AutismKB 2.0

Annotation Detail for SIPA1L3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SIPA1L3 ( SPAL3 )
Gene Full Name: signal-induced proliferation-associated 1 like 3
Band: 19q13.13-q13.2
Quick LinksEntrez ID:23094; OMIM: NA; Uniprot ID:SI1L3_HUMAN; ENSEMBL ID: ENSG00000105738; HGNC ID: 23801
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult65 / 193912133
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma2 / 17475114
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor2 / 2638457
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia13 / 95842135
liver tumor3 / 9635931
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal74 / 336030722
ovarian tumor3 / 7668239
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood4 / 12347832
bone0 / 716550 
bone marrow0 / 488010 
brain6 / 11009895
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye6 / 21105428
heart1 / 8962611
intestine13 / 23447255
kidney0 / 2117770 
larynx1 / 2414541
liver4 / 20774319
lung3 / 3369748
lymph1 / 4427022
lymph node22 / 91610240
mammary gland2 / 15327113
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary3 / 10205129
pancreas9 / 21481241
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate4 / 18934521
salivary gland0 / 201550 
skin1 / 2105744
spleen2 / 5395237
stomach4 / 9661941
testis5 / 33044215
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 37831_at
Cell line Expression level Expression bar
721_B_lymphoblasts35
Adipocyte22.4
AdrenalCortex29.25
Adrenalgland23
Amygdala27.9
Appendix29.15
AtrioventricularNode21.1
BDCA4+_DentriticCells40.8
Bonemarrow29.8
BronchialEpithelialCells24.4
CD105+_Endothelial23.65
CD14+_Monocytes30.05
CD19+_BCells(neg._sel.)46.1
CD33+_Myeloid35.35
CD34+30.95
CD4+_Tcells20.55
CD56+_NKCells27.15
CD71+_EarlyErythroid23.1
CD8+_Tcells23
CardiacMyocytes31.4
Caudatenucleus24.85
Cerebellum42.45
CerebellumPeduncles39.1
CiliaryGanglion23.6
CingulateCortex33.35
Colorectaladenocarcinoma27.1
DorsalRootGanglion24.45
FetalThyroid36.35
Fetalbrain40.15
Fetalliver21.5
Fetallung22.95
GlobusPallidus28.15
Heart34.25
Hypothalamus29.15
Kidney44.7
Leukemia_chronicMyelogenousK-56224.95
Leukemia_promyelocytic-HL-6036.25
Leukemialymphoblastic(MOLT-4)22.45
Liver39.45
Lung39.6
Lymphnode32.45
Lymphoma_burkitts(Daudi)39
Lymphoma_burkitts(Raji)38.85
MedullaOblongata22.05
OccipitalLobe24.25
OlfactoryBulb21.7
Ovary19
Pancreas29.85
PancreaticIslet47.45
ParietalLobe31.85
Pituitary39.05
Placenta25.4
Pons29.8
PrefrontalCortex27.8
Prostate28.95
Salivarygland28.3
SkeletalMuscle35.3
Skin29.8
SmoothMuscle33.55
Spinalcord30.25
SubthalamicNucleus29.8
SuperiorCervicalGanglion29.5
TemporalLobe25.1
Testis24.55
TestisGermCell23.4
TestisIntersitial21.55
TestisLeydigCell27.4
TestisSeminiferousTubule23.7
Thalamus28.75
Thymus22.25
Thyroid32.35
Tongue32.55
Tonsil31.9
Trachea23.55
TrigeminalGanglion26.7
Uterus16.5
UterusCorpus28.25
WholeBlood23.3
Wholebrain20.2
colon25.7
pineal_day28.74
pineal_night28.08
retina31.675
small_intestine25.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P24343
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.18 ± 0.96
Basal Forebrain1.71 ± 0.19
Basal Part of Pons1.53 ± 0.41
Cerebellar Cortex1.79 ± 0.76
Cerebellar Nuclei2.07 ± 0.71
Claustrum2.7 ± 0.86
Epithalamus1.46 ± 0.69
Frontal Lobe1.67 ± 0.7
Globus Pallidus2.33 ± 0.31
Hypothalamus1.85 ± 0.61
Insula1.66 ± 0.51
Limbic Lobe1.85 ± 0.61
Mesencephalon1.94 ± 0.68
Myelencephalon1.83 ± 0.65
Occipital Lobe1.81 ± 0.55
Parietal Lobe1.73 ± 0.58
Pontine Tegmentum1.84 ± 0.64
Striatum1.87 ± 0.49
Subthalamus2.02 ± 0.67
Temporal Lobe1.67 ± 0.59
Thalamus1.74 ± 0.59
White Matter2.25 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
2610511M17RikCBCerebellum7.25
7.8
2610511M17RikCTXCerebral cortex3.82
4.73
2610511M17RikHIPHippocampal region49.72
98.32
2610511M17RikHPFHippocampal formation35.77
63.8
2610511M17RikHYHypothalamus1.15
1.01
2610511M17RikLSXLateral septal complex1.36
1.04
2610511M17RikMBMidbrain1.58
1.74
2610511M17RikMYMedulla5.13
5.96
2610511M17RikOLFOlfactory bulb3.08
3.44
2610511M17RikPPons3.52
4.15
2610511M17RikPALPallidum0.73
0.64
2610511M17RikRHPRetrohippocampal region6.39
6.05
2610511M17RiksAMYStriatum-like amygdalar nuclei1.44
1.18
2610511M17RikSTRStriatum6.8
4.82
2610511M17RikSTRdStriatum dorsal region9.73
7.04
2610511M17RikSTRvStriatum ventral region3.72
2.35
2610511M17RikTHThalamus4.26
7.81
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00095557 17 827 843 DLAENCVSNTPIDSTGK Peptide Atlas
SI1L3_HUMAN_1104 13 1104 1116 LIIMDNLGPEQER PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved