AutismKB 2.0

Annotation Detail for FASTKD2


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Basic Information Top
Gene Symbol:FASTKD2 ( KIAA0971 )
Gene Full Name: FAST kinase domains 2
Band: 2q33.3
Quick LinksEntrez ID:22868; OMIM: 612322; Uniprot ID:FAKD2_HUMAN; ENSEMBL ID: ENSG00000118246; HGNC ID: 29160
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst3 / 6231948
fetus35 / 56401262
neonate6 / 31097192
infant5 / 23620211
juvenile9 / 55556161
adult123 / 193912163
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor10 / 94178106
cervical tumor0 / 343660 
chondrosarcoma8 / 8282396
colorectal tumor6 / 11424652
esophageal tumor4 / 17290231
gastrointestinal tumor11 / 11936992
germ cell tumor31 / 263845117
glioma5 / 10688346
head and neck tumor15 / 136302110
kidney tumor4 / 6895958
leukemia7 / 9584273
liver tumor7 / 9635972
lung tumor4 / 10312738
lymphoma5 / 7175569
non-neoplasia4 / 9725041
normal249 / 336030774
ovarian tumor8 / 76682104
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS11 / 12568087
prostate cancer3 / 10268029
retinoblastoma2 / 4635643
skin tumor4 / 12494932
soft tissue/muscle tissue tumor13 / 125191103
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites3 / 4001574
bladder2 / 2975767
blood6 / 12347848
bone4 / 7165555
bone marrow7 / 48801143
brain85 / 110098977
cervix0 / 481710 
connective tissue19 / 149255127
ear0 / 162120 
embryonic tissue21 / 21572297
esophagus4 / 20209197
eye4 / 21105418
heart4 / 8962644
intestine17 / 23447272
kidney18 / 21177784
larynx0 / 241450 
liver9 / 20774343
lung16 / 33697447
lymph5 / 44270112
lymph node7 / 9161076
mammary gland10 / 15327165
mouth7 / 67052104
muscle7 / 10771564
nerve3 / 15768190
ovary8 / 10205178
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx9 / 41328217
pituitary gland0 / 165850 
placenta31 / 280825110
prostate9 / 18934547
salivary gland0 / 201550 
skin14 / 21057466
spleen6 / 53952111
stomach9 / 9661993
testis21 / 33044263
thymus5 / 8113161
thyroid5 / 47473105
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord1 / 1368073
uterus15 / 23287864
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 216996_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts65.9
Adipocyte8.3
AdrenalCortex9
Adrenalgland7.05
Amygdala9.3
Appendix10.5
AtrioventricularNode7.3
BDCA4+_DentriticCells19.1
Bonemarrow8.1
BronchialEpithelialCells35.1
CD105+_Endothelial34.1
CD14+_Monocytes10.1
CD19+_BCells(neg._sel.)16.45
CD33+_Myeloid27.9
CD34+14.8
CD4+_Tcells25.8
CD56+_NKCells10.55
CD71+_EarlyErythroid7.85
CD8+_Tcells15.4
CardiacMyocytes14.05
Caudatenucleus7.15
Cerebellum6.55
CerebellumPeduncles9.3
CiliaryGanglion6.15
CingulateCortex8.05
Colorectaladenocarcinoma9.05
DorsalRootGanglion7.1
FetalThyroid8.4
Fetalbrain7.7
Fetalliver7.35
Fetallung6.95
GlobusPallidus6.35
Heart10.85
Hypothalamus8.9
Kidney6.75
Leukemia_chronicMyelogenousK-56216.05
Leukemia_promyelocytic-HL-6014.5
Leukemialymphoblastic(MOLT-4)10.45
Liver11.3
Lung8.4
Lymphnode8.35
Lymphoma_burkitts(Daudi)18.45
Lymphoma_burkitts(Raji)12.35
MedullaOblongata7.1
OccipitalLobe7.5
OlfactoryBulb6.8
Ovary6.6
Pancreas11.15
PancreaticIslet9.4
ParietalLobe9.45
Pituitary10.75
Placenta7.65
Pons7.8
PrefrontalCortex10.45
Prostate9
Salivarygland8.5
SkeletalMuscle10
Skin6.85
SmoothMuscle12
Spinalcord8.6
SubthalamicNucleus7.35
SuperiorCervicalGanglion9.85
TemporalLobe7.6
Testis7.1
TestisGermCell6.95
TestisIntersitial7.75
TestisLeydigCell10.15
TestisSeminiferousTubule7
Thalamus8.45
Thymus5.7
Thyroid10.75
Tongue8.75
Tonsil8
Trachea7.55
TrigeminalGanglion6.35
Uterus8.25
UterusCorpus7.7
WholeBlood9.4
Wholebrain6.1
colon8.75
pineal_day12.78
pineal_night12.62
retina9.75
small_intestine8.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P209649
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.19 ± 0.36
Basal Forebrain5.23 ± 0.37
Basal Part of Pons5.59 ± 0.2
Cerebellar Cortex5.38 ± 0.26
Cerebellar Nuclei5.17 ± 0.54
Claustrum5.27 ± 0.41
Epithalamus5.15 ± 0.44
Frontal Lobe5.28 ± 0.36
Globus Pallidus4.27 ± 0.41
Hypothalamus5.26 ± 0.64
Insula5.34 ± 0.25
Limbic Lobe5.23 ± 0.54
Mesencephalon5.18 ± 0.39
Myelencephalon5.15 ± 0.49
Occipital Lobe5.07 ± 0.51
Parietal Lobe5.23 ± 0.35
Pontine Tegmentum5.14 ± 0.44
Striatum4.97 ± 0.46
Subthalamus5.82 ± 0.1
Temporal Lobe5.36 ± 0.36
Thalamus5.09 ± 0.47
White Matter4.6 ± 0.3
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fastkd2CBCerebellum10.54
10.71
Fastkd2CTXCerebral cortex12.65
8.54
Fastkd2HIPHippocampal region12.47
11.46
Fastkd2HPFHippocampal formation12.92
10.2
Fastkd2HYHypothalamus7.79
5.07
Fastkd2LSXLateral septal complex10.38
6.35
Fastkd2MBMidbrain9.33
7.87
Fastkd2MYMedulla18.36
17.29
Fastkd2OLFOlfactory bulb19.45
12.81
Fastkd2PPons11.37
10.49
Fastkd2PALPallidum7.2
5.59
Fastkd2RHPRetrohippocampal region13.95
8.77
Fastkd2sAMYStriatum-like amygdalar nuclei2.58
1.59
Fastkd2STRStriatum4.43
2.9
Fastkd2STRdStriatum dorsal region3.4
2.31
Fastkd2STRvStriatum ventral region8.77
5.39
Fastkd2THThalamus7.54
7.26
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00075688 19 615 633 NQVLPLSDVDTTSATDIQR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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