AutismKB 2.0

Annotation Detail for GGA2


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Basic Information Top
Gene Symbol:GGA2 ( FLJ20966,KIAA1080,VEAR )
Gene Full Name: golgi-associated, gamma adaptin ear containing, ARF binding protein 2
Band: 16p12.2
Quick LinksEntrez ID:23062; OMIM: 606005; Uniprot ID:GGA2_HUMAN; ENSEMBL ID: ENSG00000103365; HGNC ID: 16064
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst17 / 62319272
fetus79 / 564012140
neonate1 / 3109732
infant1 / 2362042
juvenile4 / 5555671
adult143 / 193912173
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor4 / 9417842
cervical tumor2 / 3436658
chondrosarcoma8 / 8282396
colorectal tumor6 / 11424652
esophageal tumor1 / 1729057
gastrointestinal tumor14 / 119369117
germ cell tumor27 / 263845102
glioma7 / 10688365
head and neck tumor22 / 136302161
kidney tumor9 / 68959130
leukemia6 / 9584262
liver tumor7 / 9635972
lung tumor6 / 10312758
lymphoma28 / 71755390
non-neoplasia5 / 9725051
normal390 / 3360307116
ovarian tumor3 / 7668239
pancreatic tumor11 / 104616105
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer5 / 10268048
retinoblastoma5 / 46356107
skin tumor6 / 12494948
soft tissue/muscle tissue tumor11 / 12519187
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites10 / 40015249
bladder2 / 2975767
blood13 / 123478105
bone3 / 7165541
bone marrow1 / 4880120
brain64 / 110098958
cervix5 / 48171103
connective tissue12 / 14925580
ear3 / 16212185
embryonic tissue36 / 215722166
esophagus1 / 2020949
eye33 / 211054156
heart9 / 89626100
intestine14 / 23447259
kidney19 / 21177789
larynx0 / 241450 
liver12 / 20774357
lung31 / 33697491
lymph21 / 44270474
lymph node79 / 91610862
mammary gland10 / 15327165
mouth7 / 67052104
muscle6 / 10771555
nerve3 / 15768190
ovary5 / 10205148
pancreas17 / 21481279
parathyroid2 / 2053997
pharynx2 / 4132848
pituitary gland2 / 16585120
placenta10 / 28082535
prostate20 / 189345105
salivary gland2 / 2015599
skin10 / 21057447
spleen11 / 53952203
stomach1 / 9661910
testis21 / 33044263
thymus23 / 81131283
thyroid15 / 47473315
tonsil10 / 16999588
trachea14 / 52413267
umbilical cord2 / 13680146
uterus21 / 23287890
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208915_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts19.5
Adipocyte5
AdrenalCortex5.1
Adrenalgland5.15
Amygdala5.35
Appendix5.5
AtrioventricularNode3.55
BDCA4+_DentriticCells33.45
Bonemarrow5.75
BronchialEpithelialCells7.05
CD105+_Endothelial6.95
CD14+_Monocytes5.1
CD19+_BCells(neg._sel.)30.8
CD33+_Myeloid11.8
CD34+9.35
CD4+_Tcells16.2
CD56+_NKCells7.05
CD71+_EarlyErythroid6.55
CD8+_Tcells11.1
CardiacMyocytes6.85
Caudatenucleus4.35
Cerebellum5.3
CerebellumPeduncles5.4
CiliaryGanglion3.3
CingulateCortex4.9
Colorectaladenocarcinoma5.1
DorsalRootGanglion3.85
FetalThyroid4.75
Fetalbrain5.7
Fetalliver6.15
Fetallung4.8
GlobusPallidus3.2
Heart6.3
Hypothalamus5.25
Kidney5.2
Leukemia_chronicMyelogenousK-5624.55
Leukemia_promyelocytic-HL-6010.8
Leukemialymphoblastic(MOLT-4)4.6
Liver6.85
Lung5.95
Lymphnode9.05
Lymphoma_burkitts(Daudi)22.1
Lymphoma_burkitts(Raji)8.8
MedullaOblongata4.45
OccipitalLobe4.15
OlfactoryBulb3.8
Ovary3.4
Pancreas3.95
PancreaticIslet8.05
ParietalLobe4.9
Pituitary7.5
Placenta5.15
Pons5.2
PrefrontalCortex5.95
Prostate8.4
Salivarygland4.35
SkeletalMuscle5.85
Skin3.95
SmoothMuscle5.75
Spinalcord5.3
SubthalamicNucleus3.95
SuperiorCervicalGanglion10.25
TemporalLobe4.65
Testis4.45
TestisGermCell4.4
TestisIntersitial4.05
TestisLeydigCell4.4
TestisSeminiferousTubule4.3
Thalamus4.75
Thymus7.25
Thyroid7
Tongue4.6
Tonsil10.95
Trachea9.15
TrigeminalGanglion7.05
Uterus4
UterusCorpus4.75
WholeBlood5.3
Wholebrain4.15
colon4.8
pineal_day6.46
pineal_night6.28
retina7.425
small_intestine4.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P163732
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.68 ± 0.45
Basal Forebrain6.54 ± 0.14
Basal Part of Pons6.56 ± 0.27
Cerebellar Cortex6.72 ± 0.15
Cerebellar Nuclei6.63 ± 0.21
Claustrum6.53 ± 0.5
Epithalamus6.24 ± 0.43
Frontal Lobe6.44 ± 0.32
Globus Pallidus6.08 ± 0.37
Hypothalamus6.36 ± 0.27
Insula6.43 ± 0.19
Limbic Lobe6.48 ± 0.41
Mesencephalon6.52 ± 0.38
Myelencephalon6.47 ± 0.33
Occipital Lobe6.71 ± 0.39
Parietal Lobe6.46 ± 0.23
Pontine Tegmentum6.41 ± 0.35
Striatum6.51 ± 0.42
Subthalamus6.5 ± 0.44
Temporal Lobe6.52 ± 0.28
Thalamus6.56 ± 0.26
White Matter5.23 ± 0.22
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gga2CBCerebellum23.04
22.56
Gga2CTXCerebral cortex81.93
57.05
Gga2HIPHippocampal region48.13
68.07
Gga2HPFHippocampal formation53.49
61.14
Gga2HYHypothalamus44.52
32.94
Gga2LSXLateral septal complex19.23
12.99
Gga2MBMidbrain33.94
26.61
Gga2MYMedulla44.27
42.15
Gga2OLFOlfactory bulb63.03
50.03
Gga2PPons37.09
33
Gga2PALPallidum46.2
36.36
Gga2RHPRetrohippocampal region66.21
48.94
Gga2sAMYStriatum-like amygdalar nuclei59.92
40.22
Gga2STRStriatum53.77
35.29
Gga2STRdStriatum dorsal region56
36.7
Gga2STRvStriatum ventral region58.84
37.51
Gga2THThalamus26.65
21.95
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00500722 18 254 271 RPGQAPPDQEALQVVYER Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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