AutismKB 2.0

Annotation Detail for MAST1


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Basic Information Top
Gene Symbol:MAST1 ( KIAA0973,SAST,SAST170 )
Gene Full Name: microtubule associated serine/threonine kinase 1
Band: 19p13.2
Quick LinksEntrez ID:22983; OMIM: 612256; Uniprot ID:MAST1_HUMAN; ENSEMBL ID: ENSG00000105613; HGNC ID: 19034
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst3 / 6231948
fetus15 / 56401226
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult37 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma6 / 10688356
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia5 / 9584252
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal54 / 336030716
ovarian tumor4 / 7668252
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood5 / 12347840
bone1 / 7165513
bone marrow0 / 488010 
brain42 / 110098938
cervix2 / 4817141
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye17 / 21105480
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve2 / 15768126
ovary4 / 10205139
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta3 / 28082510
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217231_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.5
Adipocyte3.55
AdrenalCortex3.75
Adrenalgland3
Amygdala3.8
Appendix3.55
AtrioventricularNode2.7
BDCA4+_DentriticCells3.9
Bonemarrow3.5
BronchialEpithelialCells3.55
CD105+_Endothelial3.55
CD14+_Monocytes3.8
CD19+_BCells(neg._sel.)3.75
CD33+_Myeloid4.5
CD34+4.55
CD4+_Tcells3.85
CD56+_NKCells4.25
CD71+_EarlyErythroid3.35
CD8+_Tcells3.4
CardiacMyocytes4.45
Caudatenucleus3.2
Cerebellum2.9
CerebellumPeduncles7.5
CiliaryGanglion2.5
CingulateCortex6.7
Colorectaladenocarcinoma3.55
DorsalRootGanglion2.75
FetalThyroid3.45
Fetalbrain39.85
Fetalliver3.1
Fetallung2.95
GlobusPallidus5.95
Heart4.5
Hypothalamus4.1
Kidney2.9
Leukemia_chronicMyelogenousK-5623.25
Leukemia_promyelocytic-HL-603.2
Leukemialymphoblastic(MOLT-4)2.9
Liver4.7
Lung3.9
Lymphnode3.05
Lymphoma_burkitts(Daudi)4.6
Lymphoma_burkitts(Raji)5
MedullaOblongata3.4
OccipitalLobe3.2
OlfactoryBulb2.85
Ovary2.35
Pancreas2.9
PancreaticIslet3.8
ParietalLobe3.85
Pituitary4.2
Placenta3.7
Pons3.4
PrefrontalCortex6.75
Prostate4.15
Salivarygland2.85
SkeletalMuscle4.25
Skin2.75
SmoothMuscle4.05
Spinalcord3.8
SubthalamicNucleus6.15
SuperiorCervicalGanglion4.05
TemporalLobe3.3
Testis3.05
TestisGermCell2.95
TestisIntersitial3
TestisLeydigCell3.55
TestisSeminiferousTubule3.1
Thalamus7.2
Thymus2.8
Thyroid4.5
Tongue3.5
Tonsil3.5
Trachea3
TrigeminalGanglion3.55
Uterus2.9
UterusCorpus3.2
WholeBlood3.9
Wholebrain3.4
colon3.55
pineal_day4.52
pineal_night4.4
retina4.275
small_intestine3.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8180_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.97 ± 0.96
Basal Forebrain2.65 ± 0.71
Basal Part of Pons2.46 ± 0.6
Cerebellar Cortex2.88 ± 0.78
Cerebellar Nuclei3.01 ± 0.63
Claustrum3.48 ± 0.94
Epithalamus2.08 ± 0.78
Frontal Lobe2.69 ± 0.77
Globus Pallidus2.44 ± 0.59
Hypothalamus2.44 ± 0.78
Insula2.5 ± 0.82
Limbic Lobe2.81 ± 0.68
Mesencephalon2.82 ± 0.82
Myelencephalon2.67 ± 0.73
Occipital Lobe2.58 ± 0.76
Parietal Lobe2.57 ± 0.77
Pontine Tegmentum2.58 ± 0.7
Striatum2.15 ± 0.77
Subthalamus2.57 ± 0.64
Temporal Lobe2.7 ± 0.73
Thalamus2.53 ± 0.85
White Matter2.09 ± 0.2
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mast1CBCerebellum100
100
Mast1CTXCerebral cortex100
100
Mast1HIPHippocampal region65.85
100
Mast1HPFHippocampal formation98.64
100
Mast1HYHypothalamus100
100
Mast1LSXLateral septal complex49.71
47.84
Mast1MBMidbrain100
100
Mast1MYMedulla93.37
100
Mast1OLFOlfactory bulb100
100
Mast1PPons100
100
Mast1PALPallidum88.2
100
Mast1RHPRetrohippocampal region100
100
Mast1sAMYStriatum-like amygdalar nuclei100
100
Mast1STRStriatum38.22
36.26
Mast1STRdStriatum dorsal region26.92
25.65
Mast1STRvStriatum ventral region27.81
24.43
Mast1THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MAST1_HUMAN_248 15 248 262 LQENLEKLLQDAYER PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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