AutismKB 2.0

Annotation Detail for PCNX


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Basic Information Top
Gene Symbol:PCNX ( FLJ23409,FLJ45663,KIAA0805,KIAA0995,PCNXL1 )
Gene Full Name: pecanex homolog (Drosophila)
Band: 14q24.2
Quick LinksEntrez ID:22990; OMIM: NA; Uniprot ID:PCX1_HUMAN; ENSEMBL ID: ENSG00000100731; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst4 / 6231964
fetus33 / 56401258
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult97 / 193912150
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma9 / 82823108
colorectal tumor6 / 11424652
esophageal tumor1 / 1729057
gastrointestinal tumor5 / 11936941
germ cell tumor5 / 26384518
glioma1 / 1068839
head and neck tumor6 / 13630244
kidney tumor4 / 6895958
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor5 / 10312748
lymphoma2 / 7175527
non-neoplasia6 / 9725061
normal165 / 336030749
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer4 / 10268038
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood7 / 12347856
bone8 / 71655111
bone marrow1 / 4880120
brain38 / 110098934
cervix4 / 4817183
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus1 / 2020949
eye6 / 21105428
heart0 / 896260 
intestine10 / 23447242
kidney12 / 21177756
larynx1 / 2414541
liver3 / 20774314
lung23 / 33697468
lymph2 / 4427045
lymph node4 / 9161043
mammary gland3 / 15327119
mouth4 / 6705259
muscle11 / 107715102
nerve1 / 1576863
ovary0 / 1020510 
pancreas20 / 21481293
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta8 / 28082528
prostate6 / 18934531
salivary gland0 / 201550 
skin7 / 21057433
spleen1 / 5395218
stomach3 / 9661931
testis13 / 33044239
thymus5 / 8113161
thyroid2 / 4747342
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus12 / 23287851
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213173_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.85
Adipocyte9.5
AdrenalCortex14.1
Adrenalgland8.3
Amygdala10
Appendix12.05
AtrioventricularNode9.45
BDCA4+_DentriticCells10.75
Bonemarrow11.6
BronchialEpithelialCells8.55
CD105+_Endothelial9.9
CD14+_Monocytes11.15
CD19+_BCells(neg._sel.)11.8
CD33+_Myeloid41.45
CD34+11.6
CD4+_Tcells10.9
CD56+_NKCells11.3
CD71+_EarlyErythroid9.15
CD8+_Tcells9.65
CardiacMyocytes17
Caudatenucleus8.25
Cerebellum7.85
CerebellumPeduncles11.6
CiliaryGanglion8.25
CingulateCortex9.75
Colorectaladenocarcinoma8.7
DorsalRootGanglion8.3
FetalThyroid9.5
Fetalbrain9.15
Fetalliver8.4
Fetallung7.15
GlobusPallidus7.5
Heart15.3
Hypothalamus10.4
Kidney8.3
Leukemia_chronicMyelogenousK-5628.65
Leukemia_promyelocytic-HL-608.25
Leukemialymphoblastic(MOLT-4)7.35
Liver13.55
Lung9.95
Lymphnode8.3
Lymphoma_burkitts(Daudi)12.9
Lymphoma_burkitts(Raji)14.35
MedullaOblongata8.35
OccipitalLobe8.75
OlfactoryBulb7.6
Ovary7.3
Pancreas8.05
PancreaticIslet9.8
ParietalLobe10.95
Pituitary10.75
Placenta9.4
Pons10.2
PrefrontalCortex11.75
Prostate10.4
Salivarygland8
SkeletalMuscle13.65
Skin8.85
SmoothMuscle11.05
Spinalcord10.35
SubthalamicNucleus9.05
SuperiorCervicalGanglion13.95
TemporalLobe9.4
Testis7.9
TestisGermCell7.55
TestisIntersitial8.05
TestisLeydigCell10.85
TestisSeminiferousTubule8.35
Thalamus9.85
Thymus6.15
Thyroid11
Tongue10.6
Tonsil9.4
Trachea7.9
TrigeminalGanglion12.15
Uterus7.55
UterusCorpus9.95
WholeBlood10.7
Wholebrain7.4
colon9.8
pineal_day12.26
pineal_night11.94
retina11.675
small_intestine9.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13844_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.83 ± 0.27
Basal Forebrain6.56 ± 0.26
Basal Part of Pons6.52 ± 0.34
Cerebellar Cortex6.5 ± 0.2
Cerebellar Nuclei6.22 ± 0.3
Claustrum6.34 ± 0.56
Epithalamus6.47 ± 0.32
Frontal Lobe6.62 ± 0.32
Globus Pallidus6.22 ± 0.26
Hypothalamus6.57 ± 0.31
Insula6.63 ± 0.23
Limbic Lobe6.82 ± 0.32
Mesencephalon6.64 ± 0.33
Myelencephalon6.59 ± 0.35
Occipital Lobe6.68 ± 0.33
Parietal Lobe6.62 ± 0.3
Pontine Tegmentum6.66 ± 0.39
Striatum7.11 ± 0.29
Subthalamus6.63 ± 0.08
Temporal Lobe6.7 ± 0.29
Thalamus6.44 ± 0.33
White Matter6.84 ± 0.38
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
PcnxCBCerebellum18.52
21.4
PcnxCTXCerebral cortex89.99
79.44
PcnxHIPHippocampal region81.22
100
PcnxHPFHippocampal formation75.63
100
PcnxHYHypothalamus40.81
35.04
PcnxLSXLateral septal complex27.47
22.77
PcnxMBMidbrain19.46
18.24
PcnxMYMedulla25.51
28.49
PcnxOLFOlfactory bulb51.07
45.06
PcnxPPons21.87
22.99
PcnxPALPallidum24.89
23.47
PcnxRHPRetrohippocampal region63.9
59.48
PcnxsAMYStriatum-like amygdalar nuclei45.19
39.76
PcnxSTRStriatum36.9
29.98
PcnxSTRdStriatum dorsal region31.06
24.75
PcnxSTRvStriatum ventral region52.61
39.75
PcnxTHThalamus37.11
34.41
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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