AutismKB 2.0

Annotation Detail for DAAM1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:DAAM1 ( FLJ41657,KIAA0666 )
Gene Full Name: dishevelled associated activator of morphogenesis 1
Band: 14q23.1
Quick LinksEntrez ID:23002; OMIM: 606626; Uniprot ID:DAAM1_HUMAN; ENSEMBL ID: ENSG00000100592; HGNC ID: 18142
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst0 / 623190 
fetus41 / 56401272
neonate1 / 3109732
infant0 / 236200 
juvenile1 / 5555617
adult59 / 193912130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor4 / 26384515
glioma1 / 1068839
head and neck tumor4 / 13630229
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia3 / 9725030
normal144 / 336030742
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer8 / 10268077
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites1 / 4001524
bladder0 / 297570 
blood6 / 12347848
bone1 / 7165513
bone marrow0 / 488010 
brain40 / 110098936
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye13 / 21105461
heart2 / 8962622
intestine5 / 23447221
kidney10 / 21177747
larynx1 / 2414541
liver4 / 20774319
lung11 / 33697432
lymph0 / 442700 
lymph node15 / 91610163
mammary gland3 / 15327119
mouth3 / 6705244
muscle4 / 10771537
nerve0 / 157680 
ovary2 / 10205119
pancreas3 / 21481213
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta9 / 28082532
prostate12 / 18934563
salivary gland0 / 201550 
skin6 / 21057428
spleen3 / 5395255
stomach4 / 9661941
testis10 / 33044230
thymus4 / 8113149
thyroid2 / 4747342
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord1 / 1368073
uterus4 / 23287817
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 216060_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts34.65
Adipocyte9.7
AdrenalCortex10.95
Adrenalgland8.75
Amygdala74.85
Appendix12.65
AtrioventricularNode10
BDCA4+_DentriticCells44.6
Bonemarrow10.15
BronchialEpithelialCells34.6
CD105+_Endothelial62.4
CD14+_Monocytes10.45
CD19+_BCells(neg._sel.)19.1
CD33+_Myeloid11.6
CD34+61.2
CD4+_Tcells8.8
CD56+_NKCells12.65
CD71+_EarlyErythroid167.1
CD8+_Tcells8.3
CardiacMyocytes85.8
Caudatenucleus8.8
Cerebellum8.5
CerebellumPeduncles12.5
CiliaryGanglion7.95
CingulateCortex15.5
Colorectaladenocarcinoma8.6
DorsalRootGanglion8.1
FetalThyroid12.6
Fetalbrain286.9
Fetalliver36.4
Fetallung16.95
GlobusPallidus9.15
Heart13.6
Hypothalamus12.35
Kidney8.35
Leukemia_chronicMyelogenousK-5628.95
Leukemia_promyelocytic-HL-608.95
Leukemialymphoblastic(MOLT-4)7.35
Liver13.1
Lung9.6
Lymphnode8
Lymphoma_burkitts(Daudi)26.85
Lymphoma_burkitts(Raji)14.2
MedullaOblongata8.95
OccipitalLobe26.25
OlfactoryBulb10.95
Ovary7.25
Pancreas8.15
PancreaticIslet19.9
ParietalLobe11.95
Pituitary14.65
Placenta9.45
Pons9.9
PrefrontalCortex78.6
Prostate11.75
Salivarygland10.05
SkeletalMuscle12.3
Skin25.3
SmoothMuscle117.2
Spinalcord10.65
SubthalamicNucleus9.65
SuperiorCervicalGanglion13.9
TemporalLobe9.85
Testis7.3
TestisGermCell21.8
TestisIntersitial9.3
TestisLeydigCell10.7
TestisSeminiferousTubule8.7
Thalamus10.65
Thymus7.1
Thyroid17.2
Tongue12.4
Tonsil38.35
Trachea15.4
TrigeminalGanglion11.45
Uterus80.2
UterusCorpus9.2
WholeBlood10.85
Wholebrain9.95
colon19.35
pineal_day20.12
pineal_night26.72
retina38.3
small_intestine9.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P54116
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.42 ± 0.61
Basal Forebrain7.05 ± 0.24
Basal Part of Pons7.12 ± 0.33
Cerebellar Cortex7.54 ± 0.14
Cerebellar Nuclei7.2 ± 0.51
Claustrum7.25 ± 0.4
Epithalamus7.95 ± 0.44
Frontal Lobe7.31 ± 0.31
Globus Pallidus6.78 ± 0.21
Hypothalamus7.71 ± 0.32
Insula7.38 ± 0.26
Limbic Lobe7.49 ± 0.36
Mesencephalon7.26 ± 0.49
Myelencephalon7.24 ± 0.45
Occipital Lobe7.54 ± 0.37
Parietal Lobe7.31 ± 0.41
Pontine Tegmentum7.29 ± 0.48
Striatum6.47 ± 0.49
Subthalamus7.67 ± 0.27
Temporal Lobe7.36 ± 0.27
Thalamus7.06 ± 0.28
White Matter5.77 ± 0.31
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Daam1CBCerebellum32.33
31.87
Daam1CTXCerebral cortex81.28
34.3
Daam1HIPHippocampal region56.36
42.85
Daam1HPFHippocampal formation58.39
35.17
Daam1HYHypothalamus100
48.42
Daam1LSXLateral septal complex46.2
14.24
Daam1MBMidbrain59.31
27.62
Daam1MYMedulla72.11
41.72
Daam1OLFOlfactory bulb79.8
40.64
Daam1PPons69.72
38.47
Daam1PALPallidum92.67
48.41
Daam1RHPRetrohippocampal region61.08
25.11
Daam1sAMYStriatum-like amygdalar nuclei94.62
35.61
Daam1STRStriatum46.86
18.52
Daam1STRdStriatum dorsal region38.42
15.51
Daam1STRvStriatum ventral region56.52
22.85
Daam1THThalamus80.21
37.21
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
DAAM1_HUMAN_142 24 142 165 TKPMRFVTRFIDLDGLSCILNFLK PRIDE
DAAM1_HUMAN_331 9 331 339 HLDFFEMLR PRIDE
PAp00000417 23 196 218 AHVLAHSESINVIAQSLSTENIK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved