AutismKB 2.0

Annotation Detail for KIF21B


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Basic Information Top
Gene Symbol:KIF21B ( FLJ16314 )
Gene Full Name: kinesin family member 21B
Band: 1q32.1
Quick LinksEntrez ID:23046; OMIM: 608322; Uniprot ID:KI21B_HUMAN; ENSEMBL ID: ENSG00000116852; HGNC ID: 29442
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus63 / 564012111
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult53 / 193912127
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor10 / 26384537
glioma9 / 10688384
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia7 / 9584273
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal151 / 336030744
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma10 / 46356215
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood14 / 123478113
bone0 / 716550 
bone marrow1 / 4880120
brain95 / 110098986
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye27 / 211054127
heart0 / 896260 
intestine4 / 23447217
kidney2 / 2117779
larynx0 / 241450 
liver2 / 2077439
lung2 / 3369745
lymph0 / 442700 
lymph node9 / 9161098
mammary gland1 / 1532716
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen2 / 5395237
stomach2 / 9661920
testis15 / 33044245
thymus2 / 8113124
thyroid3 / 4747363
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204411_at
Cell line Expression level Expression bar
721_B_lymphoblasts55.85
Adipocyte14.25
AdrenalCortex15.95
Adrenalgland15.6
Amygdala62.65
Appendix22.25
AtrioventricularNode9.35
BDCA4+_DentriticCells15.4
Bonemarrow27.05
BronchialEpithelialCells9.5
CD105+_Endothelial8.9
CD14+_Monocytes12.65
CD19+_BCells(neg._sel.)31.7
CD33+_Myeloid20.95
CD34+17.6
CD4+_Tcells57
CD56+_NKCells60.55
CD71+_EarlyErythroid8.2
CD8+_Tcells68.3
CardiacMyocytes14.85
Caudatenucleus20.25
Cerebellum18.05
CerebellumPeduncles18.75
CiliaryGanglion10.75
CingulateCortex49.2
Colorectaladenocarcinoma13.8
DorsalRootGanglion13.55
FetalThyroid10.35
Fetalbrain533.25
Fetalliver13.75
Fetallung10.6
GlobusPallidus18
Heart31.35
Hypothalamus26.3
Kidney14.85
Leukemia_chronicMyelogenousK-56216.9
Leukemia_promyelocytic-HL-6014.2
Leukemialymphoblastic(MOLT-4)25.1
Liver23.15
Lung14
Lymphnode16.35
Lymphoma_burkitts(Daudi)40.5
Lymphoma_burkitts(Raji)32.8
MedullaOblongata31.2
OccipitalLobe27.2
OlfactoryBulb10.55
Ovary8.1
Pancreas10.6
PancreaticIslet14.8
ParietalLobe31.85
Pituitary17.35
Placenta15.05
Pons23.9
PrefrontalCortex42.5
Prostate16.75
Salivarygland7.15
SkeletalMuscle17.65
Skin12.1
SmoothMuscle9.05
Spinalcord21.1
SubthalamicNucleus23
SuperiorCervicalGanglion21.65
TemporalLobe24.3
Testis13.65
TestisGermCell12
TestisIntersitial11.85
TestisLeydigCell16.75
TestisSeminiferousTubule13.1
Thalamus17.05
Thymus22.45
Thyroid18.8
Tongue16.5
Tonsil24.05
Trachea12.7
TrigeminalGanglion16
Uterus10.05
UterusCorpus13.95
WholeBlood32.8
Wholebrain30.9
colon14.85
pineal_day230.48
pineal_night173.18
retina24.075
small_intestine12.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1474_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.31 ± 0.63
Basal Forebrain4.69 ± 0.28
Basal Part of Pons4.88 ± 0.43
Cerebellar Cortex4.19 ± 0.37
Cerebellar Nuclei3.96 ± 0.76
Claustrum4.61 ± 0.76
Epithalamus4.2 ± 0.68
Frontal Lobe4.84 ± 0.64
Globus Pallidus3.83 ± 0.81
Hypothalamus4.3 ± 0.75
Insula5.02 ± 0.35
Limbic Lobe5.19 ± 0.47
Mesencephalon4.57 ± 0.67
Myelencephalon4.63 ± 0.64
Occipital Lobe4.42 ± 0.49
Parietal Lobe4.61 ± 0.57
Pontine Tegmentum4.61 ± 0.68
Striatum4.02 ± 0.97
Subthalamus4.38 ± 0.4
Temporal Lobe5.2 ± 0.45
Thalamus4.46 ± 0.45
White Matter3.36 ± 0.66
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Kif21bCBCerebellum3.23
3.35
Kif21bCTXCerebral cortex32.96
22.58
Kif21bHIPHippocampal region11.12
11.02
Kif21bHPFHippocampal formation15.39
13.66
Kif21bHYHypothalamus1.44
1.01
Kif21bLSXLateral septal complex2.9
2.34
Kif21bMBMidbrain4.25
3.72
Kif21bMYMedulla7.93
8.1
Kif21bOLFOlfactory bulb24.6
18.56
Kif21bPPons3.59
3.51
Kif21bPALPallidum2.24
1.85
Kif21bRHPRetrohippocampal region23.74
18.34
Kif21bsAMYStriatum-like amygdalar nuclei4.85
3.53
Kif21bSTRStriatum2.16
1.64
Kif21bSTRdStriatum dorsal region1.6
1.34
Kif21bSTRvStriatum ventral region2.5
1.51
Kif21bTHThalamus2.08
1.75
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
KI21B_HUMAN_949 10 949 958 ELFLLQEALR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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