Annotation Detail for XRN2
Basic Information Top
| Gene Symbol: | XRN2 ( - ) |
|---|---|
| Gene Full Name: | 5'-3' exoribonuclease 2 |
| Band: | 20p11.22 |
| Quick Links | Entrez ID:22803; OMIM: 608851; Uniprot ID:XRN2_HUMAN; ENSEMBL ID: ENSG00000088930; HGNC ID: 12836 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.255932
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 15 / 70761 | 211 |  |
| blastocyst | 16 / 62319 | 256 | |
| fetus | 70 / 564012 | 124 |  |
| neonate | 7 / 31097 | 225 | |
| infant | 3 / 23620 | 127 | |
| juvenile | 14 / 55556 | 251 | |
| adult | 171 / 1939121 | 88 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 16 / 94178 | 169 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 10 / 82823 | 120 | |
| colorectal tumor | 13 / 114246 | 113 | |
| esophageal tumor | 3 / 17290 | 173 | |
| gastrointestinal tumor | 17 / 119369 | 142 | |
| germ cell tumor | 49 / 263845 | 185 | |
| glioma | 6 / 106883 | 56 | |
| head and neck tumor | 28 / 136302 | 205 | |
| kidney tumor | 8 / 68959 | 116 | |
| leukemia | 9 / 95842 | 93 | |
| liver tumor | 20 / 96359 | 207 | |
| lung tumor | 15 / 103127 | 145 | |
| lymphoma | 5 / 71755 | 69 | |
| non-neoplasia | 13 / 97250 | 133 | |
| normal | 304 / 3360307 | 90 | |
| ovarian tumor | 15 / 76682 | 195 | |
| pancreatic tumor | 3 / 104616 | 28 |  |
| primitive neuroectodermal tumor of the CNS | 17 / 125680 | 135 | |
| prostate cancer | 6 / 102680 | 58 | |
| retinoblastoma | 5 / 46356 | 107 | |
| skin tumor | 17 / 124949 | 136 | |
| soft tissue/muscle tissue tumor | 16 / 125191 | 127 | |
| uterine tumor | 18 / 90257 | 199 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 3 / 33197 | 90 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 3 / 29757 | 100 | |
| blood | 13 / 123478 | 105 | |
| bone | 10 / 71655 | 139 | |
| bone marrow | 5 / 48801 | 102 | |
| brain | 95 / 1100989 | 86 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 17 / 149255 | 113 | |
| ear | 3 / 16212 | 185 | |
| embryonic tissue | 43 / 215722 | 199 | |
| esophagus | 3 / 20209 | 148 | |
| eye | 20 / 211054 | 94 | |
| heart | 6 / 89626 | 66 | |
| intestine | 24 / 234472 | 102 | |
| kidney | 26 / 211777 | 122 | |
| larynx | 6 / 24145 | 248 | |
| liver | 25 / 207743 | 120 | |
| lung | 51 / 336974 | 151 | |
| lymph | 3 / 44270 | 67 | |
| lymph node | 5 / 91610 | 54 | |
| mammary gland | 20 / 153271 | 130 | |
| mouth | 16 / 67052 | 238 | |
| muscle | 8 / 107715 | 74 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 18 / 102051 | 176 | |
| pancreas | 8 / 214812 | 37 | |
| parathyroid | 1 / 20539 | 48 | |
| pharynx | 6 / 41328 | 145 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 28 / 280825 | 99 | |
| prostate | 8 / 189345 | 42 | |
| salivary gland | 2 / 20155 | 99 | |
| skin | 25 / 210574 | 118 | |
| spleen | 2 / 53952 | 37 | |
| stomach | 13 / 96619 | 134 | |
| testis | 74 / 330442 | 223 | |
| thymus | 15 / 81131 | 184 | |
| thyroid | 5 / 47473 | 105 | |
| tonsil | 1 / 16999 | 58 | |
| trachea | 17 / 52413 | 324 | |
| umbilical cord | 4 / 13680 | 292 | |
| uterus | 32 / 232878 | 137 | |
| vascular | 9 / 51780 | 173 | |
Microarray in - Probe name: CUST_9915_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.73 ± 0.37 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 5.68 ± 0.3 | |
| Basal Part of Pons | 5.3 ± 0.37 | |
| Cerebellar Cortex | 5.94 ± 0.29 | |
| Cerebellar Nuclei | 5.6 ± 0.26 | |
| Claustrum | 5.58 ± 0.47 | |
| Epithalamus | 5.73 ± 0.58 | |
| Frontal Lobe | 5.46 ± 0.42 | |
| Globus Pallidus | 5.92 ± 0.5 | |
| Hypothalamus | 5.52 ± 0.35 | |
| Insula | 5.29 ± 0.33 | |
| Limbic Lobe | 5.68 ± 0.46 | |
| Mesencephalon | 5.6 ± 0.46 | |
| Myelencephalon | 5.66 ± 0.48 | |
| Occipital Lobe | 5.84 ± 0.38 | |
| Parietal Lobe | 5.54 ± 0.41 | |
| Pontine Tegmentum | 5.57 ± 0.43 | |
| Striatum | 5.67 ± 0.45 | |
| Subthalamus | 5.23 ± 0.13 | |
| Temporal Lobe | 5.52 ± 0.46 | |
| Thalamus | 5.54 ± 0.33 | |
| White Matter | 6.39 ± 0.12 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Xrn2 | CB | Cerebellum | 55.4 | |
| 63.59 | | |||
| Xrn2 | CTX | Cerebral cortex | 100 | |
| 92.51 | | |||
| Xrn2 | HIP | Hippocampal region | 82.71 | |
| 100 | | |||
| Xrn2 | HPF | Hippocampal formation | 86.87 | |
| 100 | | |||
| Xrn2 | HY | Hypothalamus | 61.88 | |
| 50.25 | | |||
| Xrn2 | LSX | Lateral septal complex | 75.61 | |
| 56.38 | | |||
| Xrn2 | MB | Midbrain | 62.85 | |
| 53.71 | | |||
| Xrn2 | MY | Medulla | 59.23 | |
| 57.2 | | |||
| Xrn2 | OLF | Olfactory bulb | 84.73 | |
| 79.02 | | |||
| Xrn2 | P | Pons | 51.59 | |
| 48.91 | | |||
| Xrn2 | PAL | Pallidum | 62.47 | |
| 55.42 | | |||
| Xrn2 | RHP | Retrohippocampal region | 95.8 | |
| 84.75 | | |||
| Xrn2 | sAMY | Striatum-like amygdalar nuclei | 83.35 | |
| 62.67 | | |||
| Xrn2 | STR | Striatum | 96.39 | |
| 75.75 | | |||
| Xrn2 | STRd | Striatum dorsal region | 100 | |
| 79.93 | | |||
| Xrn2 | STRv | Striatum ventral region | 100 | |
| 78.37 | | |||
| Xrn2 | TH | Thalamus | 74.65 | |
| 62.32 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00025434 | 21 | 285 | 305 | GKHDELADSLPCAEGEFIFLR | Peptide Atlas |
| XRN2_HUMAN_124 | 9 | 124 | 132 | EGMEAAVEK | PRIDE |
| XRN2_HUMAN_2 | 7 | 2 | 8 | GVPAFFR | PRIDE |
| XRN2_HUMAN_316 | 15 | 316 | 330 | ELTMASLPFTFDVER | PRIDE |