AutismKB 2.0

Annotation Detail for ZNF609


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Basic Information Top
Gene Symbol:ZNF609 ( KIAA0295,MGC164858 )
Gene Full Name: zinc finger protein 609
Band: 15q22.1
Quick LinksEntrez ID:23060; OMIM: NA; Uniprot ID:ZN609_HUMAN; ENSEMBL ID: ENSG00000180357; HGNC ID: 29003
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult4 / 19391212
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult4 / 19391212
embryoid body4 / 7076156
blastocyst4 / 6231964
fetus19 / 56401233
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult75 / 193912138
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma4 / 10688337
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal5 / 33603071
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal4 / 33603071
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
adrenal tumor0 / 127940 
bladder carcinoma5 / 17475286
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor6 / 26384522
glioma4 / 10688337
head and neck tumor11 / 13630280
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma3 / 7175541
non-neoplasia0 / 972500 
normal89 / 336030726
ovarian tumor3 / 7668239
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer2 / 10268019
retinoblastoma9 / 46356194
skin tumor6 / 12494948
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain6 / 11009895
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites4 / 4001599
bladder1 / 2975733
blood2 / 12347816
bone6 / 7165583
bone marrow0 / 488010 
brain16 / 110098914
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye20 / 21105494
heart0 / 896260 
intestine6 / 23447225
kidney4 / 21177718
larynx10 / 24145414
liver1 / 2077434
lung8 / 33697423
lymph3 / 4427067
lymph node7 / 9161076
mammary gland7 / 15327145
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary4 / 10205139
pancreas5 / 21481223
parathyroid3 / 20539146
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta3 / 28082510
prostate7 / 18934536
salivary gland0 / 201550 
skin9 / 21057442
spleen0 / 539520 
stomach0 / 966190 
testis8 / 33044224
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus8 / 23287834
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212618_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.4
Adipocyte8.15
AdrenalCortex8.95
Adrenalgland7.15
Amygdala8.6
Appendix8.25
AtrioventricularNode7.15
BDCA4+_DentriticCells8.95
Bonemarrow8.8
BronchialEpithelialCells7.05
CD105+_Endothelial7.5
CD14+_Monocytes8.3
CD19+_BCells(neg._sel.)8.65
CD33+_Myeloid10.15
CD34+10.6
CD4+_Tcells8.8
CD56+_NKCells9.7
CD71+_EarlyErythroid7.6
CD8+_Tcells8.05
CardiacMyocytes10.9
Caudatenucleus7.4
Cerebellum6.65
CerebellumPeduncles9.3
CiliaryGanglion5.9
CingulateCortex9.4
Colorectaladenocarcinoma8.15
DorsalRootGanglion6.4
FetalThyroid8.05
Fetalbrain8.2
Fetalliver7.1
Fetallung6.2
GlobusPallidus6
Heart10.6
Hypothalamus8.9
Kidney6.85
Leukemia_chronicMyelogenousK-5627.45
Leukemia_promyelocytic-HL-607.25
Leukemialymphoblastic(MOLT-4)6.6
Liver10.85
Lung9.3
Lymphnode7.2
Lymphoma_burkitts(Daudi)11
Lymphoma_burkitts(Raji)11.55
MedullaOblongata7.65
OccipitalLobe7.45
OlfactoryBulb6.5
Ovary5.95
Pancreas6.65
PancreaticIslet8.75
ParietalLobe8.95
Pituitary9.65
Placenta7.7
Pons10.55
PrefrontalCortex10.05
Prostate9.5
Salivarygland9.35
SkeletalMuscle9.55
Skin6.8
SmoothMuscle9.35
Spinalcord8.75
SubthalamicNucleus7.45
SuperiorCervicalGanglion9.3
TemporalLobe7.5
Testis7.2
TestisGermCell7.1
TestisIntersitial6.9
TestisLeydigCell8.6
TestisSeminiferousTubule8.7
Thalamus8.6
Thymus6.5
Thyroid10.3
Tongue8.25
Tonsil8.8
Trachea7.65
TrigeminalGanglion10.75
Uterus6.7
UterusCorpus7.2
WholeBlood8.4
Wholebrain6.9
colon8.3
pineal_day10.32
pineal_night10.06
retina10.1
small_intestine8.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P176609
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.84 ± 0.17
Basal Forebrain10.9 ± 0.13
Basal Part of Pons10.61 ± 0.13
Cerebellar Cortex10.99 ± 0.19
Cerebellar Nuclei10.75 ± 0.26
Claustrum10.73 ± 0.21
Epithalamus11.02 ± 0.31
Frontal Lobe10.84 ± 0.27
Globus Pallidus11.42 ± 0.16
Hypothalamus10.7 ± 0.24
Insula10.96 ± 0.19
Limbic Lobe10.97 ± 0.28
Mesencephalon10.91 ± 0.26
Myelencephalon10.9 ± 0.26
Occipital Lobe11.02 ± 0.22
Parietal Lobe10.97 ± 0.22
Pontine Tegmentum10.92 ± 0.22
Striatum10.99 ± 0.32
Subthalamus10.98 ± 0.2
Temporal Lobe10.89 ± 0.2
Thalamus10.82 ± 0.22
White Matter11.93 ± 0.19
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfp609CBCerebellum20.46
21.24
Zfp609CTXCerebral cortex35.05
24.41
Zfp609HIPHippocampal region29.73
41.12
Zfp609HPFHippocampal formation33.85
37.41
Zfp609HYHypothalamus10.4
7.52
Zfp609LSXLateral septal complex10.83
7.34
Zfp609MBMidbrain13.38
11.02
Zfp609MYMedulla18.37
18.57
Zfp609OLFOlfactory bulb37.12
30.07
Zfp609PPons16.13
15.31
Zfp609PALPallidum9.79
8.22
Zfp609RHPRetrohippocampal region44.19
33.88
Zfp609sAMYStriatum-like amygdalar nuclei31.74
22.27
Zfp609STRStriatum15.12
10.53
Zfp609STRdStriatum dorsal region14.46
10.18
Zfp609STRvStriatum ventral region10.08
6.92
Zfp609THThalamus24.1
20.41
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00077362 17 125 141 SGDGANAGGLVAAIAPK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018