AutismKB 2.0

Annotation Detail for FOXM1


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Basic Information Top
Gene Symbol:FOXM1 ( FKHL16,FOXM1B,HFH-11,HFH11,HNF-3,INS-1,MPHOSPH2,MPP-2,MPP2,PIG29,TGT3,TRIDENT )
Gene Full Name: forkhead box M1
Band: 12p13.33
Quick LinksEntrez ID:2305; OMIM: 602341; Uniprot ID:FOXM1_HUMAN; ENSEMBL ID: ENSG00000111206; HGNC ID: 3818
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst9 / 62319144
fetus13 / 56401223
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult58 / 193912129
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma1 / 1747557
breast (mammary gland) tumor8 / 9417884
cervical tumor6 / 34366174
chondrosarcoma3 / 8282336
colorectal tumor13 / 114246113
esophageal tumor2 / 17290115
gastrointestinal tumor5 / 11936941
germ cell tumor37 / 263845140
glioma5 / 10688346
head and neck tumor5 / 13630236
kidney tumor7 / 68959101
leukemia3 / 9584231
liver tumor3 / 9635931
lung tumor14 / 103127135
lymphoma27 / 71755376
non-neoplasia1 / 9725010
normal58 / 336030717
ovarian tumor3 / 7668239
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS12 / 12568095
prostate cancer9 / 10268087
retinoblastoma6 / 46356129
skin tumor17 / 124949136
soft tissue/muscle tissue tumor25 / 125191199
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites1 / 4001524
bladder1 / 2975733
blood2 / 12347816
bone3 / 7165541
bone marrow0 / 488010 
brain13 / 110098911
cervix6 / 48171124
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue26 / 215722120
esophagus2 / 2020998
eye6 / 21105428
heart2 / 8962622
intestine20 / 23447285
kidney7 / 21177733
larynx2 / 2414582
liver5 / 20774324
lung16 / 33697447
lymph27 / 44270609
lymph node3 / 9161032
mammary gland9 / 15327158
mouth0 / 670520 
muscle6 / 10771555
nerve0 / 157680 
ovary13 / 102051127
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta18 / 28082564
prostate9 / 18934547
salivary gland3 / 20155148
skin17 / 21057480
spleen0 / 539520 
stomach2 / 9661920
testis13 / 33044239
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus24 / 232878103
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202580_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts126.5
Adipocyte2.7
AdrenalCortex2.75
Adrenalgland2.25
Amygdala2.9
Appendix2.75
AtrioventricularNode2.05
BDCA4+_DentriticCells3.4
Bonemarrow3.95
BronchialEpithelialCells4.6
CD105+_Endothelial87.75
CD14+_Monocytes2.9
CD19+_BCells(neg._sel.)2.95
CD33+_Myeloid8.25
CD34+36.3
CD4+_Tcells3.05
CD56+_NKCells3.3
CD71+_EarlyErythroid130.8
CD8+_Tcells2.7
CardiacMyocytes9.25
Caudatenucleus2.4
Cerebellum2.15
CerebellumPeduncles3.05
CiliaryGanglion1.9
CingulateCortex2.8
Colorectaladenocarcinoma68.95
DorsalRootGanglion2
FetalThyroid2.65
Fetalbrain2.75
Fetalliver4.55
Fetallung2.3
GlobusPallidus1.95
Heart3.4
Hypothalamus3
Kidney2.15
Leukemia_chronicMyelogenousK-5622.65
Leukemia_promyelocytic-HL-6024.8
Leukemialymphoblastic(MOLT-4)98.5
Liver3.55
Lung3.05
Lymphnode2.4
Lymphoma_burkitts(Daudi)128.6
Lymphoma_burkitts(Raji)6.15
MedullaOblongata2.5
OccipitalLobe2.45
OlfactoryBulb2.15
Ovary1.75
Pancreas2.2
PancreaticIslet2.9
ParietalLobe2.8
Pituitary3.15
Placenta2.85
Pons2.55
PrefrontalCortex3.4
Prostate3.25
Salivarygland2.2
SkeletalMuscle3
Skin2.05
SmoothMuscle3.15
Spinalcord2.9
SubthalamicNucleus2.45
SuperiorCervicalGanglion3.05
TemporalLobe2.45
Testis27.85
TestisGermCell8.7
TestisIntersitial9.75
TestisLeydigCell5.8
TestisSeminiferousTubule8.75
Thalamus2.75
Thymus28.65
Thyroid3.45
Tongue2.65
Tonsil2.65
Trachea2.25
TrigeminalGanglion2.65
Uterus2.25
UterusCorpus2.4
WholeBlood3.05
Wholebrain2.35
colon2.75
pineal_day3.44
pineal_night3.32
retina3.35
small_intestine2.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15073_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.15 ± 1.09
Basal Forebrain1.65 ± 0.22
Basal Part of Pons1.49 ± 0.35
Cerebellar Cortex1.63 ± 0.72
Cerebellar Nuclei2.01 ± 0.72
Claustrum2.52 ± 0.85
Epithalamus1.43 ± 0.69
Frontal Lobe1.63 ± 0.64
Globus Pallidus2.2 ± 0.29
Hypothalamus1.8 ± 0.58
Insula1.59 ± 0.37
Limbic Lobe1.79 ± 0.72
Mesencephalon1.88 ± 0.66
Myelencephalon1.83 ± 0.67
Occipital Lobe1.87 ± 0.71
Parietal Lobe1.82 ± 0.75
Pontine Tegmentum1.86 ± 0.86
Striatum1.94 ± 0.68
Subthalamus1.96 ± 0.61
Temporal Lobe1.69 ± 0.74
Thalamus1.81 ± 0.65
White Matter2.29 ± 0.5
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Foxm1CBCerebellum1.08
1.78
Foxm1CTXCerebral cortex0.15
0.16
Foxm1HIPHippocampal region0.08
0.13
Foxm1HPFHippocampal formation0.13
0.17
Foxm1HYHypothalamus0.22
0.34
Foxm1LSXLateral septal complex0.64
1.85
Foxm1MBMidbrain0.24
0.55
Foxm1MYMedulla0.65
0.67
Foxm1OLFOlfactory bulb0.33
0.45
Foxm1PPons0.41
0.45
Foxm1PALPallidum0.09
0.14
Foxm1RHPRetrohippocampal region0.24
0.26
Foxm1sAMYStriatum-like amygdalar nuclei0.05
0.05
Foxm1STRStriatum0.15
0.23
Foxm1STRdStriatum dorsal region0.12
0.1
Foxm1STRvStriatum ventral region0.05
0.02
Foxm1THThalamus0.07
0.06
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018