AutismKB 2.0

Annotation Detail for MTF2


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Basic Information Top
Gene Symbol:MTF2 ( M96,PCL2,RP5-976O13.1,dJ976O13.2 )
Gene Full Name: metal response element binding transcription factor 2
Band: 1p22.1
Quick LinksEntrez ID:22823; OMIM: 609882; Uniprot ID:MTF2_HUMAN; ENSEMBL ID: ENSG00000143033; HGNC ID: 29535
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst4 / 6231964
fetus18 / 56401231
neonate4 / 31097128
infant2 / 2362084
juvenile8 / 55556143
adult75 / 193912138
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma1 / 1747557
breast (mammary gland) tumor4 / 9417842
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor2 / 11424617
esophageal tumor1 / 1729057
gastrointestinal tumor2 / 11936916
germ cell tumor23 / 26384587
glioma2 / 10688318
head and neck tumor7 / 13630251
kidney tumor6 / 6895987
leukemia12 / 95842125
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma6 / 7175583
non-neoplasia4 / 9725041
normal141 / 336030741
ovarian tumor4 / 7668252
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS11 / 12568087
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor3 / 12494924
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites0 / 400150 
bladder2 / 2975767
blood7 / 12347856
bone3 / 7165541
bone marrow3 / 4880161
brain29 / 110098926
cervix6 / 48171124
connective tissue4 / 14925526
ear1 / 1621261
embryonic tissue18 / 21572283
esophagus1 / 2020949
eye6 / 21105428
heart2 / 8962622
intestine5 / 23447221
kidney17 / 21177780
larynx0 / 241450 
liver9 / 20774343
lung16 / 33697447
lymph2 / 4427045
lymph node17 / 91610185
mammary gland5 / 15327132
mouth1 / 6705214
muscle9 / 10771583
nerve2 / 15768126
ovary4 / 10205139
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta8 / 28082528
prostate0 / 1893450 
salivary gland3 / 20155148
skin6 / 21057428
spleen0 / 539520 
stomach2 / 9661920
testis28 / 33044284
thymus9 / 81131110
thyroid7 / 47473147
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord2 / 13680146
uterus10 / 23287842
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203346_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts74.55
Adipocyte4.65
AdrenalCortex6.95
Adrenalgland3.95
Amygdala4.5
Appendix4.8
AtrioventricularNode3.75
BDCA4+_DentriticCells64.6
Bonemarrow4.75
BronchialEpithelialCells4.6
CD105+_Endothelial75.45
CD14+_Monocytes26.65
CD19+_BCells(neg._sel.)172.8
CD33+_Myeloid50.7
CD34+237.8
CD4+_Tcells82.2
CD56+_NKCells84.5
CD71+_EarlyErythroid29.7
CD8+_Tcells100.6
CardiacMyocytes5.8
Caudatenucleus3.9
Cerebellum3.75
CerebellumPeduncles5.45
CiliaryGanglion3.45
CingulateCortex4.85
Colorectaladenocarcinoma4.6
DorsalRootGanglion3.65
FetalThyroid7.8
Fetalbrain4.95
Fetalliver7.75
Fetallung3.95
GlobusPallidus3.45
Heart6.25
Hypothalamus5.15
Kidney3.65
Leukemia_chronicMyelogenousK-5625.65
Leukemia_promyelocytic-HL-604.2
Leukemialymphoblastic(MOLT-4)46
Liver6
Lung4.9
Lymphnode3.85
Lymphoma_burkitts(Daudi)16.9
Lymphoma_burkitts(Raji)6.6
MedullaOblongata4.25
OccipitalLobe4.25
OlfactoryBulb3.7
Ovary3.15
Pancreas3.9
PancreaticIslet5.05
ParietalLobe5.05
Pituitary6.3
Placenta4.45
Pons4.05
PrefrontalCortex16.4
Prostate5.5
Salivarygland3.7
SkeletalMuscle5.75
Skin3.5
SmoothMuscle4.85
Spinalcord4.55
SubthalamicNucleus4.25
SuperiorCervicalGanglion5.6
TemporalLobe4.3
Testis4
TestisGermCell60.75
TestisIntersitial9.2
TestisLeydigCell4.7
TestisSeminiferousTubule22.45
Thalamus4.55
Thymus13.95
Thyroid5.9
Tongue4.7
Tonsil25.6
Trachea3.9
TrigeminalGanglion4.6
Uterus6.7
UterusCorpus4
WholeBlood13.85
Wholebrain3.65
colon4.5
pineal_day6.04
pineal_night6.1
retina5.225
small_intestine4.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_2197_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.8 ± 0.32
Basal Forebrain8.61 ± 0.11
Basal Part of Pons8.22 ± 0.19
Cerebellar Cortex8.72 ± 0.12
Cerebellar Nuclei8.11 ± 0.31
Claustrum8.77 ± 0.59
Epithalamus8.45 ± 0.15
Frontal Lobe8.24 ± 0.24
Globus Pallidus8.06 ± 0.18
Hypothalamus8.31 ± 0.24
Insula8.37 ± 0.13
Limbic Lobe8.54 ± 0.33
Mesencephalon8.37 ± 0.29
Myelencephalon8.37 ± 0.26
Occipital Lobe8.58 ± 0.26
Parietal Lobe8.43 ± 0.29
Pontine Tegmentum8.3 ± 0.28
Striatum8.48 ± 0.35
Subthalamus8.25 ± 0.11
Temporal Lobe8.41 ± 0.31
Thalamus8.18 ± 0.21
White Matter8.73 ± 0.16
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mtf2CBCerebellum3.03
2.71
Mtf2CTXCerebral cortex17.62
8.99
Mtf2HIPHippocampal region29.14
14.28
Mtf2HPFHippocampal formation27.03
13.35
Mtf2HYHypothalamus5.87
2.97
Mtf2LSXLateral septal complex9.57
5
Mtf2MBMidbrain6.9
3.92
Mtf2MYMedulla12.86
8.29
Mtf2OLFOlfactory bulb35.28
17.43
Mtf2PPons11.63
7.35
Mtf2PALPallidum5.32
3.13
Mtf2RHPRetrohippocampal region22.23
11.49
Mtf2sAMYStriatum-like amygdalar nuclei9.19
4.4
Mtf2STRStriatum7.96
3.71
Mtf2STRdStriatum dorsal region5.25
2.47
Mtf2STRvStriatum ventral region15.2
6.19
Mtf2THThalamus5.92
3.03
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000473 17 39 55 AKKPACKFEEGQDVLAR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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