AutismKB 2.0

Annotation Detail for PPRC1


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Basic Information Top
Gene Symbol:PPRC1 ( KIAA0595,MGC74642,PRC,RP11-302K17.6 )
Gene Full Name: peroxisome proliferator-activated receptor gamma, coactivator-related 1
Band: 10q24.32
Quick LinksEntrez ID:23082; OMIM: NA; Uniprot ID:PPRC1_HUMAN; ENSEMBL ID: ENSG00000148840; HGNC ID: 30025
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst8 / 62319128
fetus16 / 56401228
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult109 / 193912156
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor13 / 114246113
esophageal tumor0 / 172900 
gastrointestinal tumor18 / 119369150
germ cell tumor11 / 26384541
glioma12 / 106883112
head and neck tumor13 / 13630295
kidney tumor1 / 6895914
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor8 / 10312777
lymphoma6 / 7175583
non-neoplasia3 / 9725030
normal122 / 336030736
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS12 / 12568095
prostate cancer3 / 10268029
retinoblastoma3 / 4635664
skin tumor11 / 12494988
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone2 / 7165527
bone marrow0 / 488010 
brain46 / 110098941
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue17 / 21572278
esophagus0 / 202090 
eye11 / 21105452
heart3 / 8962633
intestine17 / 23447272
kidney1 / 2117774
larynx9 / 24145372
liver3 / 20774314
lung16 / 33697447
lymph5 / 44270112
lymph node9 / 9161098
mammary gland4 / 15327126
mouth3 / 6705244
muscle3 / 10771527
nerve0 / 157680 
ovary4 / 10205139
pancreas10 / 21481246
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta11 / 28082539
prostate8 / 18934542
salivary gland0 / 201550 
skin15 / 21057471
spleen0 / 539520 
stomach21 / 96619217
testis3 / 3304429
thymus1 / 8113112
thyroid9 / 47473189
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203737_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts134.9
Adipocyte19.25
AdrenalCortex21.75
Adrenalgland17.1
Amygdala20.05
Appendix20.05
AtrioventricularNode16.2
BDCA4+_DentriticCells33.4
Bonemarrow20.3
BronchialEpithelialCells19.1
CD105+_Endothelial203.8
CD14+_Monocytes29.35
CD19+_BCells(neg._sel.)21.3
CD33+_Myeloid71
CD34+162.95
CD4+_Tcells26.2
CD56+_NKCells42
CD71+_EarlyErythroid18.55
CD8+_Tcells35.75
CardiacMyocytes27.25
Caudatenucleus17.6
Cerebellum16
CerebellumPeduncles22.25
CiliaryGanglion14.7
CingulateCortex20
Colorectaladenocarcinoma27.65
DorsalRootGanglion15.8
FetalThyroid19.15
Fetalbrain19.15
Fetalliver17.5
Fetallung15.6
GlobusPallidus14.85
Heart26.95
Hypothalamus20.65
Kidney15.95
Leukemia_chronicMyelogenousK-56217.95
Leukemia_promyelocytic-HL-6039.3
Leukemialymphoblastic(MOLT-4)21.45
Liver26.45
Lung22.15
Lymphnode16.55
Lymphoma_burkitts(Daudi)63.8
Lymphoma_burkitts(Raji)41.5
MedullaOblongata17.25
OccipitalLobe17.3
OlfactoryBulb15.4
Ovary13.4
Pancreas16.35
PancreaticIslet21.4
ParietalLobe21.4
Pituitary19.95
Placenta23.7
Pons18.85
PrefrontalCortex23.05
Prostate23.3
Salivarygland13.55
SkeletalMuscle26.25
Skin15.85
SmoothMuscle29.45
Spinalcord20.45
SubthalamicNucleus18.1
SuperiorCervicalGanglion23.75
TemporalLobe17.95
Testis16.85
TestisGermCell16.25
TestisIntersitial16.35
TestisLeydigCell19.45
TestisSeminiferousTubule16.75
Thalamus20.15
Thymus15.75
Thyroid24.15
Tongue20.05
Tonsil19.3
Trachea16.35
TrigeminalGanglion20.65
Uterus15.8
UterusCorpus18.1
WholeBlood19.1
Wholebrain16
colon19.7
pineal_day24.34
pineal_night24
retina23.8
small_intestine19.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12863_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.09 ± 0.59
Basal Forebrain5.39 ± 0.14
Basal Part of Pons5.28 ± 0.43
Cerebellar Cortex5.59 ± 0.36
Cerebellar Nuclei5.08 ± 0.31
Claustrum5.07 ± 0.88
Epithalamus4.99 ± 0.67
Frontal Lobe5.41 ± 0.48
Globus Pallidus4.96 ± 0.36
Hypothalamus5.54 ± 0.4
Insula5.46 ± 0.34
Limbic Lobe5.22 ± 0.48
Mesencephalon5.29 ± 0.54
Myelencephalon5.22 ± 0.53
Occipital Lobe4.99 ± 0.41
Parietal Lobe5.27 ± 0.37
Pontine Tegmentum5.31 ± 0.45
Striatum4.89 ± 0.39
Subthalamus5.4 ± 0.67
Temporal Lobe5.41 ± 0.4
Thalamus5.25 ± 0.52
White Matter5.61 ± 0.21
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pprc1CBCerebellum9.06
15.19
Pprc1CTXCerebral cortex54.92
46.03
Pprc1HIPHippocampal region39.66
64
Pprc1HPFHippocampal formation34.74
46.49
Pprc1HYHypothalamus23.93
20.43
Pprc1LSXLateral septal complex42.11
34.7
Pprc1MBMidbrain13.19
14.86
Pprc1MYMedulla2.21
2.99
Pprc1OLFOlfactory bulb30.11
27.54
Pprc1PPons4.81
6.55
Pprc1PALPallidum15.11
12.97
Pprc1RHPRetrohippocampal region27.07
24.94
Pprc1sAMYStriatum-like amygdalar nuclei9.72
6.35
Pprc1STRStriatum13.84
10.31
Pprc1STRdStriatum dorsal region8.54
6.3
Pprc1STRvStriatum ventral region20.76
14.11
Pprc1THThalamus30.83
26.32
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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