroid5.9
CD8+_Tcells5.3
CardiacMyocytes283.25
Caudatenucleus5.55
Cerebellum5
CerebellumPeduncles7.2
CiliaryGanglion11.65
CingulateCortex6.4
Colorectaladenocarcinoma6.1
DorsalRootGanglion7.45
FetalThyroid148
Fetalbrain6.1
Fetalliver20.95
Fetallung76.65
GlobusPallidus4.55
Heart34.25
Hypothalamus6.7
Kidney7.35
Leukemia_chronicMyelogenousK-5625.5
Leukemia_promyelocytic-HL-605.4
Leukemialymphoblastic(MOLT-4)4.9
Liver11.25
Lung7.1
Lymphnode6.8
Lymphoma_burkitts(Daudi)8.1
Lymphoma_burkitts(Raji)8.8
MedullaOblongata5.6
OccipitalLobe5.55
OlfactoryBulb24.45
Ovary7.75
Pancreas6.2
PancreaticIslet7.7
ParietalLobe6.7
Pituitary7.5
Placenta119.15
Pons6
PrefrontalCortex7.6
Prostate7.45
Salivarygland5.1
SkeletalMuscle7.5
Skin6.85
SmoothMuscle188.2
Spinalcord6.9
SubthalamicNucleus5.9
SuperiorCervicalGanglion9.35
TemporalLobe5.7
Testis5.4
TestisGermCell5.35
TestisIntersitial5.25
TestisLeydigCell7.15
TestisSeminiferousTubule5.5
Thalamus6.4
Thymus5.05
Thyroid167.8
Tongue6.2
Tonsil6.15
Trachea6.05
TrigeminalGanglion6.55
Uterus12.25
UterusCorpus11.2
WholeBlood6.7
Wholebrain4.95
colon20.4
pineal_day7.96
pineal_night11.66
retina26.975
small_intestine20.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10873_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.66 ± 0.72
Basal Forebrain4.73 ± 0.43
Basal Part of Pons4.25 ± 0.62
Cerebellar Cortex3.94 ± 0.64
Cerebellar Nuclei4.93 ± 0.75
Claustrum4.83 ± 0.58
Epithalamus5.21 ± 0.45
Frontal Lobe4.22 ± 0.73
Globus Pallidus5.53 ± 0.24
Hypothalamus4.14 ± 0.61
Insula4.1 ± 0.74
Limbic Lobe4.31 ± 0.68
Mesencephalon4.47 ± 0.6
Myelencephalon4.56 ± 0.69
Occipital Lobe4.28 ± 0.57
Parietal Lobe4.48 ± 0.74
Pontine Tegmentum4.48 ± 0.74
Striatum4.73 ± 0.52
Subthalamus4.87 ± 0.97
Temporal Lobe4.45 ± 0.63
Thalamus4.39 ± 0.58
White Matter6.27 ± 0.43
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nid2CBCerebellum0.85
1.55
Nid2CTXCerebral cortex0.5
0.77
Nid2HIPHippocampal region0.81
1.78
Nid2HPFHippocampal formation0.64
1.22
Nid2HYHypothalamus0.29
0.22
Nid2LSXLateral septal complex0.08
0.06
Nid2MBMidbrain0.4
0.83
Nid2MYMedulla1.42
3.05
Nid2OLFOlfactory bulb1.94
1.81
Nid2PPons0.34
0.59
Nid2PALPallidum0.04
0.03
Nid2RHPRetrohippocampal region0.35
0.46
Nid2sAMYStriatum-like amygdalar nuclei0.21
0.19
Nid2STRStriatum0.15
0.18
Nid2STRdStriatum dorsal region0.19
0.25
Nid2STRvStriatum ventral region0.06
0.04
Nid2THThalamus0.59
1.36
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00092703 10 1241 1250 GNLYWTDWNR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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