AutismKB 2.0

Annotation Detail for CAND2


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Basic Information Top
Gene Symbol:CAND2 ( KIAA0667,TIP120B,Tp120b )
Gene Full Name: cullin-associated and neddylation-dissociated 2 (putative)
Band: 3p25.2
Quick LinksEntrez ID:23066; OMIM: 610403; Uniprot ID:CAND2_HUMAN; ENSEMBL ID: ENSG00000144712; HGNC ID: 30689
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus19 / 56401233
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult15 / 19391217
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal56 / 336030716
ovarian tumor4 / 7668252
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma5 / 46356107
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain14 / 110098912
cervix0 / 481710 
connective tissue0 / 1492550 
ear1 / 1621261
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye10 / 21105447
heart2 / 8962622
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver1 / 2077434
lung4 / 33697411
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary5 / 10205148
pancreas1 / 2148124
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis11 / 33044233
thymus0 / 811310 
thyroid4 / 4747384
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213547_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.95
Adipocyte4.95
AdrenalCortex5.85
Adrenalgland4.55
Amygdala14.5
Appendix5.45
AtrioventricularNode5
BDCA4+_DentriticCells5.2
Bonemarrow5.3
BronchialEpithelialCells4.9
CD105+_Endothelial5.1
CD14+_Monocytes4.9
CD19+_BCells(neg._sel.)5.25
CD33+_Myeloid6.4
CD34+8.5
CD4+_Tcells5.3
CD56+_NKCells5.8
CD71+_EarlyErythroid4.65
CD8+_Tcells5.1
CardiacMyocytes7
Caudatenucleus5.25
Cerebellum4.6
CerebellumPeduncles6.15
CiliaryGanglion3.9
CingulateCortex17.5
Colorectaladenocarcinoma5.15
DorsalRootGanglion4.25
FetalThyroid5.65
Fetalbrain18.05
Fetalliver4.5
Fetallung4
GlobusPallidus4.15
Heart223.25
Hypothalamus19.7
Kidney4.4
Leukemia_chronicMyelogenousK-5625.05
Leukemia_promyelocytic-HL-604.5
Leukemialymphoblastic(MOLT-4)4.25
Liver7.25
Lung5.65
Lymphnode4.3
Lymphoma_burkitts(Daudi)6.75
Lymphoma_burkitts(Raji)7.7
MedullaOblongata8
OccipitalLobe7.35
OlfactoryBulb4.9
Ovary3.6
Pancreas4.4
PancreaticIslet6.9
ParietalLobe7.05
Pituitary12.8
Placenta4.9
Pons9.1
PrefrontalCortex27.75
Prostate6.65
Salivarygland4.2
SkeletalMuscle53.65
Skin4.25
SmoothMuscle5.7
Spinalcord6.15
SubthalamicNucleus7.1
SuperiorCervicalGanglion6.4
TemporalLobe5.1
Testis48.05
TestisGermCell36.4
TestisIntersitial18.25
TestisLeydigCell6.85
TestisSeminiferousTubule16.35
Thalamus9.55
Thymus4.2
Thyroid8.6
Tongue8
Tonsil5
Trachea4.45
TrigeminalGanglion6.95
Uterus4.6
UterusCorpus4.95
WholeBlood5.55
Wholebrain25.65
colon5.75
pineal_day65.64
pineal_night51.92
retina35.475
small_intestine5.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P250102
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.07 ± 0.11
Basal Forebrain8.27 ± 0.2
Basal Part of Pons8.02 ± 0.21
Cerebellar Cortex8.05 ± 0.21
Cerebellar Nuclei7.98 ± 0.36
Claustrum8.17 ± 0.32
Epithalamus7.66 ± 0.39
Frontal Lobe8.21 ± 0.27
Globus Pallidus7.55 ± 0.37
Hypothalamus8.17 ± 0.4
Insula8.36 ± 0.24
Limbic Lobe8.07 ± 0.32
Mesencephalon8.06 ± 0.47
Myelencephalon8.03 ± 0.36
Occipital Lobe8.09 ± 0.31
Parietal Lobe8.17 ± 0.29
Pontine Tegmentum8.15 ± 0.39
Striatum7.67 ± 0.42
Subthalamus8.22 ± 0.04
Temporal Lobe8.22 ± 0.27
Thalamus8.13 ± 0.27
White Matter7.56 ± 0.44
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CAND2_HUMAN_953 8 953 960 EVEMGPFK PRIDE
PAp00075262 10 61 70 NGEVQNLAVK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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