AutismKB 2.0

Annotation Detail for ARHGAP26


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Basic Information Top
Gene Symbol:ARHGAP26 ( FLJ42530,GRAF,KIAA0621,OPHN1L,OPHN1L1 )
Gene Full Name: Rho GTPase activating protein 26
Band: 5q31.3
Quick LinksEntrez ID:23092; OMIM: 605370; Uniprot ID:RHG26_HUMAN; ENSEMBL ID: ENSG00000145819; HGNC ID: 17073
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus31 / 56401254
neonate1 / 3109732
infant1 / 2362042
juvenile3 / 5555653
adult135 / 193912169
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor11 / 11424696
esophageal tumor1 / 1729057
gastrointestinal tumor16 / 119369134
germ cell tumor7 / 26384526
glioma0 / 1068830 
head and neck tumor23 / 136302168
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma4 / 7175555
non-neoplasia0 / 972500 
normal165 / 336030749
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer6 / 10268058
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor11 / 12519187
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder1 / 2975733
blood5 / 12347840
bone1 / 7165513
bone marrow0 / 488010 
brain44 / 110098939
cervix0 / 481710 
connective tissue11 / 14925573
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus1 / 2020949
eye7 / 21105433
heart8 / 8962689
intestine16 / 23447268
kidney4 / 21177718
larynx1 / 2414541
liver3 / 20774314
lung11 / 33697432
lymph0 / 442700 
lymph node3 / 9161032
mammary gland4 / 15327126
mouth21 / 67052313
muscle8 / 10771574
nerve3 / 15768190
ovary0 / 1020510 
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta22 / 28082578
prostate12 / 18934563
salivary gland0 / 201550 
skin6 / 21057428
spleen2 / 5395237
stomach14 / 96619144
testis6 / 33044218
thymus4 / 8113149
thyroid4 / 4747384
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus8 / 23287834
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215955_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.25
Adipocyte3.25
AdrenalCortex3.4
Adrenalgland2.75
Amygdala3.5
Appendix3.3
AtrioventricularNode2.5
BDCA4+_DentriticCells3.9
Bonemarrow3.25
BronchialEpithelialCells3.25
CD105+_Endothelial3.35
CD14+_Monocytes4.25
CD19+_BCells(neg._sel.)3.5
CD33+_Myeloid4.3
CD34+4.2
CD4+_Tcells3.6
CD56+_NKCells4.05
CD71+_EarlyErythroid3.1
CD8+_Tcells3.25
CardiacMyocytes4.35
Caudatenucleus2.95
Cerebellum2.65
CerebellumPeduncles3.7
CiliaryGanglion2.35
CingulateCortex3.35
Colorectaladenocarcinoma3.3
DorsalRootGanglion2.5
FetalThyroid3.2
Fetalbrain3.25
Fetalliver2.8
Fetallung2.75
GlobusPallidus2.4
Heart4.15
Hypothalamus3.65
Kidney2.65
Leukemia_chronicMyelogenousK-5622.95
Leukemia_promyelocytic-HL-602.9
Leukemialymphoblastic(MOLT-4)2.65
Liver4.3
Lung3.65
Lymphnode2.85
Lymphoma_burkitts(Daudi)4.2
Lymphoma_burkitts(Raji)4.6
MedullaOblongata3
OccipitalLobe3
OlfactoryBulb2.6
Ovary2.2
Pancreas2.65
PancreaticIslet3.5
ParietalLobe3.45
Pituitary3.8
Placenta3.45
Pons3.1
PrefrontalCortex4.15
Prostate3.85
Salivarygland2.6
SkeletalMuscle3.75
Skin2.55
SmoothMuscle3.7
Spinalcord3.5
SubthalamicNucleus2.95
SuperiorCervicalGanglion3.7
TemporalLobe3
Testis2.85
TestisGermCell2.8
TestisIntersitial2.75
TestisLeydigCell3.25
TestisSeminiferousTubule2.8
Thalamus3.35
Thymus2.6
Thyroid4.15
Tongue3.15
Tonsil3.2
Trachea2.75
TrigeminalGanglion3.25
Uterus2.75
UterusCorpus2.95
WholeBlood4
Wholebrain2.8
colon3.3
pineal_day4.14
pineal_night4.04
retina4
small_intestine3.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P214066
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.74 ± 0.39
Basal Forebrain8.14 ± 0.25
Basal Part of Pons7.66 ± 0.25
Cerebellar Cortex8.64 ± 0.16
Cerebellar Nuclei7.72 ± 0.33
Claustrum8.43 ± 0.26
Epithalamus7.66 ± 0.37
Frontal Lobe8.38 ± 0.49
Globus Pallidus7.02 ± 0.4
Hypothalamus8.1 ± 0.39
Insula8.21 ± 0.35
Limbic Lobe8.62 ± 0.46
Mesencephalon8.22 ± 0.45
Myelencephalon8.34 ± 0.45
Occipital Lobe8.82 ± 0.33
Parietal Lobe8.51 ± 0.41
Pontine Tegmentum8.35 ± 0.39
Striatum7.78 ± 0.5
Subthalamus8.02 ± 0.32
Temporal Lobe8.38 ± 0.34
Thalamus7.92 ± 0.36
White Matter6.44 ± 0.42
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Arhgap26CBCerebellum25.58
91.23
Arhgap26CTXCerebral cortex59.98
27.8
Arhgap26HIPHippocampal region13.96
10.03
Arhgap26HPFHippocampal formation30.81
16.79
Arhgap26HYHypothalamus9.06
3.06
Arhgap26LSXLateral septal complex10.74
3.57
Arhgap26MBMidbrain5.9
2.82
Arhgap26MYMedulla6.83
4.66
Arhgap26OLFOlfactory bulb30.16
12.11
Arhgap26PPons6.36
4.24
Arhgap26PALPallidum11.91
5.1
Arhgap26RHPRetrohippocampal region51.01
23.13
Arhgap26sAMYStriatum-like amygdalar nuclei33.57
12.29
Arhgap26STRStriatum10.13
3.62
Arhgap26STRdStriatum dorsal region5.77
2.37
Arhgap26STRvStriatum ventral region11.45
3.09
Arhgap26THThalamus4.96
3.33
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp01434935 10 486 495 VSEIHSLVHR Peptide Atlas
RHG26_HUMAN_48 11 48 58 SALKNLSSAKR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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