AutismKB 2.0

Annotation Detail for RALY


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Basic Information Top
Gene Symbol:RALY ( HNRPCL2,MGC117312,P542 )
Gene Full Name: RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))
Band: 20q11.22
Quick LinksEntrez ID:22913; OMIM: NA; Uniprot ID:RALY_HUMAN; ENSEMBL ID: ENSG00000125970; HGNC ID: 15921
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body18 / 70761254
blastocyst9 / 62319144
fetus68 / 564012120
neonate1 / 3109732
infant2 / 2362084
juvenile4 / 5555671
adult274 / 1939121141
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma0 / 174750 
breast (mammary gland) tumor14 / 94178148
cervical tumor7 / 34366203
chondrosarcoma9 / 82823108
colorectal tumor34 / 114246297
esophageal tumor0 / 172900 
gastrointestinal tumor45 / 119369376
germ cell tumor40 / 263845151
glioma37 / 106883346
head and neck tumor25 / 136302183
kidney tumor9 / 68959130
leukemia11 / 95842114
liver tumor16 / 96359166
lung tumor39 / 103127378
lymphoma10 / 71755139
non-neoplasia9 / 9725092
normal378 / 3360307112
ovarian tumor22 / 76682286
pancreatic tumor35 / 104616334
primitive neuroectodermal tumor of the CNS53 / 125680421
prostate cancer13 / 102680126
retinoblastoma7 / 46356151
skin tumor66 / 124949528
soft tissue/muscle tissue tumor40 / 125191319
uterine tumor14 / 90257155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland4 / 33197120
ascites22 / 40015549
bladder3 / 29757100
blood9 / 12347872
bone10 / 71655139
bone marrow2 / 4880140
brain121 / 1100989109
cervix16 / 48171332
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue39 / 215722180
esophagus1 / 2020949
eye40 / 211054189
heart4 / 8962644
intestine56 / 234472238
kidney17 / 21177780
larynx0 / 241450 
liver27 / 207743129
lung68 / 336974201
lymph6 / 44270135
lymph node28 / 91610305
mammary gland18 / 153271117
mouth5 / 6705274
muscle27 / 107715250
nerve1 / 1576863
ovary38 / 102051372
pancreas42 / 214812195
parathyroid4 / 20539194
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta52 / 280825185
prostate18 / 18934595
salivary gland18 / 20155893
skin83 / 210574394
spleen0 / 539520 
stomach17 / 96619175
testis44 / 330442133
thymus7 / 8113186
thyroid2 / 4747342
tonsil4 / 16999235
trachea1 / 5241319
umbilical cord1 / 1368073
uterus37 / 232878158
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201271_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts212.9
Adipocyte35.25
AdrenalCortex24.1
Adrenalgland19.95
Amygdala20.3
Appendix22.1
AtrioventricularNode17.3
BDCA4+_DentriticCells236.7
Bonemarrow29.6
BronchialEpithelialCells60.4
CD105+_Endothelial50.5
CD14+_Monocytes159.9
CD19+_BCells(neg._sel.)132.5
CD33+_Myeloid140.35
CD34+102.05
CD4+_Tcells71.6
CD56+_NKCells288.3
CD71+_EarlyErythroid53.1
CD8+_Tcells56.2
CardiacMyocytes91.35
Caudatenucleus21.1
Cerebellum22.8
CerebellumPeduncles37.3
CiliaryGanglion17.1
CingulateCortex24.4
Colorectaladenocarcinoma316.7
DorsalRootGanglion16.85
FetalThyroid88.55
Fetalbrain35.9
Fetalliver21
Fetallung56.55
GlobusPallidus15.6
Heart113.65
Hypothalamus32.95
Kidney21.55
Leukemia_chronicMyelogenousK-56257.3
Leukemia_promyelocytic-HL-6053.35
Leukemialymphoblastic(MOLT-4)375.9
Liver44.15
Lung241.5
Lymphnode39.5
Lymphoma_burkitts(Daudi)83.85
Lymphoma_burkitts(Raji)168.9
MedullaOblongata21.6
OccipitalLobe21.2
OlfactoryBulb25.25
Ovary19.1
Pancreas57.85
PancreaticIslet24.9
ParietalLobe22.05
Pituitary25.75
Placenta42.95
Pons23.35
PrefrontalCortex33.1
Prostate125.3
Salivarygland20.1
SkeletalMuscle30.55
Skin23.9
SmoothMuscle82.15
Spinalcord37.3
SubthalamicNucleus18.15
SuperiorCervicalGanglion23.3
TemporalLobe22.25
Testis82.25
TestisGermCell81.2
TestisIntersitial46.5
TestisLeydigCell43.75
TestisSeminiferousTubule75.5
Thalamus31.8
Thymus132.2
Thyroid209.05
Tongue19.55
Tonsil48.85
Trachea38.2
TrigeminalGanglion22.8
Uterus56.9
UterusCorpus28.9
WholeBlood144.9
Wholebrain40.55
colon54.9
pineal_day29.74
pineal_night26.06
retina34.325
small_intestine28.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1331_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.97 ± 0.67
Basal Forebrain3.9 ± 0.53
Basal Part of Pons4.39 ± 0.53
Cerebellar Cortex4.37 ± 0.6
Cerebellar Nuclei3.79 ± 0.52
Claustrum3.63 ± 0.88
Epithalamus4.23 ± 0.56
Frontal Lobe4.19 ± 0.64
Globus Pallidus3.99 ± 0.31
Hypothalamus3.76 ± 0.84
Insula3.93 ± 0.63
Limbic Lobe3.67 ± 0.72
Mesencephalon4.04 ± 0.76
Myelencephalon3.99 ± 0.63
Occipital Lobe3.73 ± 0.59
Parietal Lobe3.97 ± 0.65
Pontine Tegmentum3.96 ± 0.59
Striatum3.57 ± 0.5
Subthalamus3.89 ± 0.14
Temporal Lobe3.96 ± 0.6
Thalamus4.19 ± 0.59
White Matter4.82 ± 0.7
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
RalyCBCerebellum100
100
RalyCTXCerebral cortex100
100
RalyHIPHippocampal region93.19
100
RalyHPFHippocampal formation100
100
RalyHYHypothalamus73.14
76.2
RalyLSXLateral septal complex100
100
RalyMBMidbrain74.53
88.83
RalyMYMedulla65.03
100
RalyOLFOlfactory bulb100
100
RalyPPons64.67
95.4
RalyPALPallidum83.27
98.2
RalyRHPRetrohippocampal region100
100
RalysAMYStriatum-like amygdalar nuclei100
100
RalySTRStriatum100
100
RalySTRdStriatum dorsal region100
100
RalySTRvStriatum ventral region100
100
RalyTHThalamus99.77
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00079781 19 48 66 VAGCSVHKGYAFVQYSNER Peptide Atlas
RALY_HUMAN_2 21 2 22 SLKLQASNVTNKNDPKSINSR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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