AutismKB 2.0

Annotation Detail for PTGR1


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Basic Information Top
Gene Symbol:PTGR1 ( FLJ99229,LTB4DH,MGC34943,PGR1,ZADH3 )
Gene Full Name: prostaglandin reductase 1
Band: 9q31.3
Quick LinksEntrez ID:22949; OMIM: 601274; Uniprot ID:PTGR1_HUMAN; ENSEMBL ID: ENSG00000106853; HGNC ID: 18429
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst6 / 6231996
fetus20 / 56401235
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult86 / 193912144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma4 / 10688337
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor21 / 96359217
lung tumor6 / 10312758
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal86 / 336030725
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer6 / 10268058
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor35 / 125191279
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain25 / 110098922
cervix1 / 4817120
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye4 / 21105418
heart6 / 8962666
intestine8 / 23447234
kidney16 / 21177775
larynx0 / 241450 
liver32 / 207743154
lung16 / 33697447
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth1 / 6705214
muscle3 / 10771527
nerve1 / 1576863
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta1 / 2808253
prostate10 / 18934552
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P157809
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.5 ± 0.34
Basal Forebrain7.37 ± 0.17
Basal Part of Pons7.83 ± 0.24
Cerebellar Cortex7.61 ± 0.24
Cerebellar Nuclei7.15 ± 0.4
Claustrum7.65 ± 0.8
Epithalamus7.84 ± 0.42
Frontal Lobe7.48 ± 0.39
Globus Pallidus7.17 ± 0.29
Hypothalamus7.4 ± 0.3
Insula7.51 ± 0.21
Limbic Lobe7.68 ± 0.43
Mesencephalon7.3 ± 0.35
Myelencephalon7.37 ± 0.43
Occipital Lobe7.5 ± 0.4
Parietal Lobe7.45 ± 0.34
Pontine Tegmentum7.41 ± 0.39
Striatum7.59 ± 0.37
Subthalamus7.39 ± 0.25
Temporal Lobe7.41 ± 0.34
Thalamus7.09 ± 0.29
White Matter5.87 ± 0.67
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ltb4dhCBCerebellum7.33
8.74
Ltb4dhCTXCerebral cortex11.42
8.6
Ltb4dhHIPHippocampal region7.03
6.48
Ltb4dhHPFHippocampal formation6.59
5.51
Ltb4dhHYHypothalamus3.42
3.07
Ltb4dhLSXLateral septal complex4.92
5.6
Ltb4dhMBMidbrain2.9
3.54
Ltb4dhMYMedulla13.45
13.69
Ltb4dhOLFOlfactory bulb29.08
25.22
Ltb4dhPPons7.99
7.66
Ltb4dhPALPallidum5.15
4.27
Ltb4dhRHPRetrohippocampal region5.88
4.16
Ltb4dhsAMYStriatum-like amygdalar nuclei1.46
1.52
Ltb4dhSTRStriatum5.31
4.12
Ltb4dhSTRdStriatum dorsal region1.09
0.93
Ltb4dhSTRvStriatum ventral region21.87
14.43
Ltb4dhTHThalamus1.75
1.53
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000704 26 206 231 ASPDGYDCYFDNVGGEFSNTVIGQMK Peptide Atlas
PTGR1_HUMAN_184 10 184 193 LGFDVVFNYK PRIDE
PTGR1_HUMAN_247 19 247 265 TGPLPPGPPPEIVIYQELR PRIDE
PTGR1_HUMAN_266 8 266 273 MEAFVVYR PRIDE
PTGR1_HUMAN_59 12 59 70 EGDTMMGQQVAK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018