AutismKB 2.0

Annotation Detail for PDCD11


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Basic Information Top
Gene Symbol:PDCD11 ( ALG-4,ALG4,KIAA0185,NFBP,RRP5 )
Gene Full Name: programmed cell death 11
Band: 10q24.33
Quick LinksEntrez ID:22984; OMIM: 612333; Uniprot ID:RRP5_HUMAN; ENSEMBL ID: ENSG00000148843; HGNC ID: 13408
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst7 / 62319112
fetus26 / 56401246
neonate0 / 310970 
infant1 / 2362042
juvenile2 / 5555635
adult85 / 193912143
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor7 / 9417874
cervical tumor0 / 343660 
chondrosarcoma7 / 8282384
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor9 / 11936975
germ cell tumor27 / 263845102
glioma6 / 10688356
head and neck tumor3 / 13630222
kidney tumor3 / 6895943
leukemia9 / 9584293
liver tumor10 / 96359103
lung tumor4 / 10312738
lymphoma23 / 71755320
non-neoplasia4 / 9725041
normal132 / 336030739
ovarian tumor2 / 7668226
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer3 / 10268029
retinoblastoma10 / 46356215
skin tumor12 / 12494996
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites4 / 4001599
bladder1 / 2975733
blood10 / 12347880
bone4 / 7165555
bone marrow0 / 488010 
brain29 / 110098926
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue14 / 21572264
esophagus0 / 202090 
eye17 / 21105480
heart3 / 8962633
intestine24 / 234472102
kidney10 / 21177747
larynx1 / 2414541
liver16 / 20774377
lung15 / 33697444
lymph22 / 44270496
lymph node20 / 91610218
mammary gland8 / 15327152
mouth0 / 670520 
muscle5 / 10771546
nerve1 / 1576863
ovary5 / 10205148
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta8 / 28082528
prostate3 / 18934515
salivary gland0 / 201550 
skin19 / 21057490
spleen0 / 539520 
stomach3 / 9661931
testis7 / 33044221
thymus0 / 811310 
thyroid3 / 4747363
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus13 / 23287855
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212422_at
Cell line Expression level Expression bar
721_B_lymphoblasts177.1
Adipocyte27.9
AdrenalCortex31.55
Adrenalgland23.3
Amygdala27.8
Appendix26.8
AtrioventricularNode20.55
BDCA4+_DentriticCells30.15
Bonemarrow28.9
BronchialEpithelialCells40.7
CD105+_Endothelial27.55
CD14+_Monocytes27.25
CD19+_BCells(neg._sel.)26.7
CD33+_Myeloid32.5
CD34+53.1
CD4+_Tcells30.3
CD56+_NKCells30.55
CD71+_EarlyErythroid26.45
CD8+_Tcells49.35
CardiacMyocytes39.45
Caudatenucleus24.5
Cerebellum22.8
CerebellumPeduncles31.15
CiliaryGanglion21.3
CingulateCortex29.05
Colorectaladenocarcinoma30.2
DorsalRootGanglion22
FetalThyroid27.1
Fetalbrain26.75
Fetalliver24.85
Fetallung21.95
GlobusPallidus20.3
Heart36.9
Hypothalamus29.45
Kidney23.95
Leukemia_chronicMyelogenousK-56233.85
Leukemia_promyelocytic-HL-6045
Leukemialymphoblastic(MOLT-4)25.9
Liver36.95
Lung29.85
Lymphnode24
Lymphoma_burkitts(Daudi)66.2
Lymphoma_burkitts(Raji)57.75
MedullaOblongata26.9
OccipitalLobe27.35
OlfactoryBulb19.85
Ovary19.35
Pancreas24.35
PancreaticIslet29
ParietalLobe30.5
Pituitary30.35
Placenta27.1
Pons27.05
PrefrontalCortex36.25
Prostate28.65
Salivarygland21.3
SkeletalMuscle39.9
Skin20.9
SmoothMuscle31.25
Spinalcord28.7
SubthalamicNucleus24.75
SuperiorCervicalGanglion30.8
TemporalLobe25.95
Testis53.3
TestisGermCell30.5
TestisIntersitial78.85
TestisLeydigCell73.65
TestisSeminiferousTubule52.1
Thalamus26.75
Thymus23.25
Thyroid33.15
Tongue28.9
Tonsil28
Trachea22.8
TrigeminalGanglion30.15
Uterus21.65
UterusCorpus26.5
WholeBlood28.8
Wholebrain22.4
colon28.15
pineal_day33.62
pineal_night33
retina33.75
small_intestine26.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7609_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.78 ± 0.36
Basal Forebrain5.84 ± 0.21
Basal Part of Pons6.08 ± 0.17
Cerebellar Cortex6.22 ± 0.22
Cerebellar Nuclei5.81 ± 0.27
Claustrum5.71 ± 0.41
Epithalamus6.08 ± 0.43
Frontal Lobe5.84 ± 0.36
Globus Pallidus6 ± 0.38
Hypothalamus5.83 ± 0.35
Insula5.85 ± 0.23
Limbic Lobe5.99 ± 0.36
Mesencephalon5.93 ± 0.38
Myelencephalon5.92 ± 0.38
Occipital Lobe6.19 ± 0.34
Parietal Lobe5.95 ± 0.28
Pontine Tegmentum5.91 ± 0.4
Striatum6.23 ± 0.39
Subthalamus5.33 ± 0.37
Temporal Lobe5.9 ± 0.3
Thalamus5.98 ± 0.34
White Matter6.18 ± 0.2
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000524 16 1751 1766 ALECLPSKEHVDVIAK Peptide Atlas
RRP5_HUMAN_2 9 2 10 ANLEESFPR PRIDE
RRP5_HUMAN_539 13 539 551 AKPGLQTHGFIIR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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