AutismKB 2.0

Annotation Detail for MAPKBP1


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Basic Information Top
Gene Symbol:MAPKBP1 ( MGC138851,MGC138852 )
Gene Full Name: mitogen-activated protein kinase binding protein 1
Band: 15q15.1
Quick LinksEntrez ID:23005; OMIM: NA; Uniprot ID:MABP1_HUMAN; ENSEMBL ID: ENSG00000137802; HGNC ID: 29536
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus13 / 56401223
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult63 / 193912132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma3 / 17475171
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma5 / 10688346
head and neck tumor6 / 13630244
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor4 / 10312738
lymphoma1 / 7175513
non-neoplasia3 / 9725030
normal96 / 336030728
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder3 / 29757100
blood2 / 12347816
bone4 / 7165555
bone marrow0 / 488010 
brain46 / 110098941
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye5 / 21105423
heart1 / 8962611
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver1 / 2077434
lung8 / 33697423
lymph1 / 4427022
lymph node2 / 9161021
mammary gland0 / 1532710 
mouth2 / 6705229
muscle3 / 10771527
nerve0 / 157680 
ovary0 / 1020510 
pancreas8 / 21481237
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta10 / 28082535
prostate0 / 1893450 
salivary gland0 / 201550 
skin7 / 21057433
spleen0 / 539520 
stomach1 / 9661910
testis33 / 33044299
thymus3 / 8113136
thyroid4 / 4747384
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus10 / 23287842
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213394_at
Cell line Expression level Expression bar
721_B_lymphoblasts24.35
Adipocyte21.55
AdrenalCortex27.6
Adrenalgland20.05
Amygdala36.75
Appendix22.55
AtrioventricularNode16.8
BDCA4+_DentriticCells21.3
Bonemarrow24.85
BronchialEpithelialCells22.25
CD105+_Endothelial21.15
CD14+_Monocytes22.3
CD19+_BCells(neg._sel.)21.7
CD33+_Myeloid26.75
CD34+31.45
CD4+_Tcells22.85
CD56+_NKCells29
CD71+_EarlyErythroid10.15
CD8+_Tcells21.85
CardiacMyocytes26.8
Caudatenucleus25.6
Cerebellum43.9
CerebellumPeduncles78.75
CiliaryGanglion15.85
CingulateCortex27.55
Colorectaladenocarcinoma22.15
DorsalRootGanglion16.95
FetalThyroid25.9
Fetalbrain94.45
Fetalliver19.15
Fetallung18.7
GlobusPallidus19.05
Heart30
Hypothalamus24.6
Kidney18.05
Leukemia_chronicMyelogenousK-56220.35
Leukemia_promyelocytic-HL-6019.35
Leukemialymphoblastic(MOLT-4)18.7
Liver29.35
Lung25.1
Lymphnode17.85
Lymphoma_burkitts(Daudi)27.75
Lymphoma_burkitts(Raji)38.95
MedullaOblongata28
OccipitalLobe31.9
OlfactoryBulb28
Ovary14.7
Pancreas19
PancreaticIslet23.3
ParietalLobe30.25
Pituitary26.6
Placenta22.75
Pons27.85
PrefrontalCortex36.65
Prostate27.65
Salivarygland17.45
SkeletalMuscle29.35
Skin16.9
SmoothMuscle24.85
Spinalcord24.15
SubthalamicNucleus20.75
SuperiorCervicalGanglion25.2
TemporalLobe32.35
Testis38.8
TestisGermCell27.65
TestisIntersitial25.05
TestisLeydigCell23.5
TestisSeminiferousTubule42.5
Thalamus22.5
Thymus18
Thyroid56.5
Tongue22
Tonsil23.25
Trachea19.4
TrigeminalGanglion22.15
Uterus19.15
UterusCorpus26.7
WholeBlood23.2
Wholebrain37.05
colon21.6
pineal_day26.24
pineal_night25.92
retina25.55
small_intestine21.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P352226
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.81 ± 0.5
Basal Forebrain7.52 ± 0.18
Basal Part of Pons7.11 ± 0.34
Cerebellar Cortex7.7 ± 0.35
Cerebellar Nuclei7.07 ± 0.36
Claustrum8.09 ± 0.55
Epithalamus6.89 ± 0.59
Frontal Lobe7.04 ± 0.53
Globus Pallidus6.82 ± 0.39
Hypothalamus6.92 ± 0.56
Insula7.15 ± 0.55
Limbic Lobe7.45 ± 0.45
Mesencephalon7.08 ± 0.55
Myelencephalon7.26 ± 0.53
Occipital Lobe7.58 ± 0.43
Parietal Lobe7.23 ± 0.55
Pontine Tegmentum7.17 ± 0.51
Striatum7.11 ± 0.47
Subthalamus6.89 ± 0.26
Temporal Lobe7.19 ± 0.48
Thalamus6.97 ± 0.49
White Matter7.37 ± 0.36
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mapkbp1CBCerebellum25.37
32.95
Mapkbp1CTXCerebral cortex21.68
15.52
Mapkbp1HIPHippocampal region16.83
18.76
Mapkbp1HPFHippocampal formation14.95
14.54
Mapkbp1HYHypothalamus10.37
6.96
Mapkbp1LSXLateral septal complex22.53
14.04
Mapkbp1MBMidbrain13.76
11.3
Mapkbp1MYMedulla19.35
17.04
Mapkbp1OLFOlfactory bulb32.58
26.96
Mapkbp1PPons14.75
12.54
Mapkbp1PALPallidum9.85
7.09
Mapkbp1RHPRetrohippocampal region11.61
8.33
Mapkbp1sAMYStriatum-like amygdalar nuclei12.09
7.49
Mapkbp1STRStriatum16.92
11.53
Mapkbp1STRdStriatum dorsal region14.55
10.38
Mapkbp1STRvStriatum ventral region27.47
17.43
Mapkbp1THThalamus14.89
10.8
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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