AutismKB 2.0

Annotation Detail for INPP5F


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Basic Information Top
Gene Symbol:INPP5F ( FLJ13081,KIAA0966,MGC131851,MGC59773,MSTPO47,SAC2,hSAC2 )
Gene Full Name: inositol polyphosphate-5-phosphatase F
Band: 10q26.11
Quick LinksEntrez ID:22876; OMIM: 609389; Uniprot ID:SAC2_HUMAN; ENSEMBL ID: ENSG00000198825; HGNC ID: 17054
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body13 / 70761183
blastocyst21 / 62319336
fetus43 / 56401276
neonate0 / 310970 
infant0 / 236200 
juvenile4 / 5555671
adult63 / 193912132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor4 / 26384515
glioma4 / 10688337
head and neck tumor7 / 13630251
kidney tumor4 / 6895958
leukemia4 / 9584241
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia8 / 9725082
normal204 / 336030760
ovarian tumor4 / 7668252
pancreatic tumor12 / 104616114
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor15 / 124949120
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder2 / 2975767
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain91 / 110098982
cervix1 / 4817120
connective tissue4 / 14925526
ear1 / 1621261
embryonic tissue45 / 215722208
esophagus1 / 2020949
eye16 / 21105475
heart1 / 8962611
intestine4 / 23447217
kidney5 / 21177723
larynx1 / 2414541
liver0 / 2077430 
lung4 / 33697411
lymph0 / 442700 
lymph node4 / 9161043
mammary gland2 / 15327113
mouth0 / 670520 
muscle1 / 1077159
nerve3 / 15768190
ovary4 / 10205139
pancreas14 / 21481265
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta5 / 28082517
prostate6 / 18934531
salivary gland0 / 201550 
skin22 / 210574104
spleen0 / 539520 
stomach1 / 9661910
testis16 / 33044248
thymus2 / 8113124
thyroid6 / 47473126
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus8 / 23287834
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203607_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.6
Adipocyte10.2
AdrenalCortex14.85
Adrenalgland9.15
Amygdala542.6
Appendix13.5
AtrioventricularNode15.95
BDCA4+_DentriticCells26.7
Bonemarrow11.05
BronchialEpithelialCells9.75
CD105+_Endothelial14.45
CD14+_Monocytes11.15
CD19+_BCells(neg._sel.)50.95
CD33+_Myeloid15.75
CD34+21.4
CD4+_Tcells18.4
CD56+_NKCells19.4
CD71+_EarlyErythroid16.7
CD8+_Tcells12.2
CardiacMyocytes24.8
Caudatenucleus338.55
Cerebellum125.55
CerebellumPeduncles240
CiliaryGanglion15.2
CingulateCortex552
Colorectaladenocarcinoma14.6
DorsalRootGanglion18.95
FetalThyroid11.05
Fetalbrain507.55
Fetalliver10.8
Fetallung11.4
GlobusPallidus235.6
Heart13.85
Hypothalamus1836.85
Kidney9.15
Leukemia_chronicMyelogenousK-5629.65
Leukemia_promyelocytic-HL-6013.5
Leukemialymphoblastic(MOLT-4)8.65
Liver15.1
Lung11.3
Lymphnode20.85
Lymphoma_burkitts(Daudi)14
Lymphoma_burkitts(Raji)27.8
MedullaOblongata507.15
OccipitalLobe454.2
OlfactoryBulb113.15
Ovary7.5
Pancreas8.6
PancreaticIslet136.25
ParietalLobe421.3
Pituitary245.05
Placenta16.9
Pons249.95
PrefrontalCortex1239.45
Prostate18.45
Salivarygland10.85
SkeletalMuscle14.2
Skin11.2
SmoothMuscle17.1
Spinalcord370.6
SubthalamicNucleus510.3
SuperiorCervicalGanglion22
TemporalLobe240.75
Testis9.8
TestisGermCell14
TestisIntersitial10.35
TestisLeydigCell14.2
TestisSeminiferousTubule11.95
Thalamus761.75
Thymus11.3
Thyroid36.05
Tongue13.75
Tonsil19.75
Trachea11.15
TrigeminalGanglion18.45
Uterus26.05
UterusCorpus12.3
WholeBlood9.9
Wholebrain298.6
colon25.2
pineal_day64.1
pineal_night74.18
retina52.325
small_intestine12.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P35684
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.73 ± 0.26
Basal Forebrain11.06 ± 0.33
Basal Part of Pons11.55 ± 0.24
Cerebellar Cortex10.55 ± 0.28
Cerebellar Nuclei11.21 ± 0.28
Claustrum10.94 ± 0.49
Epithalamus9.99 ± 0.94
Frontal Lobe10.8 ± 0.46
Globus Pallidus10.38 ± 0.66
Hypothalamus11.32 ± 0.24
Insula10.74 ± 0.33
Limbic Lobe10.76 ± 0.58
Mesencephalon10.93 ± 0.48
Myelencephalon10.85 ± 0.54
Occipital Lobe11.45 ± 0.37
Parietal Lobe11.05 ± 0.42
Pontine Tegmentum10.85 ± 0.35
Striatum10.87 ± 0.37
Subthalamus11.73 ± 0.36
Temporal Lobe10.76 ± 0.39
Thalamus11.04 ± 0.34
White Matter8.88 ± 0.52
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Inpp5fCBCerebellum34.27
38.37
Inpp5fCTXCerebral cortex50.63
40.75
Inpp5fHIPHippocampal region38.75
55.43
Inpp5fHPFHippocampal formation48.95
56
Inpp5fHYHypothalamus76.48
69.03
Inpp5fLSXLateral septal complex67.44
56.57
Inpp5fMBMidbrain69.64
69.21
Inpp5fMYMedulla78.62
92.58
Inpp5fOLFOlfactory bulb47.7
41.07
Inpp5fPPons71.65
84.5
Inpp5fPALPallidum77.66
84.96
Inpp5fRHPRetrohippocampal region64.59
57.26
Inpp5fsAMYStriatum-like amygdalar nuclei86.39
79.94
Inpp5fSTRStriatum77.12
61.43
Inpp5fSTRdStriatum dorsal region74.2
58.15
Inpp5fSTRvStriatum ventral region87.02
65.92
Inpp5fTHThalamus38.02
36.3
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00500691 27 905 931 SQSLSSTDSSVHAPSEITVAHGSGLGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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