AutismKB 2.0

Annotation Detail for MYO16


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Basic Information Top
Gene Symbol:MYO16 ( KIAA0865,MYR8,Myo16b )
Gene Full Name: myosin XVI
Band: 13q33.3
Quick LinksEntrez ID:23026; OMIM: NA; Uniprot ID:MYO16_HUMAN; ENSEMBL ID: ENSG00000041515; HGNC ID: 29822
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus12 / 56401221
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult3 / 19391211
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal23 / 33603076
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow1 / 4880120
brain11 / 11009899
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver1 / 2077434
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis6 / 33044218
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215119_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.45
Adipocyte3.9
AdrenalCortex4.2
Adrenalgland3.35
Amygdala7.55
Appendix5.95
AtrioventricularNode3.1
BDCA4+_DentriticCells4.3
Bonemarrow4
BronchialEpithelialCells3.95
CD105+_Endothelial4
CD14+_Monocytes4.2
CD19+_BCells(neg._sel.)4.2
CD33+_Myeloid5.05
CD34+5.05
CD4+_Tcells4.25
CD56+_NKCells4.7
CD71+_EarlyErythroid3.7
CD8+_Tcells3.8
CardiacMyocytes5.2
Caudatenucleus3.55
Cerebellum3.2
CerebellumPeduncles5.35
CiliaryGanglion2.85
CingulateCortex4.05
Colorectaladenocarcinoma3.95
DorsalRootGanglion3.05
FetalThyroid3.85
Fetalbrain86.35
Fetalliver3.45
Fetallung3.25
GlobusPallidus2.95
Heart5.1
Hypothalamus4.35
Kidney3.3
Leukemia_chronicMyelogenousK-5623.55
Leukemia_promyelocytic-HL-603.5
Leukemialymphoblastic(MOLT-4)3.15
Liver5.35
Lung4.3
Lymphnode3.4
Lymphoma_burkitts(Daudi)5.05
Lymphoma_burkitts(Raji)5.6
MedullaOblongata3.75
OccipitalLobe3.6
OlfactoryBulb3.1
Ovary2.6
Pancreas3.2
PancreaticIslet4.25
ParietalLobe4.65
Pituitary4.65
Placenta4.1
Pons4.1
PrefrontalCortex5
Prostate4.55
Salivarygland3.2
SkeletalMuscle4.85
Skin3.05
SmoothMuscle4.45
Spinalcord4.2
SubthalamicNucleus3.65
SuperiorCervicalGanglion5.7
TemporalLobe6.4
Testis3.4
TestisGermCell3.3
TestisIntersitial3.3
TestisLeydigCell4.1
TestisSeminiferousTubule3.4
Thalamus4
Thymus3.1
Thyroid4.95
Tongue3.9
Tonsil3.95
Trachea3.3
TrigeminalGanglion5.4
Uterus3.25
UterusCorpus3.6
WholeBlood4.35
Wholebrain3.7
colon4
pineal_day9.62
pineal_night16.02
retina4.775
small_intestine3.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P229234
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.58 ± 0.32
Basal Forebrain5.56 ± 0.34
Basal Part of Pons5.7 ± 0.55
Cerebellar Cortex6.1 ± 0.42
Cerebellar Nuclei6.49 ± 0.67
Claustrum5.19 ± 0.71
Epithalamus6.48 ± 0.48
Frontal Lobe6.14 ± 0.73
Globus Pallidus5.7 ± 0.78
Hypothalamus5.73 ± 0.7
Insula6.38 ± 0.43
Limbic Lobe6.4 ± 0.9
Mesencephalon5.66 ± 0.65
Myelencephalon5.9 ± 0.82
Occipital Lobe5.59 ± 0.69
Parietal Lobe5.85 ± 0.53
Pontine Tegmentum6.25 ± 0.86
Striatum4.46 ± 0.99
Subthalamus7.51 ± 0.26
Temporal Lobe6.54 ± 0.49
Thalamus5.75 ± 0.5
White Matter4.08 ± 0.87
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
C230040D10RikCBCerebellum10.13
11.38
C230040D10RikCTXCerebral cortex6.2
4.5
C230040D10RikHIPHippocampal region6.4
7.18
C230040D10RikHPFHippocampal formation5.71
5.62
C230040D10RikHYHypothalamus1.87
1.5
C230040D10RikLSXLateral septal complex2.31
1.51
C230040D10RikMBMidbrain4.83
4.76
C230040D10RikMYMedulla5.35
5.28
C230040D10RikOLFOlfactory bulb31.73
44.44
C230040D10RikPPons3.74
3.78
C230040D10RikPALPallidum4.98
4.52
C230040D10RikRHPRetrohippocampal region4.91
3.82
C230040D10RiksAMYStriatum-like amygdalar nuclei2.65
2.06
C230040D10RikSTRStriatum2.59
2.11
C230040D10RikSTRdStriatum dorsal region1.07
0.82
C230040D10RikSTRvStriatum ventral region9.93
7.68
C230040D10RikTHThalamus5.03
5.92
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018