AutismKB 2.0

Annotation Detail for KDM2A


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Basic Information Top
Gene Symbol:KDM2A ( CXXC8,DKFZp434M1735,FBL11,FBL7,FBXL11,FLJ00115,FLJ46431,JHDM1A,KIAA1004,LILINA,SF-KDM2A )
Gene Full Name: lysine (K)-specific demethylase 2A
Band: 11q13.2
Quick LinksEntrez ID:22992; OMIM: 605657; Uniprot ID:KDM2A_HUMAN; ENSEMBL ID: ENSG00000173120; HGNC ID: 13606
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst6 / 6231996
fetus62 / 564012109
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult205 / 1939121105
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor4 / 12794312
bladder carcinoma7 / 17475400
breast (mammary gland) tumor8 / 9417884
cervical tumor1 / 3436629
chondrosarcoma13 / 82823156
colorectal tumor8 / 11424670
esophageal tumor3 / 17290173
gastrointestinal tumor10 / 11936983
germ cell tumor21 / 26384579
glioma7 / 10688365
head and neck tumor19 / 136302139
kidney tumor2 / 6895929
leukemia26 / 95842271
liver tumor4 / 9635941
lung tumor5 / 10312748
lymphoma5 / 7175569
non-neoplasia13 / 97250133
normal247 / 336030773
ovarian tumor7 / 7668291
pancreatic tumor11 / 104616105
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer4 / 10268038
retinoblastoma5 / 46356107
skin tumor2 / 12494916
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor14 / 90257155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites6 / 40015149
bladder3 / 29757100
blood26 / 123478210
bone10 / 71655139
bone marrow0 / 488010 
brain40 / 110098936
cervix1 / 4817120
connective tissue10 / 14925566
ear0 / 162120 
embryonic tissue24 / 215722111
esophagus3 / 20209148
eye33 / 211054156
heart8 / 8962689
intestine12 / 23447251
kidney10 / 21177747
larynx7 / 24145289
liver11 / 20774352
lung22 / 33697465
lymph3 / 4427067
lymph node20 / 91610218
mammary gland13 / 15327184
mouth6 / 6705289
muscle3 / 10771527
nerve3 / 15768190
ovary7 / 10205168
pancreas19 / 21481288
parathyroid3 / 20539146
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta16 / 28082556
prostate6 / 18934531
salivary gland1 / 2015549
skin10 / 21057447
spleen3 / 5395255
stomach4 / 9661941
testis18 / 33044254
thymus3 / 8113136
thyroid9 / 47473189
tonsil2 / 16999117
trachea0 / 524130 
umbilical cord2 / 13680146
uterus31 / 232878133
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208989_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts40.55
Adipocyte32.2
AdrenalCortex35.8
Adrenalgland27.15
Amygdala29.4
Appendix32.65
AtrioventricularNode31.15
BDCA4+_DentriticCells58
Bonemarrow31.95
BronchialEpithelialCells29.75
CD105+_Endothelial30.85
CD14+_Monocytes53.05
CD19+_BCells(neg._sel.)70.5
CD33+_Myeloid78.85
CD34+43.95
CD4+_Tcells113.45
CD56+_NKCells61.2
CD71+_EarlyErythroid31.75
CD8+_Tcells80.2
CardiacMyocytes40
Caudatenucleus29.45
Cerebellum26.3
CerebellumPeduncles42.2
CiliaryGanglion24.35
CingulateCortex33.75
Colorectaladenocarcinoma32.4
DorsalRootGanglion31.75
FetalThyroid40.25
Fetalbrain33.15
Fetalliver26.05
Fetallung27.55
GlobusPallidus24.2
Heart40.6
Hypothalamus35.75
Kidney26.65
Leukemia_chronicMyelogenousK-56230
Leukemia_promyelocytic-HL-6028.4
Leukemialymphoblastic(MOLT-4)26.35
Liver34.75
Lung33.1
Lymphnode29.05
Lymphoma_burkitts(Daudi)42.75
Lymphoma_burkitts(Raji)32.85
MedullaOblongata29.6
OccipitalLobe29.4
OlfactoryBulb25.8
Ovary22
Pancreas25.95
PancreaticIslet34.7
ParietalLobe39.55
Pituitary34.4
Placenta34.35
Pons34.6
PrefrontalCortex41.5
Prostate37.25
Salivarygland26.2
SkeletalMuscle38.1
Skin32.95
SmoothMuscle36.25
Spinalcord34.85
SubthalamicNucleus29.95
SuperiorCervicalGanglion36.65
TemporalLobe34.75
Testis27.85
TestisGermCell33.85
TestisIntersitial44.15
TestisLeydigCell35.65
TestisSeminiferousTubule34.4
Thalamus33.3
Thymus25.5
Thyroid34.45
Tongue41.2
Tonsil31.8
Trachea25.6
TrigeminalGanglion43.65
Uterus25.95
UterusCorpus29
WholeBlood43.55
Wholebrain27.7
colon23.35
pineal_day45.38
pineal_night42.86
retina39.875
small_intestine29.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14134_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.97 ± 0.42
Basal Forebrain6.55 ± 0.4
Basal Part of Pons6.61 ± 0.47
Cerebellar Cortex6.22 ± 0.42
Cerebellar Nuclei6.4 ± 0.4
Claustrum7.12 ± 0.62
Epithalamus5.98 ± 0.35
Frontal Lobe6.33 ± 0.53
Globus Pallidus7.07 ± 0.23
Hypothalamus6.24 ± 0.29
Insula6.43 ± 0.43
Limbic Lobe6.93 ± 0.53
Mesencephalon6.54 ± 0.44
Myelencephalon6.59 ± 0.57
Occipital Lobe7.03 ± 0.53
Parietal Lobe6.58 ± 0.54
Pontine Tegmentum6.38 ± 0.56
Striatum6.83 ± 0.52
Subthalamus6.47 ± 0.42
Temporal Lobe6.43 ± 0.59
Thalamus6.4 ± 0.42
White Matter7.12 ± 0.56
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fbxl11CBCerebellum40.2
52.74
Fbxl11CTXCerebral cortex90.03
75.95
Fbxl11HIPHippocampal region64.62
100
Fbxl11HPFHippocampal formation68.34
92.11
Fbxl11HYHypothalamus47.7
37.65
Fbxl11LSXLateral septal complex51.67
39.17
Fbxl11MBMidbrain44.45
41.01
Fbxl11MYMedulla38.54
41.45
Fbxl11OLFOlfactory bulb65.4
60.01
Fbxl11PPons39.91
40.82
Fbxl11PALPallidum43.24
38.35
Fbxl11RHPRetrohippocampal region75.76
66.73
Fbxl11sAMYStriatum-like amygdalar nuclei67.05
50.78
Fbxl11STRStriatum62.89
47.78
Fbxl11STRdStriatum dorsal region68.43
52.59
Fbxl11STRvStriatum ventral region47.31
34.95
Fbxl11THThalamus47.43
40.82
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00001191 14 463 476 CLVDKLESLPLHKK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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