AutismKB 2.0

Annotation Detail for RAB18


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Basic Information Top
Gene Symbol:RAB18 ( RAB18LI1 )
Gene Full Name: RAB18, member RAS oncogene family
Band: 10p12.1
Quick LinksEntrez ID:22931; OMIM: 602207; Uniprot ID:RAB18_HUMAN; ENSEMBL ID: ENSG00000099246; HGNC ID: 14244
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst8 / 62319128
fetus79 / 564012140
neonate9 / 31097289
infant1 / 2362042
juvenile8 / 55556143
adult220 / 1939121113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma5 / 17475286
breast (mammary gland) tumor4 / 9417842
cervical tumor1 / 3436629
chondrosarcoma6 / 8282372
colorectal tumor4 / 11424635
esophageal tumor7 / 17290404
gastrointestinal tumor11 / 11936992
germ cell tumor43 / 263845162
glioma10 / 10688393
head and neck tumor15 / 136302110
kidney tumor6 / 6895987
leukemia8 / 9584283
liver tumor11 / 96359114
lung tumor8 / 10312777
lymphoma1 / 7175513
non-neoplasia24 / 97250246
normal509 / 3360307151
ovarian tumor0 / 766820 
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer13 / 102680126
retinoblastoma4 / 4635686
skin tumor5 / 12494940
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland4 / 33197120
ascites7 / 40015174
bladder7 / 29757235
blood7 / 12347856
bone3 / 7165541
bone marrow5 / 48801102
brain326 / 1100989296
cervix2 / 4817141
connective tissue11 / 14925573
ear1 / 1621261
embryonic tissue29 / 215722134
esophagus7 / 20209346
eye24 / 211054113
heart8 / 8962689
intestine11 / 23447246
kidney25 / 211777118
larynx0 / 241450 
liver19 / 20774391
lung35 / 336974103
lymph0 / 442700 
lymph node16 / 91610174
mammary gland10 / 15327165
mouth15 / 67052223
muscle4 / 10771537
nerve1 / 1576863
ovary0 / 1020510 
pancreas31 / 214812144
parathyroid4 / 20539194
pharynx1 / 4132824
pituitary gland8 / 16585482
placenta39 / 280825138
prostate29 / 189345153
salivary gland0 / 201550 
skin21 / 21057499
spleen6 / 53952111
stomach5 / 9661951
testis52 / 330442157
thymus13 / 81131160
thyroid0 / 474730 
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord2 / 13680146
uterus39 / 232878167
vascular5 / 5178096
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P138376
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala11.64 ± 0.54
Basal Forebrain11.46 ± 0.63
Basal Part of Pons11.3 ± 0.56
Cerebellar Cortex10.92 ± 0.48
Cerebellar Nuclei11.6 ± 0.57
Claustrum12.09 ± 0.73
Epithalamus10.52 ± 0.61
Frontal Lobe11.36 ± 0.69
Globus Pallidus12.52 ± 0.42
Hypothalamus11.05 ± 0.58
Insula10.98 ± 0.62
Limbic Lobe11.6 ± 0.77
Mesencephalon11.59 ± 0.52
Myelencephalon11.54 ± 0.71
Occipital Lobe11.5 ± 0.81
Parietal Lobe11.46 ± 0.67
Pontine Tegmentum11.33 ± 0.73
Striatum11.41 ± 0.69
Subthalamus11.23 ± 0.31
Temporal Lobe11.34 ± 0.67
Thalamus11.41 ± 0.51
White Matter11.77 ± 0.75
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rab18CBCerebellum25.68
57.21
Rab18CTXCerebral cortex87.11
77.47
Rab18HIPHippocampal region47.2
81.45
Rab18HPFHippocampal formation45.24
59.85
Rab18HYHypothalamus22.03
19.49
Rab18LSXLateral septal complex13
9.93
Rab18MBMidbrain35.44
37.88
Rab18MYMedulla48.09
63.07
Rab18OLFOlfactory bulb48.29
42.65
Rab18PPons35.03
43.93
Rab18PALPallidum28.01
30.28
Rab18RHPRetrohippocampal region44.18
36.48
Rab18sAMYStriatum-like amygdalar nuclei29.34
21.97
Rab18STRStriatum22.85
17.94
Rab18STRdStriatum dorsal region24.36
19.62
Rab18STRvStriatum ventral region19.94
14.67
Rab18THThalamus47.8
53.06
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00003533 11 143 153 HSMLFIEASAK Peptide Atlas
RAB18_HUMAN_0 0 0 0 ILIIGESGVGK PRIDE
RAB18_HUMAN_10 11 10 20 ILIIGESGVGK PRIDE
RAB18_HUMAN_141 12 141 152 KHSMLFIEASAK PRIDE
RAB18_HUMAN_153 15 153 167 TCDGVQCAFEELVEK PRIDE
RAB18_HUMAN_168 15 168 182 IIQTPGLWESENQNK PRIDE
RAB18_HUMAN_58 11 58 68 LAIWDTAGQER PRIDE
RAB18_HUMAN_79 13 79 91 GAQGVILVYDVTR PRIDE
RAB18_HUMAN_98 14 98 111 LDNWLNELETYCTR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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