AutismKB 2.0

Annotation Detail for ENDOD1


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Basic Information Top
Gene Symbol:ENDOD1 ( KIAA0830,MGC88092 )
Gene Full Name: endonuclease domain containing 1
Band: 11q21
Quick LinksEntrez ID:23052; OMIM: NA; Uniprot ID:ENDD1_HUMAN; ENSEMBL ID: ENSG00000149218; HGNC ID: 29129
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst0 / 623190 
fetus21 / 56401237
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult84 / 193912143
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma8 / 8282396
colorectal tumor2 / 11424617
esophageal tumor1 / 1729057
gastrointestinal tumor2 / 11936916
germ cell tumor4 / 26384515
glioma6 / 10688356
head and neck tumor3 / 13630222
kidney tumor5 / 6895972
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia3 / 9725030
normal165 / 336030749
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer14 / 102680136
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland5 / 33197150
ascites0 / 400150 
bladder2 / 2975767
blood1 / 1234788
bone3 / 7165541
bone marrow1 / 4880120
brain72 / 110098965
cervix0 / 481710 
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus1 / 2020949
eye9 / 21105442
heart3 / 8962633
intestine5 / 23447221
kidney20 / 21177794
larynx0 / 241450 
liver1 / 2077434
lung9 / 33697426
lymph0 / 442700 
lymph node5 / 9161054
mammary gland4 / 15327126
mouth1 / 6705214
muscle3 / 10771527
nerve1 / 1576863
ovary2 / 10205119
pancreas4 / 21481218
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland3 / 16585180
placenta6 / 28082521
prostate27 / 189345142
salivary gland0 / 201550 
skin14 / 21057466
spleen2 / 5395237
stomach2 / 9661920
testis3 / 3304429
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212570_at
Cell line Expression level Expression bar
721_B_lymphoblasts10
Adipocyte4.95
AdrenalCortex5.1
Adrenalgland4.1
Amygdala6.7
Appendix4.95
AtrioventricularNode3.75
BDCA4+_DentriticCells8.4
Bonemarrow5.05
BronchialEpithelialCells5
CD105+_Endothelial12.05
CD14+_Monocytes5.1
CD19+_BCells(neg._sel.)19.6
CD33+_Myeloid7.85
CD34+27.85
CD4+_Tcells5.5
CD56+_NKCells6.25
CD71+_EarlyErythroid101.8
CD8+_Tcells5
CardiacMyocytes6.2
Caudatenucleus5.3
Cerebellum4
CerebellumPeduncles5.55
CiliaryGanglion3.45
CingulateCortex5.05
Colorectaladenocarcinoma5
DorsalRootGanglion3.85
FetalThyroid4.9
Fetalbrain5
Fetalliver4.1
Fetallung4.15
GlobusPallidus3.6
Heart6.2
Hypothalamus7.85
Kidney3.9
Leukemia_chronicMyelogenousK-5624.5
Leukemia_promyelocytic-HL-604.4
Leukemialymphoblastic(MOLT-4)4
Liver6.45
Lung6.5
Lymphnode4.15
Lymphoma_burkitts(Daudi)6.35
Lymphoma_burkitts(Raji)6.9
MedullaOblongata6.3
OccipitalLobe5.05
OlfactoryBulb4.85
Ovary3.35
Pancreas3.8
PancreaticIslet5.25
ParietalLobe5.3
Pituitary5.8
Placenta4.8
Pons4.75
PrefrontalCortex6.3
Prostate21.2
Salivarygland3.7
SkeletalMuscle6.65
Skin4.2
SmoothMuscle5.5
Spinalcord5.35
SubthalamicNucleus4.45
SuperiorCervicalGanglion5.6
TemporalLobe4.55
Testis4.3
TestisGermCell4.2
TestisIntersitial4.15
TestisLeydigCell4.65
TestisSeminiferousTubule4.3
Thalamus5.1
Thymus3.7
Thyroid6.8
Tongue4.8
Tonsil4.85
Trachea4.15
TrigeminalGanglion5.25
Uterus4.3
UterusCorpus5.9
WholeBlood5.5
Wholebrain14.8
colon7.05
pineal_day6.26
pineal_night6.32
retina6.1
small_intestine5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_249_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.59 ± 0.34
Basal Forebrain9.2 ± 0.33
Basal Part of Pons9.48 ± 0.23
Cerebellar Cortex8.97 ± 0.17
Cerebellar Nuclei9.79 ± 0.42
Claustrum8.93 ± 0.28
Epithalamus8.98 ± 0.45
Frontal Lobe9.07 ± 0.5
Globus Pallidus10.1 ± 0.33
Hypothalamus9.35 ± 0.22
Insula8.65 ± 0.3
Limbic Lobe8.83 ± 0.47
Mesencephalon9.3 ± 0.41
Myelencephalon9.08 ± 0.43
Occipital Lobe9.22 ± 0.41
Parietal Lobe9.05 ± 0.39
Pontine Tegmentum9.12 ± 0.35
Striatum9.24 ± 0.45
Subthalamus9.51 ± 0.27
Temporal Lobe8.84 ± 0.32
Thalamus9.31 ± 0.25
White Matter11 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Endod1CBCerebellum24.15
39.14
Endod1CTXCerebral cortex28.37
27.24
Endod1HIPHippocampal region32.01
46.13
Endod1HPFHippocampal formation31.9
39.12
Endod1HYHypothalamus71.2
72.07
Endod1LSXLateral septal complex42.14
34.72
Endod1MBMidbrain74.73
85.02
Endod1MYMedulla75.9
100
Endod1OLFOlfactory bulb24.06
21
Endod1PPons82.12
100
Endod1PALPallidum67.23
78.82
Endod1RHPRetrohippocampal region33.6
31.46
Endod1sAMYStriatum-like amygdalar nuclei44.28
40.09
Endod1STRStriatum23.38
22
Endod1STRdStriatum dorsal region17.82
17.45
Endod1STRvStriatum ventral region22.05
20.72
Endod1THThalamus44.14
45.83
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000562 24 185 208 ALTPQCGSGEDLYILTGTVPSDYR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018