AutismKB 2.0

Annotation Detail for ANKRD6


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Basic Information Top
Gene Symbol:ANKRD6 ( - )
Gene Full Name: ankyrin repeat domain 6
Band: 6q15
Quick LinksEntrez ID:22881; OMIM: 610583; Uniprot ID:ANKR6_HUMAN; ENSEMBL ID: ENSG00000135299; HGNC ID: 17280
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst3 / 6231948
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult21 / 193912110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor7 / 26384526
glioma3 / 10688328
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal82 / 336030724
ovarian tumor1 / 7668213
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor9 / 12494972
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain44 / 110098939
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine0 / 2344720 
kidney5 / 21177723
larynx0 / 241450 
liver0 / 2077430 
lung9 / 33697426
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth2 / 6705229
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta2 / 2808257
prostate1 / 1893455
salivary gland1 / 2015549
skin9 / 21057442
spleen0 / 539520 
stomach0 / 966190 
testis18 / 33044254
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204671_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.6
Adipocyte8.1
AdrenalCortex9.9
Adrenalgland7.5
Amygdala32.8
Appendix12.8
AtrioventricularNode9.6
BDCA4+_DentriticCells7.3
Bonemarrow9.05
BronchialEpithelialCells9.1
CD105+_Endothelial7.7
CD14+_Monocytes9
CD19+_BCells(neg._sel.)8.35
CD33+_Myeloid10
CD34+9.55
CD4+_Tcells7.85
CD56+_NKCells9.55
CD71+_EarlyErythroid7.65
CD8+_Tcells7.2
CardiacMyocytes12.35
Caudatenucleus7.2
Cerebellum8.55
CerebellumPeduncles14.3
CiliaryGanglion7.7
CingulateCortex12.9
Colorectaladenocarcinoma7.9
DorsalRootGanglion8.85
FetalThyroid10.25
Fetalbrain17.05
Fetalliver7.6
Fetallung6.7
GlobusPallidus7.6
Heart16.75
Hypothalamus18.15
Kidney8.1
Leukemia_chronicMyelogenousK-5627.35
Leukemia_promyelocytic-HL-606.95
Leukemialymphoblastic(MOLT-4)5.95
Liver12.75
Lung10.1
Lymphnode7.5
Lymphoma_burkitts(Daudi)10.95
Lymphoma_burkitts(Raji)12.5
MedullaOblongata7.25
OccipitalLobe10.65
OlfactoryBulb6.65
Ovary8.1
Pancreas6.9
PancreaticIslet9.3
ParietalLobe9.95
Pituitary9.7
Placenta13.75
Pons8.35
PrefrontalCortex10.85
Prostate9.8
Salivarygland7.2
SkeletalMuscle16.15
Skin8.35
SmoothMuscle9.75
Spinalcord11.4
SubthalamicNucleus8.7
SuperiorCervicalGanglion15.55
TemporalLobe8.3
Testis8.6
TestisGermCell9.3
TestisIntersitial7.4
TestisLeydigCell9
TestisSeminiferousTubule7.2
Thalamus8.8
Thymus7.1
Thyroid12.95
Tongue11.75
Tonsil8.2
Trachea7
TrigeminalGanglion11.9
Uterus7.5
UterusCorpus9.55
WholeBlood9.35
Wholebrain16.55
colon7.85
pineal_day25.06
pineal_night28.5
retina18.625
small_intestine7.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_4872_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.83 ± 0.53
Basal Forebrain4.44 ± 0.44
Basal Part of Pons3.42 ± 0.71
Cerebellar Cortex4.87 ± 0.49
Cerebellar Nuclei3.66 ± 0.71
Claustrum3.81 ± 0.67
Epithalamus4.86 ± 0.7
Frontal Lobe4.44 ± 0.69
Globus Pallidus3.18 ± 0.4
Hypothalamus4.9 ± 0.68
Insula4.88 ± 0.25
Limbic Lobe4.47 ± 0.75
Mesencephalon4.52 ± 0.66
Myelencephalon4.29 ± 0.76
Occipital Lobe3.47 ± 0.79
Parietal Lobe3.91 ± 0.65
Pontine Tegmentum4.45 ± 0.71
Striatum3.26 ± 0.75
Subthalamus4.06 ± 0.52
Temporal Lobe4.68 ± 0.58
Thalamus3.98 ± 0.64
White Matter3.09 ± 0.8
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ankrd6CBCerebellum14.36
18.15
Ankrd6CTXCerebral cortex27.41
23.31
Ankrd6HIPHippocampal region27.54
41.4
Ankrd6HPFHippocampal formation29.72
36.53
Ankrd6HYHypothalamus19.6
15.44
Ankrd6LSXLateral septal complex15.64
13.93
Ankrd6MBMidbrain23.67
21.82
Ankrd6MYMedulla17.45
20.53
Ankrd6OLFOlfactory bulb39.19
35.7
Ankrd6PPons22.44
21.74
Ankrd6PALPallidum15.1
14.3
Ankrd6RHPRetrohippocampal region32.45
31.38
Ankrd6sAMYStriatum-like amygdalar nuclei24.48
17.67
Ankrd6STRStriatum15.97
11.84
Ankrd6STRdStriatum dorsal region14.36
10.71
Ankrd6STRvStriatum ventral region32.87
22.26
Ankrd6THThalamus18.7
16.54
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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