AutismKB 2.0

Annotation Detail for XPO7


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Basic Information Top
Gene Symbol:XPO7 ( EXP7,KIAA0745,RANBP16 )
Gene Full Name: exportin 7
Band: 8p21.3
Quick LinksEntrez ID:23039; OMIM: 606140; Uniprot ID:XPO7_HUMAN; ENSEMBL ID: ENSG00000130227; HGNC ID: 14108
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst4 / 6231964
fetus114 / 564012202
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult139 / 193912171
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor10 / 94178106
cervical tumor3 / 3436687
chondrosarcoma9 / 82823108
colorectal tumor9 / 11424678
esophageal tumor1 / 1729057
gastrointestinal tumor12 / 119369100
germ cell tumor12 / 26384545
glioma9 / 10688384
head and neck tumor11 / 13630280
kidney tumor5 / 6895972
leukemia11 / 95842114
liver tumor0 / 963590 
lung tumor5 / 10312748
lymphoma1 / 7175513
non-neoplasia4 / 9725041
normal299 / 336030788
ovarian tumor9 / 76682117
pancreatic tumor11 / 104616105
primitive neuroectodermal tumor of the CNS12 / 12568095
prostate cancer7 / 10268068
retinoblastoma6 / 46356129
skin tumor9 / 12494972
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites2 / 4001549
bladder0 / 297570 
blood8 / 12347864
bone11 / 71655153
bone marrow4 / 4880181
brain74 / 110098967
cervix3 / 4817162
connective tissue8 / 14925553
ear3 / 16212185
embryonic tissue15 / 21572269
esophagus1 / 2020949
eye21 / 21105499
heart6 / 8962666
intestine18 / 23447276
kidney11 / 21177751
larynx2 / 2414582
liver8 / 20774338
lung23 / 33697468
lymph1 / 4427022
lymph node11 / 91610120
mammary gland14 / 15327191
mouth5 / 6705274
muscle5 / 10771546
nerve1 / 1576863
ovary12 / 102051117
pancreas16 / 21481274
parathyroid6 / 20539292
pharynx1 / 4132824
pituitary gland4 / 16585241
placenta8 / 28082528
prostate9 / 18934547
salivary gland0 / 201550 
skin23 / 210574109
spleen5 / 5395292
stomach18 / 96619186
testis45 / 330442136
thymus6 / 8113173
thyroid4 / 4747384
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus11 / 23287847
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212166_at
Cell line Expression level Expression bar
721_B_lymphoblasts168.95
Adipocyte109.25
AdrenalCortex120.65
Adrenalgland91.55
Amygdala112.85
Appendix109.7
AtrioventricularNode91.4
BDCA4+_DentriticCells92.75
Bonemarrow298.55
BronchialEpithelialCells104.8
CD105+_Endothelial129
CD14+_Monocytes113.4
CD19+_BCells(neg._sel.)92.85
CD33+_Myeloid135.5
CD34+173.85
CD4+_Tcells102.6
CD56+_NKCells101.2
CD71+_EarlyErythroid4245.55
CD8+_Tcells96
CardiacMyocytes127.25
Caudatenucleus99
Cerebellum124.1
CerebellumPeduncles137.95
CiliaryGanglion103.3
CingulateCortex113
Colorectaladenocarcinoma117.7
DorsalRootGanglion124.3
FetalThyroid114.35
Fetalbrain144.35
Fetalliver520.75
Fetallung130.05
GlobusPallidus103.45
Heart132.45
Hypothalamus122.05
Kidney104.85
Leukemia_chronicMyelogenousK-562155.85
Leukemia_promyelocytic-HL-60111.4
Leukemialymphoblastic(MOLT-4)120.85
Liver142.5
Lung115.7
Lymphnode105.9
Lymphoma_burkitts(Daudi)147.65
Lymphoma_burkitts(Raji)131.1
MedullaOblongata123.7
OccipitalLobe107.6
OlfactoryBulb97.9
Ovary72.1
Pancreas86.6
PancreaticIslet121.55
ParietalLobe120.75
Pituitary135.4
Placenta115.15
Pons118.95
PrefrontalCortex137.85
Prostate124.05
Salivarygland87.9
SkeletalMuscle134.25
Skin115.75
SmoothMuscle125.95
Spinalcord114.4
SubthalamicNucleus144.6
SuperiorCervicalGanglion188.25
TemporalLobe129.45
Testis96.5
TestisGermCell111.25
TestisIntersitial91.85
TestisLeydigCell114.7
TestisSeminiferousTubule95.05
Thalamus110.4
Thymus88.5
Thyroid121.2
Tongue107.55
Tonsil106.4
Trachea89.1
TrigeminalGanglion123.7
Uterus90.45
UterusCorpus105
WholeBlood124.7
Wholebrain76.9
colon110.55
pineal_day177.14
pineal_night195.94
retina162.625
small_intestine106.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P146237
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.37 ± 0.21
Basal Forebrain8.07 ± 0.19
Basal Part of Pons7.83 ± 0.22
Cerebellar Cortex7.81 ± 0.22
Cerebellar Nuclei8.01 ± 0.3
Claustrum8.5 ± 0.31
Epithalamus7.82 ± 0.16
Frontal Lobe8 ± 0.31
Globus Pallidus8.05 ± 0.18
Hypothalamus7.86 ± 0.34
Insula8 ± 0.27
Limbic Lobe8.28 ± 0.29
Mesencephalon8.03 ± 0.31
Myelencephalon8.02 ± 0.3
Occipital Lobe8.15 ± 0.25
Parietal Lobe8.12 ± 0.36
Pontine Tegmentum8.12 ± 0.25
Striatum8.3 ± 0.31
Subthalamus7.87 ± 0.2
Temporal Lobe8.06 ± 0.28
Thalamus7.9 ± 0.24
White Matter8.28 ± 0.6
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Xpo7CBCerebellum6.18
9.95
Xpo7CTXCerebral cortex52.36
45.69
Xpo7HIPHippocampal region51.4
95.05
Xpo7HPFHippocampal formation57.75
85.38
Xpo7HYHypothalamus30.54
27.94
Xpo7LSXLateral septal complex9.63
8.14
Xpo7MBMidbrain13.36
15.82
Xpo7MYMedulla4.85
8.39
Xpo7OLFOlfactory bulb34.62
35.22
Xpo7PPons14.01
20.67
Xpo7PALPallidum20.41
22.45
Xpo7RHPRetrohippocampal region74.46
72.06
Xpo7sAMYStriatum-like amygdalar nuclei88.42
75.16
Xpo7STRStriatum47.49
38.79
Xpo7STRdStriatum dorsal region52.4
42.13
Xpo7STRvStriatum ventral region22.26
19.73
Xpo7THThalamus29.66
29.81
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00032317 17 757 773 AIELWYHDPACTTPVLK Peptide Atlas
XPO7_HUMAN_2 26 2 27 ADHVQSLAQLENLCKQLYETTDTTTR PRIDE
XPO7_HUMAN_774 9 774 782 LMAELVHNR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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