AutismKB 2.0

Annotation Detail for TRIM35


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Basic Information Top
Gene Symbol:TRIM35 ( HLS5,KIAA1098,MAIR,MGC17233 )
Gene Full Name: tripartite motif-containing 35
Band: 8p21.2
Quick LinksEntrez ID:23087; OMIM: NA; Uniprot ID:TRI35_HUMAN; ENSEMBL ID: ENSG00000104228; HGNC ID: 16285
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus13 / 56401223
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult31 / 193912115
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma2 / 7175527
non-neoplasia3 / 9725030
normal44 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain11 / 11009899
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine2 / 2344728
kidney5 / 21177723
larynx0 / 241450 
liver1 / 2077434
lung8 / 33697423
lymph2 / 4427045
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas7 / 21481232
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland1 / 2015549
skin3 / 21057414
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus1 / 8113112
thyroid1 / 4747321
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus11 / 23287847
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P12651
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.2 ± 0.61
Basal Forebrain6.12 ± 0.54
Basal Part of Pons6.66 ± 0.39
Cerebellar Cortex5.91 ± 0.6
Cerebellar Nuclei6.45 ± 0.39
Claustrum6.29 ± 0.56
Epithalamus5.53 ± 0.58
Frontal Lobe6.45 ± 0.81
Globus Pallidus6.86 ± 0.75
Hypothalamus5.76 ± 0.59
Insula6.38 ± 0.77
Limbic Lobe6.55 ± 0.74
Mesencephalon6.09 ± 0.62
Myelencephalon6.38 ± 0.78
Occipital Lobe6.31 ± 0.74
Parietal Lobe6.23 ± 0.67
Pontine Tegmentum6.2 ± 0.77
Striatum6.56 ± 0.74
Subthalamus6.01 ± 0.39
Temporal Lobe6.3 ± 0.81
Thalamus6.39 ± 0.54
White Matter6.67 ± 0.63
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Trim35CBCerebellum45.03
83.08
Trim35CTXCerebral cortex100
100
Trim35HIPHippocampal region100
100
Trim35HPFHippocampal formation100
100
Trim35HYHypothalamus62.65
57.92
Trim35LSXLateral septal complex72.21
60.59
Trim35MBMidbrain68.09
67
Trim35MYMedulla75.43
91.1
Trim35OLFOlfactory bulb100
100
Trim35PPons63.13
71.97
Trim35PALPallidum73.49
81.14
Trim35RHPRetrohippocampal region100
100
Trim35sAMYStriatum-like amygdalar nuclei100
100
Trim35STRStriatum100
100
Trim35STRdStriatum dorsal region100
100
Trim35STRvStriatum ventral region100
85.95
Trim35THThalamus89.26
90.29
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018