AutismKB 2.0

Annotation Detail for ADNP2


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Basic Information Top
Gene Symbol:ADNP2 ( KIAA0863,ZNF508 )
Gene Full Name: ADNP homeobox 2
Band: 18q23
Quick LinksEntrez ID:22850; OMIM: NA; Uniprot ID:ADNP2_HUMAN; ENSEMBL ID: ENSG00000101544; HGNC ID: 23803
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst8 / 62319128
fetus32 / 56401256
neonate0 / 310970 
infant0 / 236200 
juvenile5 / 5555689
adult55 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor4 / 34366116
chondrosarcoma4 / 8282348
colorectal tumor2 / 11424617
esophageal tumor1 / 1729057
gastrointestinal tumor5 / 11936941
germ cell tumor21 / 26384579
glioma2 / 10688318
head and neck tumor3 / 13630222
kidney tumor4 / 6895958
leukemia0 / 958420 
liver tumor7 / 9635972
lung tumor1 / 1031279
lymphoma3 / 7175541
non-neoplasia2 / 9725020
normal128 / 336030738
ovarian tumor4 / 7668252
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer5 / 10268048
retinoblastoma2 / 4635643
skin tumor3 / 12494924
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites2 / 4001549
bladder0 / 297570 
blood2 / 12347816
bone3 / 7165541
bone marrow0 / 488010 
brain15 / 110098913
cervix4 / 4817183
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue22 / 215722101
esophagus1 / 2020949
eye10 / 21105447
heart2 / 8962622
intestine5 / 23447221
kidney5 / 21177723
larynx0 / 241450 
liver12 / 20774357
lung10 / 33697429
lymph0 / 442700 
lymph node13 / 91610141
mammary gland7 / 15327145
mouth2 / 6705229
muscle6 / 10771555
nerve0 / 157680 
ovary4 / 10205139
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta9 / 28082532
prostate6 / 18934531
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach3 / 9661931
testis21 / 33044263
thymus0 / 811310 
thyroid3 / 4747363
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord1 / 1368073
uterus12 / 23287851
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203322_at
Cell line Expression level Expression bar
721_B_lymphoblasts58.4
Adipocyte6.3
AdrenalCortex7.3
Adrenalgland5.9
Amygdala7.35
Appendix7.15
AtrioventricularNode5.1
BDCA4+_DentriticCells18
Bonemarrow7
BronchialEpithelialCells8.4
CD105+_Endothelial37.05
CD14+_Monocytes9.75
CD19+_BCells(neg._sel.)31.15
CD33+_Myeloid18.05
CD34+63.85
CD4+_Tcells30.1
CD56+_NKCells32.35
CD71+_EarlyErythroid7.9
CD8+_Tcells51.35
CardiacMyocytes8.8
Caudatenucleus6.1
Cerebellum5.5
CerebellumPeduncles7.9
CiliaryGanglion4.85
CingulateCortex7.15
Colorectaladenocarcinoma6.95
DorsalRootGanglion5.4
FetalThyroid6.75
Fetalbrain7.05
Fetalliver5.8
Fetallung5.8
GlobusPallidus5.15
Heart8.65
Hypothalamus8.3
Kidney5.6
Leukemia_chronicMyelogenousK-5626.4
Leukemia_promyelocytic-HL-606.65
Leukemialymphoblastic(MOLT-4)24.3
Liver9.15
Lung7.25
Lymphnode6.05
Lymphoma_burkitts(Daudi)8.4
Lymphoma_burkitts(Raji)9.85
MedullaOblongata5.75
OccipitalLobe6.3
OlfactoryBulb5.3
Ovary4.65
Pancreas5.6
PancreaticIslet7.1
ParietalLobe7.6
Pituitary8.15
Placenta7.5
Pons6.35
PrefrontalCortex8.85
Prostate8.25
Salivarygland5.55
SkeletalMuscle8.1
Skin5.2
SmoothMuscle7.7
Spinalcord7.25
SubthalamicNucleus6.35
SuperiorCervicalGanglion7.85
TemporalLobe6.35
Testis24.05
TestisGermCell42.35
TestisIntersitial12
TestisLeydigCell8.9
TestisSeminiferousTubule10.55
Thalamus7
Thymus7.55
Thyroid8.8
Tongue6.75
Tonsil6.4
Trachea5.85
TrigeminalGanglion7
Uterus5.8
UterusCorpus6.25
WholeBlood8.25
Wholebrain5.65
colon7.5
pineal_day23.78
pineal_night17.08
retina14.125
small_intestine7.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7445_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.78 ± 0.38
Basal Forebrain5.85 ± 0.16
Basal Part of Pons5.62 ± 0.5
Cerebellar Cortex5.69 ± 0.38
Cerebellar Nuclei5.71 ± 0.38
Claustrum5.74 ± 0.66
Epithalamus5.81 ± 0.23
Frontal Lobe5.71 ± 0.35
Globus Pallidus5.8 ± 0.23
Hypothalamus5.81 ± 0.3
Insula5.68 ± 0.29
Limbic Lobe5.71 ± 0.34
Mesencephalon5.74 ± 0.41
Myelencephalon5.77 ± 0.41
Occipital Lobe5.89 ± 0.36
Parietal Lobe5.86 ± 0.35
Pontine Tegmentum5.8 ± 0.36
Striatum5.72 ± 0.32
Subthalamus5.64 ± 0.27
Temporal Lobe5.78 ± 0.32
Thalamus5.87 ± 0.4
White Matter6.82 ± 0.32
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfp508CBCerebellum4.4
4.89
Zfp508CTXCerebral cortex12.25
8.76
Zfp508HIPHippocampal region19.18
19.2
Zfp508HPFHippocampal formation18.81
16.67
Zfp508HYHypothalamus1.26
0.97
Zfp508LSXLateral septal complex0.6
0.37
Zfp508MBMidbrain2.33
2.51
Zfp508MYMedulla0.95
1.34
Zfp508OLFOlfactory bulb5.39
4.69
Zfp508PPons2.39
4
Zfp508PALPallidum2.31
1.79
Zfp508RHPRetrohippocampal region18.56
13.41
Zfp508sAMYStriatum-like amygdalar nuclei4.3
2.87
Zfp508STRStriatum2.02
1.34
Zfp508STRdStriatum dorsal region1.66
1.1
Zfp508STRvStriatum ventral region3.33
2.11
Zfp508THThalamus6.65
5.3
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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