AutismKB 2.0

Annotation Detail for NCOA6


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Basic Information Top
Gene Symbol:NCOA6 ( AIB3,ASC2,KIAA0181,NRC,PRIP,RAP250,TRBP )
Gene Full Name: nuclear receptor coactivator 6
Band: 20q11.22
Quick LinksEntrez ID:23054; OMIM: 605299; Uniprot ID:NCOA6_HUMAN; ENSEMBL ID: ENSG00000198646; HGNC ID: 15936
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus50 / 56401288
neonate0 / 310970 
infant0 / 236200 
juvenile7 / 55556125
adult140 / 193912172
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor10 / 11424687
esophageal tumor2 / 17290115
gastrointestinal tumor4 / 11936933
germ cell tumor12 / 26384545
glioma6 / 10688356
head and neck tumor23 / 136302168
kidney tumor3 / 6895943
leukemia8 / 9584283
liver tumor7 / 9635972
lung tumor3 / 10312729
lymphoma3 / 7175541
non-neoplasia3 / 9725030
normal175 / 336030752
ovarian tumor5 / 7668265
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer2 / 10268019
retinoblastoma3 / 4635664
skin tumor4 / 12494932
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites1 / 4001524
bladder1 / 2975733
blood6 / 12347848
bone3 / 7165541
bone marrow2 / 4880140
brain63 / 110098957
cervix1 / 4817120
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus2 / 2020998
eye8 / 21105437
heart4 / 8962644
intestine15 / 23447263
kidney10 / 21177747
larynx17 / 24145704
liver7 / 20774333
lung14 / 33697441
lymph3 / 4427067
lymph node3 / 9161032
mammary gland16 / 153271104
mouth4 / 6705259
muscle0 / 1077150 
nerve1 / 1576863
ovary6 / 10205158
pancreas10 / 21481246
parathyroid4 / 20539194
pharynx2 / 4132848
pituitary gland2 / 16585120
placenta18 / 28082564
prostate3 / 18934515
salivary gland0 / 201550 
skin7 / 21057433
spleen2 / 5395237
stomach4 / 9661941
testis11 / 33044233
thymus2 / 8113124
thyroid6 / 47473126
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus8 / 23287834
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208979_at
Cell line Expression level Expression bar
721_B_lymphoblasts38.8
Adipocyte7.6
AdrenalCortex9.6
Adrenalgland7.05
Amygdala16.1
Appendix9.15
AtrioventricularNode5.3
BDCA4+_DentriticCells66.05
Bonemarrow6.95
BronchialEpithelialCells10.5
CD105+_Endothelial33.15
CD14+_Monocytes42.55
CD19+_BCells(neg._sel.)35.95
CD33+_Myeloid105.75
CD34+73.45
CD4+_Tcells40.6
CD56+_NKCells134.15
CD71+_EarlyErythroid10.9
CD8+_Tcells55.9
CardiacMyocytes10.35
Caudatenucleus9.2
Cerebellum13.65
CerebellumPeduncles14.2
CiliaryGanglion4.1
CingulateCortex11.2
Colorectaladenocarcinoma29.85
DorsalRootGanglion4.5
FetalThyroid10.8
Fetalbrain85.85
Fetalliver6.35
Fetallung8.9
GlobusPallidus5.5
Heart8.3
Hypothalamus22.35
Kidney6.6
Leukemia_chronicMyelogenousK-5627
Leukemia_promyelocytic-HL-608.1
Leukemialymphoblastic(MOLT-4)31.35
Liver9.35
Lung14.95
Lymphnode9.2
Lymphoma_burkitts(Daudi)9.75
Lymphoma_burkitts(Raji)10.2
MedullaOblongata9.9
OccipitalLobe10.25
OlfactoryBulb8.4
Ovary6
Pancreas6.1
PancreaticIslet9.95
ParietalLobe8.45
Pituitary11
Placenta64.5
Pons8.3
PrefrontalCortex17.75
Prostate18.45
Salivarygland10.65
SkeletalMuscle11.05
Skin7.85
SmoothMuscle11.2
Spinalcord14.45
SubthalamicNucleus5.9
SuperiorCervicalGanglion7.5
TemporalLobe7.65
Testis18.65
TestisGermCell29.1
TestisIntersitial18.85
TestisLeydigCell14.55
TestisSeminiferousTubule16
Thalamus12.95
Thymus15.5
Thyroid22.5
Tongue9.6
Tonsil9.2
Trachea9.2
TrigeminalGanglion9.15
Uterus10
UterusCorpus8.7
WholeBlood14.95
Wholebrain11.6
colon9.85
pineal_day45.02
pineal_night35.5
retina26.525
small_intestine12.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10264_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.02 ± 0.32
Basal Forebrain5.95 ± 0.26
Basal Part of Pons5.82 ± 0.24
Cerebellar Cortex6.27 ± 0.18
Cerebellar Nuclei5.32 ± 0.5
Claustrum5.9 ± 0.44
Epithalamus5.85 ± 0.43
Frontal Lobe5.94 ± 0.37
Globus Pallidus5.68 ± 0.34
Hypothalamus5.59 ± 0.38
Insula6.01 ± 0.25
Limbic Lobe6.14 ± 0.32
Mesencephalon5.86 ± 0.39
Myelencephalon5.94 ± 0.34
Occipital Lobe5.91 ± 0.28
Parietal Lobe5.9 ± 0.38
Pontine Tegmentum5.86 ± 0.38
Striatum5.83 ± 0.29
Subthalamus5.68 ± 0.53
Temporal Lobe6.03 ± 0.34
Thalamus5.92 ± 0.27
White Matter6.6 ± 0.15
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ncoa6CBCerebellum22.56
27.47
Ncoa6CTXCerebral cortex40.74
30.39
Ncoa6HIPHippocampal region32.38
39.08
Ncoa6HPFHippocampal formation30.67
31.5
Ncoa6HYHypothalamus11.92
9.71
Ncoa6LSXLateral septal complex15.56
11.92
Ncoa6MBMidbrain14.06
14.2
Ncoa6MYMedulla13.48
13.29
Ncoa6OLFOlfactory bulb38.9
31.69
Ncoa6PPons13.29
13.69
Ncoa6PALPallidum9.26
7.77
Ncoa6RHPRetrohippocampal region28.25
21.85
Ncoa6sAMYStriatum-like amygdalar nuclei8.99
6.49
Ncoa6STRStriatum11.68
8.45
Ncoa6STRdStriatum dorsal region9.98
7.38
Ncoa6STRvStriatum ventral region17.48
11.34
Ncoa6THThalamus18.08
15.11
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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