AutismKB 2.0

Annotation Detail for TRAPPC8


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Basic Information Top
Gene Symbol:TRAPPC8 ( GSG1,HsT2706,KIAA1012,MGC71660,TRS85 )
Gene Full Name: trafficking protein particle complex 8
Band: 18q12.1
Quick LinksEntrez ID:22878; OMIM: NA; Uniprot ID:TPPC8_HUMAN; ENSEMBL ID: ENSG00000153339; HGNC ID: 29169
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst3 / 6231948
fetus13 / 56401223
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult88 / 193912145
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor3 / 26384511
glioma5 / 10688346
head and neck tumor6 / 13630244
kidney tumor3 / 6895943
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal129 / 336030738
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer6 / 10268058
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder4 / 29757134
blood0 / 1234780 
bone3 / 7165541
bone marrow2 / 4880140
brain30 / 110098927
cervix4 / 4817183
connective tissue8 / 14925553
ear1 / 1621261
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye6 / 21105428
heart1 / 8962611
intestine8 / 23447234
kidney13 / 21177761
larynx1 / 2414541
liver4 / 20774319
lung3 / 3369748
lymph0 / 442700 
lymph node5 / 9161054
mammary gland5 / 15327132
mouth4 / 6705259
muscle3 / 10771527
nerve4 / 15768253
ovary2 / 10205119
pancreas6 / 21481227
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta8 / 28082528
prostate8 / 18934542
salivary gland0 / 201550 
skin7 / 21057433
spleen0 / 539520 
stomach0 / 966190 
testis26 / 33044278
thymus5 / 8113161
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus11 / 23287847
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207305_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts274.25
Adipocyte32.8
AdrenalCortex17.35
Adrenalgland13.35
Amygdala74.15
Appendix23.85
AtrioventricularNode12.35
BDCA4+_DentriticCells433.15
Bonemarrow24.4
BronchialEpithelialCells29.05
CD105+_Endothelial175.15
CD14+_Monocytes252.3
CD19+_BCells(neg._sel.)448.35
CD33+_Myeloid277.55
CD34+156.95
CD4+_Tcells400
CD56+_NKCells424.9
CD71+_EarlyErythroid72.35
CD8+_Tcells326.7
CardiacMyocytes15.45
Caudatenucleus53.95
Cerebellum13.85
CerebellumPeduncles28.3
CiliaryGanglion14.45
CingulateCortex34.1
Colorectaladenocarcinoma10.35
DorsalRootGanglion18.55
FetalThyroid49.1
Fetalbrain77.35
Fetalliver30.25
Fetallung58.2
GlobusPallidus14.15
Heart18.95
Hypothalamus79.2
Kidney15.45
Leukemia_chronicMyelogenousK-56299.85
Leukemia_promyelocytic-HL-6076.65
Leukemialymphoblastic(MOLT-4)39.75
Liver26.75
Lung11.15
Lymphnode65.35
Lymphoma_burkitts(Daudi)42.3
Lymphoma_burkitts(Raji)91.45
MedullaOblongata39.6
OccipitalLobe49.65
OlfactoryBulb48.55
Ovary11.85
Pancreas14.3
PancreaticIslet45.65
ParietalLobe30.25
Pituitary91.35
Placenta19
Pons18.65
PrefrontalCortex149.95
Prostate41.25
Salivarygland22.5
SkeletalMuscle22.35
Skin16.2
SmoothMuscle34.35
Spinalcord37.25
SubthalamicNucleus23.35
SuperiorCervicalGanglion23.9
TemporalLobe18.2
Testis30.6
TestisGermCell190.6
TestisIntersitial83.4
TestisLeydigCell110.5
TestisSeminiferousTubule111.15
Thalamus39.65
Thymus33
Thyroid83.6
Tongue39.25
Tonsil55.75
Trachea34
TrigeminalGanglion19.35
Uterus53.6
UterusCorpus18
WholeBlood188.5
Wholebrain33.1
colon41.95
pineal_day313.58
pineal_night345.58
retina30.975
small_intestine29.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_679_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.95 ± 0.45
Basal Forebrain4.94 ± 0.44
Basal Part of Pons4.77 ± 0.59
Cerebellar Cortex5.28 ± 0.28
Cerebellar Nuclei4.94 ± 0.7
Claustrum4.47 ± 0.67
Epithalamus5.27 ± 0.33
Frontal Lobe4.91 ± 0.45
Globus Pallidus4.66 ± 0.38
Hypothalamus5 ± 0.37
Insula4.88 ± 0.4
Limbic Lobe4.82 ± 0.49
Mesencephalon4.92 ± 0.5
Myelencephalon4.83 ± 0.48
Occipital Lobe4.93 ± 0.46
Parietal Lobe4.83 ± 0.44
Pontine Tegmentum4.86 ± 0.44
Striatum4.66 ± 0.39
Subthalamus4.58 ± 0.27
Temporal Lobe4.95 ± 0.45
Thalamus4.78 ± 0.37
White Matter5.15 ± 0.38
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
D030074E01RikCBCerebellum37.16
50.61
D030074E01RikCTXCerebral cortex65.21
51.06
D030074E01RikHIPHippocampal region49.3
60.84
D030074E01RikHPFHippocampal formation58.07
59.59
D030074E01RikHYHypothalamus24.14
19.05
D030074E01RikLSXLateral septal complex35.09
25.9
D030074E01RikMBMidbrain33.43
31.91
D030074E01RikMYMedulla51.06
60.93
D030074E01RikOLFOlfactory bulb56.83
47.48
D030074E01RikPPons38.98
43.03
D030074E01RikPALPallidum34.3
32.4
D030074E01RikRHPRetrohippocampal region75.44
60.4
D030074E01RiksAMYStriatum-like amygdalar nuclei28.56
20.12
D030074E01RikSTRStriatum29.88
21.07
D030074E01RikSTRdStriatum dorsal region29.51
21.06
D030074E01RikSTRvStriatum ventral region30.56
20.38
D030074E01RikTHThalamus54.69
48.63
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
A8K922_HUMAN_350 9 350 358 QFIQEFTFR PRIDE
PAp00027607 16 538 553 SALLLEQAAHCFINMK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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