AutismKB 2.0

Annotation Detail for FSTL4


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Basic Information Top
Gene Symbol:FSTL4 ( - )
Gene Full Name: follistatin-like 4
Band: 5q31.1
Quick LinksEntrez ID:23105; OMIM: NA; Uniprot ID:FSTL4_HUMAN; ENSEMBL ID: ENSG00000053108; HGNC ID: 21389
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus5 / 5640128
neonate0 / 310970 
infant3 / 23620127
juvenile0 / 555560 
adult22 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma5 / 17475286
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor5 / 10312748
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal32 / 33603079
ovarian tumor0 / 766820 
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain15 / 110098913
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye7 / 21105433
heart0 / 896260 
intestine0 / 2344720 
kidney3 / 21177714
larynx0 / 241450 
liver0 / 2077430 
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth2 / 6705229
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214859_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.7
Adipocyte5.65
AdrenalCortex6.15
Adrenalgland5.05
Amygdala5.8
Appendix9.2
AtrioventricularNode4.55
BDCA4+_DentriticCells5.75
Bonemarrow5.75
BronchialEpithelialCells5.55
CD105+_Endothelial5.65
CD14+_Monocytes6
CD19+_BCells(neg._sel.)6.05
CD33+_Myeloid7.25
CD34+7.15
CD4+_Tcells6
CD56+_NKCells6.6
CD71+_EarlyErythroid5.35
CD8+_Tcells5.2
CardiacMyocytes7.3
Caudatenucleus5.15
Cerebellum6.25
CerebellumPeduncles6.65
CiliaryGanglion4.3
CingulateCortex5.95
Colorectaladenocarcinoma5.7
DorsalRootGanglion4.65
FetalThyroid5.55
Fetalbrain5.65
Fetalliver5
Fetallung4.5
GlobusPallidus4.2
Heart7.5
Hypothalamus6.2
Kidney4.95
Leukemia_chronicMyelogenousK-5625.2
Leukemia_promyelocytic-HL-605.1
Leukemialymphoblastic(MOLT-4)4.55
Liver7.85
Lung6.2
Lymphnode4.85
Lymphoma_burkitts(Daudi)7.3
Lymphoma_burkitts(Raji)7.55
MedullaOblongata6.55
OccipitalLobe5.1
OlfactoryBulb4.5
Ovary3.95
Pancreas4.6
PancreaticIslet6.1
ParietalLobe6.2
Pituitary6.7
Placenta5.75
Pons5.6
PrefrontalCortex7.05
Prostate6.55
Salivarygland5.35
SkeletalMuscle7.85
Skin4.45
SmoothMuscle6.5
Spinalcord6.1
SubthalamicNucleus5.25
SuperiorCervicalGanglion6.65
TemporalLobe5.7
Testis4.9
TestisGermCell4.7
TestisIntersitial4.7
TestisLeydigCell5.8
TestisSeminiferousTubule4.85
Thalamus5.9
Thymus4.45
Thyroid7.1
Tongue6.55
Tonsil5.55
Trachea4.75
TrigeminalGanglion6.35
Uterus4.55
UterusCorpus5.45
WholeBlood6.2
Wholebrain5.7
colon5.7
pineal_day7.08
pineal_night6.62
retina6.7
small_intestine5.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12776_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.97 ± 0.46
Basal Forebrain7.72 ± 0.66
Basal Part of Pons7.88 ± 0.41
Cerebellar Cortex7.72 ± 0.34
Cerebellar Nuclei7.99 ± 0.38
Claustrum8.87 ± 0.42
Epithalamus6.7 ± 0.95
Frontal Lobe7.56 ± 0.72
Globus Pallidus4.85 ± 0.95
Hypothalamus7.71 ± 0.49
Insula7.41 ± 0.61
Limbic Lobe6.76 ± 0.81
Mesencephalon7.48 ± 0.81
Myelencephalon7.63 ± 0.88
Occipital Lobe8.18 ± 0.55
Parietal Lobe8.08 ± 0.55
Pontine Tegmentum7.96 ± 0.68
Striatum8.04 ± 0.66
Subthalamus7.85 ± 0.47
Temporal Lobe7.8 ± 0.57
Thalamus8.6 ± 0.8
White Matter3.87 ± 0.92
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fstl4CBCerebellum13.27
22.42
Fstl4CTXCerebral cortex24.04
18.93
Fstl4HIPHippocampal region9.17
10.48
Fstl4HPFHippocampal formation8.22
9.05
Fstl4HYHypothalamus1.65
1.37
Fstl4LSXLateral septal complex1.43
1.22
Fstl4MBMidbrain1.7
1.85
Fstl4MYMedulla3.38
3.9
Fstl4OLFOlfactory bulb21.94
21.51
Fstl4PPons1.65
1.76
Fstl4PALPallidum1.65
1.48
Fstl4RHPRetrohippocampal region7.86
8.1
Fstl4sAMYStriatum-like amygdalar nuclei2.58
2.18
Fstl4STRStriatum4.29
3.19
Fstl4STRdStriatum dorsal region3.59
2.57
Fstl4STRvStriatum ventral region9.11
6.51
Fstl4THThalamus11.85
10.49
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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