AutismKB 2.0

Annotation Detail for ITGA11


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Basic Information Top
Gene Symbol:ITGA11 ( HsT18964 )
Gene Full Name: integrin, alpha 11
Band: 15q23
Quick LinksEntrez ID:22801; OMIM: 604789; Uniprot ID:ITA11_HUMAN; ENSEMBL ID: ENSG00000137809; HGNC ID: 6136
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body10 / 70761141
blastocyst2 / 6231932
fetus2 / 5640123
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult45 / 193912123
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma2 / 10688318
head and neck tumor7 / 13630251
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal66 / 336030719
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone22 / 71655307
bone marrow3 / 4880161
brain13 / 110098911
cervix1 / 4817120
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine6 / 23447225
kidney5 / 21177723
larynx0 / 241450 
liver4 / 20774319
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland5 / 15327132
mouth1 / 6705214
muscle2 / 10771518
nerve0 / 157680 
ovary1 / 1020519
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland4 / 20155198
skin4 / 21057418
spleen1 / 5395218
stomach0 / 966190 
testis3 / 3304429
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord1 / 1368073
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15620_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.68 ± 1.19
Basal Forebrain2.1 ± 0.22
Basal Part of Pons1.89 ± 0.53
Cerebellar Cortex2 ± 0.83
Cerebellar Nuclei2.44 ± 0.71
Claustrum3.54 ± 0.69
Epithalamus2.23 ± 0.85
Frontal Lobe2.23 ± 0.87
Globus Pallidus2.28 ± 0.63
Hypothalamus2.34 ± 0.81
Insula2.47 ± 0.68
Limbic Lobe2.09 ± 0.84
Mesencephalon2.51 ± 0.91
Myelencephalon2.3 ± 0.83
Occipital Lobe3.04 ± 1.12
Parietal Lobe2.39 ± 0.89
Pontine Tegmentum2.27 ± 0.77
Striatum1.95 ± 0.82
Subthalamus2.34 ± 0.87
Temporal Lobe2.09 ± 0.81
Thalamus2.15 ± 0.73
White Matter2 ± 0.4
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Itga11CBCerebellum0.36
0.7
Itga11CTXCerebral cortex0.37
0.4
Itga11HIPHippocampal region0.34
0.43
Itga11HPFHippocampal formation0.44
0.48
Itga11HYHypothalamus0.22
0.26
Itga11LSXLateral septal complex0.3
0.27
Itga11MBMidbrain0.45
0.46
Itga11MYMedulla0.54
0.41
Itga11OLFOlfactory bulb0.7
1.31
Itga11PPons0.3
0.2
Itga11PALPallidum0.15
0.2
Itga11RHPRetrohippocampal region0.52
0.47
Itga11sAMYStriatum-like amygdalar nuclei0.32
0.18
Itga11STRStriatum0.25
0.2
Itga11STRdStriatum dorsal region0.17
0.17
Itga11STRvStriatum ventral region0.41
0.26
Itga11THThalamus0.27
0.34
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ITA11_HUMAN_718 13 718 730 AVLLSSGQELCER PRIDE
ITA11_HUMAN_837 10 837 846 VAVEATLENR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018