AutismKB 2.0

Annotation Detail for NLGN4Y


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Basic Information Top
Gene Symbol:NLGN4Y ( KIAA0951 )
Gene Full Name: neuroligin 4, Y-linked
Band: Yq11.221
Quick LinksEntrez ID:22829; OMIM: 400028; Uniprot ID:NLGNY_HUMAN; ENSEMBL ID: ENSG00000165246; HGNC ID: 15529
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus3 / 5640125
neonate3 / 3109796
infant0 / 236200 
juvenile1 / 5555617
adult16 / 19391218
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal33 / 33603079
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain12 / 110098910
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine0 / 2344720 
kidney4 / 21177718
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta0 / 2808250 
prostate3 / 18934515
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord2 / 13680146
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207703_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.2
Adipocyte6.2
AdrenalCortex7.65
Adrenalgland5.7
Amygdala6.6
Appendix7.85
AtrioventricularNode7.25
BDCA4+_DentriticCells6.6
Bonemarrow7.6
BronchialEpithelialCells6.05
CD105+_Endothelial6.35
CD14+_Monocytes6.8
CD19+_BCells(neg._sel.)6.5
CD33+_Myeloid7.85
CD34+7.6
CD4+_Tcells6.5
CD56+_NKCells7.15
CD71+_EarlyErythroid6.3
CD8+_Tcells5.75
CardiacMyocytes14.05
Caudatenucleus5.75
Cerebellum5.3
CerebellumPeduncles7.95
CiliaryGanglion5.45
CingulateCortex6.75
Colorectaladenocarcinoma6.35
DorsalRootGanglion5.95
FetalThyroid6.5
Fetalbrain6.15
Fetalliver5.7
Fetallung4.9
GlobusPallidus5.55
Heart12.4
Hypothalamus7.2
Kidney5.75
Leukemia_chronicMyelogenousK-5625.7
Leukemia_promyelocytic-HL-605.6
Leukemialymphoblastic(MOLT-4)4.9
Liver9.45
Lung6.95
Lymphnode5.25
Lymphoma_burkitts(Daudi)8.4
Lymphoma_burkitts(Raji)9.95
MedullaOblongata5.75
OccipitalLobe5.75
OlfactoryBulb4.95
Ovary4.65
Pancreas5.35
PancreaticIslet7
ParietalLobe7.5
Pituitary7.4
Placenta6.35
Pons6.45
PrefrontalCortex7.6
Prostate7.3
Salivarygland5.45
SkeletalMuscle8.95
Skin6.25
SmoothMuscle7.2
Spinalcord6.65
SubthalamicNucleus6.15
SuperiorCervicalGanglion9.2
TemporalLobe6.4
Testis5.45
TestisGermCell5.1
TestisIntersitial5.6
TestisLeydigCell6.65
TestisSeminiferousTubule5.4
Thalamus6.65
Thymus4.8
Thyroid7.75
Tongue7.6
Tonsil6.4
Trachea5.3
TrigeminalGanglion8.75
Uterus5.05
UterusCorpus6.45
WholeBlood6.9
Wholebrain5.35
colon6.45
pineal_day8.94
pineal_night8.46
retina7.85
small_intestine6.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P33903
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.81 ± 0.47
Basal Forebrain6.86 ± 0.25
Basal Part of Pons6.72 ± 0.46
Cerebellar Cortex6.86 ± 0.29
Cerebellar Nuclei6.76 ± 0.36
Claustrum6.56 ± 0.41
Epithalamus6.39 ± 0.46
Frontal Lobe6.93 ± 0.39
Globus Pallidus6.16 ± 0.33
Hypothalamus6.95 ± 0.39
Insula7.05 ± 0.23
Limbic Lobe7.13 ± 0.42
Mesencephalon6.82 ± 0.45
Myelencephalon6.84 ± 0.42
Occipital Lobe7.04 ± 0.4
Parietal Lobe6.93 ± 0.4
Pontine Tegmentum6.98 ± 0.38
Striatum6.74 ± 0.43
Subthalamus6.75 ± 0.54
Temporal Lobe6.99 ± 0.35
Thalamus6.9 ± 0.33
White Matter6.52 ± 0.24
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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