AutismKB 2.0

Annotation Detail for FAIM2


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Basic Information Top
Gene Symbol:FAIM2 ( KIAA0950,LFG,LFG2,NGP35,NMP35,TMBIM2 )
Gene Full Name: Fas apoptotic inhibitory molecule 2
Band: 12q13.12
Quick LinksEntrez ID:23017; OMIM: 604306; Uniprot ID:FAIM2_HUMAN; ENSEMBL ID: ENSG00000135472; HGNC ID: 17067
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus11 / 56401219
neonate0 / 310970 
infant1 / 2362042
juvenile2 / 5555635
adult129 / 193912166
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor2 / 2638457
glioma18 / 106883168
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia7 / 9725071
normal257 / 336030776
ovarian tumor1 / 7668213
pancreatic tumor15 / 104616143
primitive neuroectodermal tumor of the CNS20 / 125680159
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain274 / 1100989248
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye16 / 21105475
heart1 / 8962611
intestine5 / 23447221
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle2 / 10771518
nerve3 / 15768190
ovary1 / 1020519
pancreas16 / 21481274
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis3 / 3304429
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203618_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.95
Adipocyte9
AdrenalCortex10.75
Adrenalgland8
Amygdala69.25
Appendix9
AtrioventricularNode8.6
BDCA4+_DentriticCells10.35
Bonemarrow8.9
BronchialEpithelialCells7.85
CD105+_Endothelial8.65
CD14+_Monocytes9.8
CD19+_BCells(neg._sel.)9.35
CD33+_Myeloid11.2
CD34+11.05
CD4+_Tcells10.15
CD56+_NKCells11.15
CD71+_EarlyErythroid9.65
CD8+_Tcells7.7
CardiacMyocytes11.15
Caudatenucleus48.6
Cerebellum25.5
CerebellumPeduncles99.2
CiliaryGanglion6.85
CingulateCortex195.85
Colorectaladenocarcinoma8.95
DorsalRootGanglion13.7
FetalThyroid8.35
Fetalbrain21.75
Fetalliver6.95
Fetallung6.5
GlobusPallidus75.55
Heart11.2
Hypothalamus94.05
Kidney6.9
Leukemia_chronicMyelogenousK-5627.85
Leukemia_promyelocytic-HL-607.6
Leukemialymphoblastic(MOLT-4)7.45
Liver11.7
Lung9.05
Lymphnode7
Lymphoma_burkitts(Daudi)11.45
Lymphoma_burkitts(Raji)12.4
MedullaOblongata99
OccipitalLobe122.9
OlfactoryBulb25.45
Ovary7.35
Pancreas6.55
PancreaticIslet9.65
ParietalLobe134.75
Pituitary9.85
Placenta7.95
Pons112.1
PrefrontalCortex356.85
Prostate9.55
Salivarygland7.2
SkeletalMuscle12.95
Skin6.7
SmoothMuscle9.9
Spinalcord45.7
SubthalamicNucleus100.6
SuperiorCervicalGanglion9.95
TemporalLobe95.05
Testis6.7
TestisGermCell7.3
TestisIntersitial7.8
TestisLeydigCell8.4
TestisSeminiferousTubule7.6
Thalamus113.05
Thymus6.4
Thyroid9.9
Tongue8.3
Tonsil8.75
Trachea7.25
TrigeminalGanglion8.7
Uterus7
UterusCorpus7.55
WholeBlood9.95
Wholebrain94.55
colon8
pineal_day11.52
pineal_night10.74
retina17.425
small_intestine7.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P139891
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.79 ± 0.72
Basal Forebrain7.29 ± 0.34
Basal Part of Pons8.13 ± 0.4
Cerebellar Cortex7.75 ± 0.48
Cerebellar Nuclei7.69 ± 0.36
Claustrum6.52 ± 0.73
Epithalamus7.6 ± 0.73
Frontal Lobe7.8 ± 0.5
Globus Pallidus6.7 ± 0.34
Hypothalamus8.34 ± 0.67
Insula7.76 ± 0.42
Limbic Lobe7.17 ± 0.67
Mesencephalon7.29 ± 0.63
Myelencephalon7.42 ± 0.75
Occipital Lobe6.8 ± 0.67
Parietal Lobe7.46 ± 0.66
Pontine Tegmentum7.46 ± 0.59
Striatum6.65 ± 0.54
Subthalamus8.09 ± 0.4
Temporal Lobe7.68 ± 0.56
Thalamus7.55 ± 0.49
White Matter7.22 ± 0.46
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Faim2CBCerebellum100
100
Faim2CTXCerebral cortex100
100
Faim2HIPHippocampal region100
100
Faim2HPFHippocampal formation100
100
Faim2HYHypothalamus100
100
Faim2LSXLateral septal complex100
100
Faim2MBMidbrain100
100
Faim2MYMedulla100
100
Faim2OLFOlfactory bulb100
100
Faim2PPons100
100
Faim2PALPallidum100
100
Faim2RHPRetrohippocampal region100
100
Faim2sAMYStriatum-like amygdalar nuclei100
100
Faim2STRStriatum100
100
Faim2STRdStriatum dorsal region86.91
91.28
Faim2STRvStriatum ventral region100
100
Faim2THThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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