AutismKB 2.0

Annotation Detail for CDK19


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Basic Information Top
Gene Symbol:CDK19 ( CDC2L6,CDK11,KIAA1028,bA346C16.3 )
Gene Full Name: cyclin-dependent kinase 19
Band: 6q21
Quick LinksEntrez ID:23097; OMIM: NA; Uniprot ID:CDK19_HUMAN; ENSEMBL ID: ENSG00000155111; HGNC ID: 19338
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst1 / 6231916
fetus40 / 56401270
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult50 / 193912125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor4 / 11424635
esophageal tumor1 / 1729057
gastrointestinal tumor3 / 11936925
germ cell tumor6 / 26384522
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal141 / 336030741
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone5 / 7165569
bone marrow0 / 488010 
brain23 / 110098920
cervix0 / 481710 
connective tissue3 / 14925520
ear1 / 1621261
embryonic tissue8 / 21572237
esophagus1 / 2020949
eye8 / 21105437
heart2 / 8962622
intestine5 / 23447221
kidney3 / 21177714
larynx0 / 241450 
liver2 / 2077439
lung13 / 33697438
lymph1 / 4427022
lymph node6 / 9161065
mammary gland4 / 15327126
mouth0 / 670520 
muscle2 / 10771518
nerve2 / 15768126
ovary1 / 1020519
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate15 / 18934579
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach4 / 9661941
testis32 / 33044296
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus11 / 23287847
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212897_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.65
Adipocyte5.5
AdrenalCortex5.7
Adrenalgland4.85
Amygdala5.55
Appendix6.35
AtrioventricularNode4.65
BDCA4+_DentriticCells6.35
Bonemarrow5.85
BronchialEpithelialCells4.5
CD105+_Endothelial5.8
CD14+_Monocytes6.1
CD19+_BCells(neg._sel.)6.15
CD33+_Myeloid11.7
CD34+9.5
CD4+_Tcells5.55
CD56+_NKCells6.75
CD71+_EarlyErythroid5.55
CD8+_Tcells5.2
CardiacMyocytes5.35
Caudatenucleus7.15
Cerebellum4.6
CerebellumPeduncles6.5
CiliaryGanglion4.95
CingulateCortex7.3
Colorectaladenocarcinoma5.55
DorsalRootGanglion4.75
FetalThyroid5.15
Fetalbrain12.35
Fetalliver5
Fetallung4.55
GlobusPallidus6.9
Heart7
Hypothalamus7
Kidney4.5
Leukemia_chronicMyelogenousK-5625.1
Leukemia_promyelocytic-HL-604.9
Leukemialymphoblastic(MOLT-4)5.3
Liver6.7
Lung6.05
Lymphnode4.75
Lymphoma_burkitts(Daudi)7.35
Lymphoma_burkitts(Raji)7.85
MedullaOblongata9.7
OccipitalLobe6.5
OlfactoryBulb6.85
Ovary3.95
Pancreas4.45
PancreaticIslet6.1
ParietalLobe6.25
Pituitary6.6
Placenta6.25
Pons6.5
PrefrontalCortex25
Prostate8.05
Salivarygland4.55
SkeletalMuscle6.85
Skin4.95
SmoothMuscle6.15
Spinalcord8.2
SubthalamicNucleus5.7
SuperiorCervicalGanglion7.15
TemporalLobe6.1
Testis4.9
TestisGermCell4.8
TestisIntersitial4.75
TestisLeydigCell5.7
TestisSeminiferousTubule4.85
Thalamus5.65
Thymus4.55
Thyroid6.4
Tongue6
Tonsil5.5
Trachea4.65
TrigeminalGanglion5.95
Uterus4.6
UterusCorpus5
WholeBlood6.2
Wholebrain4.65
colon5.45
pineal_day6.98
pineal_night6.48
retina6.825
small_intestine4.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10208_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.35 ± 0.36
Basal Forebrain6.86 ± 0.23
Basal Part of Pons6.35 ± 0.52
Cerebellar Cortex6.44 ± 0.24
Cerebellar Nuclei6.49 ± 0.43
Claustrum6.18 ± 0.46
Epithalamus6.1 ± 0.6
Frontal Lobe6.2 ± 0.44
Globus Pallidus7.22 ± 0.26
Hypothalamus5.76 ± 0.45
Insula6.14 ± 0.22
Limbic Lobe6.35 ± 0.41
Mesencephalon6.45 ± 0.58
Myelencephalon6.43 ± 0.51
Occipital Lobe6.89 ± 0.33
Parietal Lobe6.51 ± 0.42
Pontine Tegmentum6.51 ± 0.44
Striatum6.91 ± 0.55
Subthalamus6.36 ± 0.32
Temporal Lobe6.42 ± 0.34
Thalamus6.48 ± 0.42
White Matter8.39 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cdc2l6CBCerebellum10.17
9.61
Cdc2l6CTXCerebral cortex26.55
18.19
Cdc2l6HIPHippocampal region11.04
9.43
Cdc2l6HPFHippocampal formation10.37
8.17
Cdc2l6HYHypothalamus4.91
3.25
Cdc2l6LSXLateral septal complex5.92
4.35
Cdc2l6MBMidbrain5.19
4.18
Cdc2l6MYMedulla12.64
11.02
Cdc2l6OLFOlfactory bulb28.23
21.46
Cdc2l6PPons11.05
9.8
Cdc2l6PALPallidum8.62
6.52
Cdc2l6RHPRetrohippocampal region9.25
6.27
Cdc2l6sAMYStriatum-like amygdalar nuclei12.72
8.98
Cdc2l6STRStriatum32.28
23.46
Cdc2l6STRdStriatum dorsal region39.37
28.99
Cdc2l6STRvStriatum ventral region31.39
21.98
Cdc2l6THThalamus11.86
9.55
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00010005 13 14 26 ERVEDLFEYEGCK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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