AutismKB 2.0

Annotation Detail for WDTC1


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Basic Information Top
Gene Symbol:WDTC1 ( ADP,DCAF9,KIAA1037 )
Gene Full Name: WD and tetratricopeptide repeats 1
Band: 1p36.11
Quick LinksEntrez ID:23038; OMIM: NA; Uniprot ID:WDTC1_HUMAN; ENSEMBL ID: ENSG00000142784; HGNC ID: 29175
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus25 / 56401244
neonate1 / 3109732
infant0 / 236200 
juvenile2 / 5555635
adult101 / 193912152
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor3 / 3436687
chondrosarcoma5 / 8282360
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor21 / 26384579
glioma5 / 10688346
head and neck tumor11 / 13630280
kidney tumor3 / 6895943
leukemia3 / 9584231
liver tumor2 / 9635920
lung tumor9 / 10312787
lymphoma33 / 71755459
non-neoplasia5 / 9725051
normal202 / 336030760
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer6 / 10268058
retinoblastoma12 / 46356258
skin tumor3 / 12494924
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites3 / 4001574
bladder0 / 297570 
blood7 / 12347856
bone4 / 7165555
bone marrow0 / 488010 
brain86 / 110098978
cervix3 / 4817162
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye28 / 211054132
heart10 / 89626111
intestine5 / 23447221
kidney5 / 21177723
larynx1 / 2414541
liver2 / 2077439
lung16 / 33697447
lymph33 / 44270745
lymph node10 / 91610109
mammary gland8 / 15327152
mouth2 / 6705229
muscle7 / 10771564
nerve2 / 15768126
ovary3 / 10205129
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta8 / 28082528
prostate7 / 18934536
salivary gland3 / 20155148
skin8 / 21057437
spleen0 / 539520 
stomach3 / 9661931
testis49 / 330442148
thymus11 / 81131135
thyroid10 / 47473210
tonsil0 / 169990 
trachea8 / 52413152
umbilical cord3 / 13680219
uterus10 / 23287842
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 40829_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.35
Adipocyte5.6
AdrenalCortex9
Adrenalgland6.7
Amygdala7.5
Appendix7.65
AtrioventricularNode6.85
BDCA4+_DentriticCells8.6
Bonemarrow6.95
BronchialEpithelialCells4.75
CD105+_Endothelial8.05
CD14+_Monocytes8.25
CD19+_BCells(neg._sel.)10.2
CD33+_Myeloid10.2
CD34+10.25
CD4+_Tcells8.65
CD56+_NKCells18.75
CD71+_EarlyErythroid24.75
CD8+_Tcells7.45
CardiacMyocytes8.75
Caudatenucleus6.55
Cerebellum6
CerebellumPeduncles7.25
CiliaryGanglion5.2
CingulateCortex7.5
Colorectaladenocarcinoma7.35
DorsalRootGanglion5.45
FetalThyroid7.1
Fetalbrain6.75
Fetalliver6.15
Fetallung6.2
GlobusPallidus5.75
Heart9.85
Hypothalamus7
Kidney5.75
Leukemia_chronicMyelogenousK-5626.2
Leukemia_promyelocytic-HL-607.25
Leukemialymphoblastic(MOLT-4)5.35
Liver9.35
Lung10.05
Lymphnode5.8
Lymphoma_burkitts(Daudi)7.8
Lymphoma_burkitts(Raji)10.9
MedullaOblongata6.7
OccipitalLobe6.25
OlfactoryBulb5.8
Ovary4.7
Pancreas5.5
PancreaticIslet7.4
ParietalLobe7.3
Pituitary7.85
Placenta6.2
Pons6.9
PrefrontalCortex12.5
Prostate9
Salivarygland6.4
SkeletalMuscle7.6
Skin5.75
SmoothMuscle7.15
Spinalcord7.9
SubthalamicNucleus6.2
SuperiorCervicalGanglion7.65
TemporalLobe6.8
Testis15
TestisGermCell15.45
TestisIntersitial8.6
TestisLeydigCell8.4
TestisSeminiferousTubule11.4
Thalamus7.4
Thymus7.45
Thyroid10.95
Tongue6.85
Tonsil6.65
Trachea5.7
TrigeminalGanglion7.35
Uterus5.35
UterusCorpus5.15
WholeBlood10.1
Wholebrain6.35
colon5
pineal_day37.04
pineal_night31.88
retina10.675
small_intestine3.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P86054
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.86 ± 0.63
Basal Forebrain5.34 ± 0.2
Basal Part of Pons5.34 ± 0.36
Cerebellar Cortex5.05 ± 0.37
Cerebellar Nuclei5.46 ± 0.41
Claustrum5.93 ± 0.65
Epithalamus4.59 ± 0.41
Frontal Lobe5.08 ± 0.49
Globus Pallidus5.83 ± 0.55
Hypothalamus4.87 ± 0.28
Insula5.08 ± 0.72
Limbic Lobe5.45 ± 0.61
Mesencephalon5.35 ± 0.57
Myelencephalon5.36 ± 0.58
Occipital Lobe5.77 ± 0.68
Parietal Lobe5.33 ± 0.52
Pontine Tegmentum5.2 ± 0.55
Striatum5.69 ± 0.57
Subthalamus4.98 ± 0.32
Temporal Lobe5.19 ± 0.49
Thalamus5.32 ± 0.46
White Matter5.82 ± 0.52
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Wdtc1CBCerebellum37.02
41.18
Wdtc1CTXCerebral cortex82.3
58.59
Wdtc1HIPHippocampal region48.55
67.13
Wdtc1HPFHippocampal formation56.19
60.95
Wdtc1HYHypothalamus17.51
12.86
Wdtc1LSXLateral septal complex24.74
17.21
Wdtc1MBMidbrain35.19
31.03
Wdtc1MYMedulla62.78
69.08
Wdtc1OLFOlfactory bulb64.4
48.62
Wdtc1PPons44.85
50.57
Wdtc1PALPallidum22.15
19.02
Wdtc1RHPRetrohippocampal region71.77
54.54
Wdtc1sAMYStriatum-like amygdalar nuclei23.52
15.57
Wdtc1STRStriatum40.49
27.1
Wdtc1STRdStriatum dorsal region45.12
30.33
Wdtc1STRvStriatum ventral region38.83
25.26
Wdtc1THThalamus23.89
18.77
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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