AutismKB 2.0

Annotation Detail for TFEC


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Basic Information Top
Gene Symbol:TFEC ( TCFEC,TFECL,bHLHe34 )
Gene Full Name: transcription factor EC
Band: 7q31.2
Quick LinksEntrez ID:22797; OMIM: 604732; Uniprot ID:TFEC_HUMAN; ENSEMBL ID: ENSG00000105967; HGNC ID: 11754
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult26 / 193912113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia6 / 9584262
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma2 / 7175527
non-neoplasia3 / 9725030
normal37 / 336030711
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood8 / 12347864
bone0 / 716550 
bone marrow3 / 4880161
brain6 / 11009895
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney17 / 21177780
larynx0 / 241450 
liver0 / 2077430 
lung4 / 33697411
lymph2 / 4427045
lymph node1 / 9161010
mammary gland1 / 1532716
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary1 / 1020519
pancreas1 / 2148124
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach2 / 9661920
testis1 / 3304423
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206715_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.75
Adipocyte5.7
AdrenalCortex6.4
Adrenalgland4.95
Amygdala6
Appendix6.5
AtrioventricularNode6.1
BDCA4+_DentriticCells58.55
Bonemarrow6.15
BronchialEpithelialCells5.5
CD105+_Endothelial5.85
CD14+_Monocytes164.1
CD19+_BCells(neg._sel.)6.5
CD33+_Myeloid493.3
CD34+152.15
CD4+_Tcells5.95
CD56+_NKCells6.6
CD71+_EarlyErythroid5.55
CD8+_Tcells5.45
CardiacMyocytes8.55
Caudatenucleus5.15
Cerebellum4.7
CerebellumPeduncles6.65
CiliaryGanglion5.85
CingulateCortex6
Colorectaladenocarcinoma5.75
DorsalRootGanglion5.35
FetalThyroid5.7
Fetalbrain5.7
Fetalliver5.15
Fetallung4.45
GlobusPallidus4.45
Heart8.1
Hypothalamus6.1
Kidney4.9
Leukemia_chronicMyelogenousK-5625.15
Leukemia_promyelocytic-HL-605.15
Leukemialymphoblastic(MOLT-4)4.45
Liver8.1
Lung6.3
Lymphnode5.1
Lymphoma_burkitts(Daudi)7.6
Lymphoma_burkitts(Raji)8.65
MedullaOblongata5.25
OccipitalLobe5.1
OlfactoryBulb4.55
Ovary4
Pancreas4.75
PancreaticIslet6.1
ParietalLobe6.3
Pituitary6.7
Placenta5.7
Pons5.95
PrefrontalCortex6.9
Prostate6.75
Salivarygland4.8
SkeletalMuscle7.35
Skin8
SmoothMuscle6.4
Spinalcord6.15
SubthalamicNucleus5.4
SuperiorCervicalGanglion23.7
TemporalLobe5.35
Testis4.95
TestisGermCell4.6
TestisIntersitial4.85
TestisLeydigCell5.8
TestisSeminiferousTubule5
Thalamus5.9
Thymus4.4
Thyroid7.15
Tongue6.1
Tonsil5.65
Trachea4.75
TrigeminalGanglion15.5
Uterus4.65
UterusCorpus5.45
WholeBlood8.85
Wholebrain4.6
colon5.85
pineal_day7.04
pineal_night6.98
retina7
small_intestine6.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P98210
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.77 ± 0.6
Basal Forebrain5.54 ± 0.31
Basal Part of Pons5.87 ± 0.22
Cerebellar Cortex4.73 ± 0.42
Cerebellar Nuclei6.47 ± 0.33
Claustrum5.55 ± 0.8
Epithalamus6.52 ± 0.46
Frontal Lobe5.16 ± 0.7
Globus Pallidus7.11 ± 0.34
Hypothalamus5.44 ± 0.93
Insula5.63 ± 0.7
Limbic Lobe5.22 ± 0.73
Mesencephalon5.32 ± 0.88
Myelencephalon5.4 ± 0.7
Occipital Lobe4.81 ± 0.82
Parietal Lobe5.32 ± 0.66
Pontine Tegmentum5.34 ± 0.68
Striatum5.88 ± 0.5
Subthalamus5.94 ± 0.18
Temporal Lobe5.5 ± 0.56
Thalamus5.38 ± 0.5
White Matter7.35 ± 0.67
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
TcfecCBCerebellum5.07
5.42
TcfecCTXCerebral cortex8.88
6.22
TcfecHIPHippocampal region3
2.59
TcfecHPFHippocampal formation2.78
2.24
TcfecHYHypothalamus0.59
0.56
TcfecLSXLateral septal complex0.13
0.21
TcfecMBMidbrain0.84
0.94
TcfecMYMedulla5.92
5.23
TcfecOLFOlfactory bulb10.88
8.73
TcfecPPons2.5
2.43
TcfecPALPallidum0.71
0.58
TcfecRHPRetrohippocampal region2.39
1.7
TcfecsAMYStriatum-like amygdalar nuclei3.36
2.1
TcfecSTRStriatum3
2.01
TcfecSTRdStriatum dorsal region3.37
2.22
TcfecSTRvStriatum ventral region2.25
1.65
TcfecTHThalamus1.05
0.78
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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