Annotation Detail for HSPA4L
Basic Information Top
| Gene Symbol: | HSPA4L ( APG-1,Osp94 ) |
|---|---|
| Gene Full Name: | heat shock 70kDa protein 4-like |
| Band: | 4q28.1 |
| Quick Links | Entrez ID:22824; OMIM: NA; Uniprot ID:HS74L_HUMAN; ENSEMBL ID: ENSG00000164070; HGNC ID: 17041 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.135554
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 12 / 564012 | 21 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 1 / 23620 | 42 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 31 / 1939121 | 15 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 1 / 94178 | 10 |  |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 1 / 17290 | 57 |  |
| gastrointestinal tumor | 1 / 119369 | 8 | |
| germ cell tumor | 6 / 263845 | 22 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 3 / 136302 | 22 | |
| kidney tumor | 2 / 68959 | 29 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 2 / 96359 | 20 | |
| lung tumor | 4 / 103127 | 38 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 100 / 3360307 | 29 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 2 / 125680 | 15 | |
| prostate cancer | 5 / 102680 | 48 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 4 / 125191 | 31 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 2 / 29757 | 67 | |
| blood | 1 / 123478 | 8 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 38 / 1100989 | 34 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 1 / 149255 | 6 | |
| ear | 3 / 16212 | 185 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 5 / 211054 | 23 | |
| heart | 1 / 89626 | 11 | |
| intestine | 1 / 234472 | 4 | |
| kidney | 11 / 211777 | 51 | |
| larynx | 0 / 24145 | 0 | |
| liver | 3 / 207743 | 14 | |
| lung | 9 / 336974 | 26 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 1 / 153271 | 6 | |
| mouth | 2 / 67052 | 29 | |
| muscle | 5 / 107715 | 46 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 1 / 20539 | 48 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 3 / 280825 | 10 | |
| prostate | 6 / 189345 | 31 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 77 / 330442 | 233 |  |
| thymus | 1 / 81131 | 12 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 8 / 52413 | 152 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 4 / 232878 | 17 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 205543_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 86.45 | |
| Adipocyte | 4.05 | |
| AdrenalCortex | 4.55 | |
| Adrenalgland | 3.5 | |
| Amygdala | 5.45 | |
| Appendix | 4.25 | |
| AtrioventricularNode | 3.3 | |
| BDCA4+_DentriticCells | 4.4 | |
| Bonemarrow | 4.15 | |
| BronchialEpithelialCells | 7.95 | |
| CD105+_Endothelial | 4.3 | |
| CD14+_Monocytes | 4.35 | |
| CD19+_BCells(neg._sel.) | 4.35 | |
| CD33+_Myeloid | 5.3 | |
| CD34+ | 5.35 | |
| CD4+_Tcells | 4.5 | |
| CD56+_NKCells | 4.8 | |
| CD71+_EarlyErythroid | 3.9 | |
| CD8+_Tcells | 4 | |
| CardiacMyocytes | 5.45 | |
| Caudatenucleus | 3.7 | |
| Cerebellum | 3.35 | |
| CerebellumPeduncles | 4.65 | |
| CiliaryGanglion | 3.15 | |
| CingulateCortex | 4.25 | |
| Colorectaladenocarcinoma | 4.1 | |
| DorsalRootGanglion | 3.25 | |
| FetalThyroid | 3.95 | |
| Fetalbrain | 4.1 | |
| Fetalliver | 3.55 | |
| Fetallung | 3.3 | |
| GlobusPallidus | 3.15 | |
| Heart | 5.4 | |
| Hypothalamus | 4.9 | |
| Kidney | 3.35 | |
| Leukemia_chronicMyelogenousK-562 | 3.75 | |
| Leukemia_promyelocytic-HL-60 | 3.6 | |
| Leukemialymphoblastic(MOLT-4) | 3.35 | |
| Liver | 5.45 | |
| Lung | 4.4 | |
| Lymphnode | 3.5 | |
| Lymphoma_burkitts(Daudi) | 5.25 | |
| Lymphoma_burkitts(Raji) | 5.7 | |
| MedullaOblongata | 4.1 | |
| OccipitalLobe | 3.7 | |
| OlfactoryBulb | 3.2 | |
| Ovary | 2.75 | |
| Pancreas | 3.3 | |
| PancreaticIslet | 4.4 | |
| ParietalLobe | 4.4 | |
| Pituitary | 5.15 | |
| Placenta | 4.2 | |
| Pons | 3.95 | |
| PrefrontalCortex | 5.25 | |
| Prostate | 4.7 | |
| Salivarygland | 3.3 | |
| SkeletalMuscle | 5.25 | |
| Skin | 3.65 | |
| SmoothMuscle | 4.6 | |
| Spinalcord | 4.4 | |
| SubthalamicNucleus | 3.9 | |
| SuperiorCervicalGanglion | 4.75 | |
| TemporalLobe | 3.75 | |
| Testis | 38.6 | |
| TestisGermCell | 190 | |
| TestisIntersitial | 346.65 | |
| TestisLeydigCell | 184.05 | |
| TestisSeminiferousTubule | 129.65 | |
| Thalamus | 4.3 | |
| Thymus | 3.15 | |
| Thyroid | 5.05 | |
| Tongue | 4.1 | |
| Tonsil | 4 | |
| Trachea | 3.4 | |
| TrigeminalGanglion | 5 | |
| Uterus | 3.35 | |
| UterusCorpus | 3.75 | |
| WholeBlood | 4.45 | |
| Wholebrain | 3.45 | |
| colon | 4.15 | |
| pineal_day | 32.92 | |
| pineal_night | 29.9 | |
| retina | 4.9 | |
| small_intestine | 3.9 | |
- Probe name: CUST_752_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 8.74 ± 0.34 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 8.52 ± 0.22 | |
| Basal Part of Pons | 9.15 ± 0.23 | |
| Cerebellar Cortex | 8.94 ± 0.39 | |
| Cerebellar Nuclei | 9.42 ± 0.4 | |
| Claustrum | 8.63 ± 0.54 | |
| Epithalamus | 8.49 ± 0.29 | |
| Frontal Lobe | 8.84 ± 0.43 | |
| Globus Pallidus | 8.9 ± 0.28 | |
| Hypothalamus | 9.03 ± 0.39 | |
| Insula | 8.7 ± 0.21 | |
| Limbic Lobe | 8.94 ± 0.41 | |
| Mesencephalon | 9.01 ± 0.53 | |
| Myelencephalon | 8.84 ± 0.43 | |
| Occipital Lobe | 9.35 ± 0.33 | |
| Parietal Lobe | 9.07 ± 0.35 | |
| Pontine Tegmentum | 8.87 ± 0.32 | |
| Striatum | 8.38 ± 0.29 | |
| Subthalamus | 9.49 ± 0.21 | |
| Temporal Lobe | 8.75 ± 0.33 | |
| Thalamus | 8.99 ± 0.28 | |
| White Matter | 7.19 ± 0.3 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Hspa4l | CB | Cerebellum | 55.01 | |
| 100 | | |||
| Hspa4l | CTX | Cerebral cortex | 100 | |
| 100 | | |||
| Hspa4l | HIP | Hippocampal region | 85.91 | |
| 100 | | |||
| Hspa4l | HPF | Hippocampal formation | 100 | |
| 100 | | |||
| Hspa4l | HY | Hypothalamus | 100 | |
| 100 | | |||
| Hspa4l | LSX | Lateral septal complex | 100 | |
| 100 | | |||
| Hspa4l | MB | Midbrain | 100 | |
| 100 | | |||
| Hspa4l | MY | Medulla | 100 | |
| 100 | | |||
| Hspa4l | OLF | Olfactory bulb | 100 | |
| 100 | | |||
| Hspa4l | P | Pons | 100 | |
| 100 | | |||
| Hspa4l | PAL | Pallidum | 100 | |
| 100 | | |||
| Hspa4l | RHP | Retrohippocampal region | 100 | |
| 100 | | |||
| Hspa4l | sAMY | Striatum-like amygdalar nuclei | 100 | |
| 100 | | |||
| Hspa4l | STR | Striatum | 100 | |
| 92.56 | | |||
| Hspa4l | STRd | Striatum dorsal region | 100 | |
| 87.61 | | |||
| Hspa4l | STRv | Striatum ventral region | 100 | |
| 90.54 | | |||
| Hspa4l | TH | Thalamus | 100 | |
| 100 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| HS74L_HUMAN_20 | 14 | 20 | 33 | SGGIETIANEYSDR | PRIDE |
| HS74L_HUMAN_726 | 11 | 726 | 736 | YDHLDPTEMEK | PRIDE |
| HS74L_HUMAN_74 | 11 | 74 | 84 | SFDDPIVQTER | PRIDE |
| PAp00001045 | 17 | 540 | 556 | CHAEHTPEEEIDHTGAK | Peptide Atlas |