AutismKB 2.0

Annotation Detail for ZNF423


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Basic Information Top
Gene Symbol:ZNF423 ( Ebfaz,KIAA0760,MGC138520,MGC138522,OAZ,Roaz,ZFP423,Zfp104 )
Gene Full Name: zinc finger protein 423
Band: 16q12.1
Quick LinksEntrez ID:23090; OMIM: 604557; Uniprot ID:ZN423_HUMAN; ENSEMBL ID: ENSG00000102935; HGNC ID: 16762
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst4 / 6231964
fetus13 / 56401223
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult33 / 193912117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor11 / 26384541
glioma4 / 10688337
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal42 / 336030712
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain25 / 110098922
cervix0 / 481710 
connective tissue11 / 14925573
ear2 / 16212123
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis22 / 33044266
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214761_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.7
Adipocyte4.65
AdrenalCortex5.4
Adrenalgland4.2
Amygdala44.25
Appendix5.35
AtrioventricularNode4.2
BDCA4+_DentriticCells4.55
Bonemarrow5.15
BronchialEpithelialCells4.7
CD105+_Endothelial5.1
CD14+_Monocytes4.9
CD19+_BCells(neg._sel.)4.85
CD33+_Myeloid5.95
CD34+6.1
CD4+_Tcells4.7
CD56+_NKCells5.3
CD71+_EarlyErythroid4.7
CD8+_Tcells4.4
CardiacMyocytes6.95
Caudatenucleus6.8
Cerebellum53.25
CerebellumPeduncles19.35
CiliaryGanglion6.65
CingulateCortex5.85
Colorectaladenocarcinoma4.95
DorsalRootGanglion4.1
FetalThyroid4.75
Fetalbrain8.6
Fetalliver4.5
Fetallung4
GlobusPallidus5.3
Heart7.6
Hypothalamus38.15
Kidney4.15
Leukemia_chronicMyelogenousK-5624.2
Leukemia_promyelocytic-HL-604.05
Leukemialymphoblastic(MOLT-4)3.55
Liver7.05
Lung10.4
Lymphnode4.2
Lymphoma_burkitts(Daudi)5.95
Lymphoma_burkitts(Raji)6.95
MedullaOblongata7.15
OccipitalLobe9.05
OlfactoryBulb4.25
Ovary3.55
Pancreas3.9
PancreaticIslet5.15
ParietalLobe5.65
Pituitary6.1
Placenta5.7
Pons5.05
PrefrontalCortex26.75
Prostate12.75
Salivarygland4.2
SkeletalMuscle6.2
Skin4.15
SmoothMuscle5.6
Spinalcord22.45
SubthalamicNucleus7.6
SuperiorCervicalGanglion6.15
TemporalLobe5.65
Testis7.25
TestisGermCell4.2
TestisIntersitial4.4
TestisLeydigCell5.15
TestisSeminiferousTubule4
Thalamus30.45
Thymus6.65
Thyroid11.35
Tongue5
Tonsil4.6
Trachea4.35
TrigeminalGanglion6.35
Uterus17.3
UterusCorpus4.65
WholeBlood4.95
Wholebrain24.2
colon15
pineal_day747.62
pineal_night853.12
retina77.375
small_intestine16.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15189_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.27 ± 0.89
Basal Forebrain7.43 ± 0.62
Basal Part of Pons7.06 ± 0.94
Cerebellar Cortex7.3 ± 0.57
Cerebellar Nuclei7.2 ± 0.65
Claustrum7.73 ± 1.05
Epithalamus6.87 ± 0.56
Frontal Lobe6.77 ± 0.75
Globus Pallidus8.53 ± 0.4
Hypothalamus6.7 ± 0.65
Insula6.73 ± 0.56
Limbic Lobe6.97 ± 0.98
Mesencephalon7.36 ± 0.66
Myelencephalon7.21 ± 0.66
Occipital Lobe7.62 ± 0.84
Parietal Lobe7.07 ± 0.71
Pontine Tegmentum6.9 ± 0.76
Striatum6.99 ± 0.89
Subthalamus7.02 ± 0.58
Temporal Lobe6.76 ± 0.83
Thalamus7.77 ± 0.58
White Matter8.01 ± 0.71
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfp423CBCerebellum3.09
2.63
Zfp423CTXCerebral cortex0.5
0.44
Zfp423HIPHippocampal region0.92
0.84
Zfp423HPFHippocampal formation0.94
0.75
Zfp423HYHypothalamus0.97
0.56
Zfp423LSXLateral septal complex4.66
2.42
Zfp423MBMidbrain1.89
1.56
Zfp423MYMedulla2.25
1.83
Zfp423OLFOlfactory bulb1.72
1.1
Zfp423PPons2.23
1.7
Zfp423PALPallidum0.72
0.47
Zfp423RHPRetrohippocampal region0.96
0.62
Zfp423sAMYStriatum-like amygdalar nuclei1.17
0.57
Zfp423STRStriatum0.78
0.48
Zfp423STRdStriatum dorsal region0.28
0.26
Zfp423STRvStriatum ventral region0.47
0.31
Zfp423THThalamus5.86
3.47
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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