AutismKB 2.0

Annotation Detail for CUL9


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Basic Information Top
Gene Symbol:CUL9 ( DKFZp686G1042,DKFZp686P2024,H7AP1,PARC,RP3-330M21.2 )
Gene Full Name: cullin 9
Band: 6p21.1
Quick LinksEntrez ID:23113; OMIM: 607489; Uniprot ID:CUL9_HUMAN; ENSEMBL ID: ENSG00000112659; HGNC ID: 15982
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst1 / 6231916
fetus15 / 56401226
neonate5 / 31097160
infant0 / 236200 
juvenile2 / 5555635
adult56 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor6 / 11424652
esophageal tumor1 / 1729057
gastrointestinal tumor2 / 11936916
germ cell tumor4 / 26384515
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor4 / 6895958
leukemia4 / 9584241
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma2 / 7175527
non-neoplasia2 / 9725020
normal99 / 336030729
ovarian tumor2 / 7668226
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain27 / 110098924
cervix2 / 4817141
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus1 / 2020949
eye2 / 2110549
heart1 / 8962611
intestine9 / 23447238
kidney7 / 21177733
larynx0 / 241450 
liver2 / 2077439
lung14 / 33697441
lymph1 / 4427022
lymph node13 / 91610141
mammary gland3 / 15327119
mouth1 / 6705214
muscle4 / 10771537
nerve1 / 1576863
ovary3 / 10205129
pancreas13 / 21481260
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate4 / 18934521
salivary gland0 / 201550 
skin1 / 2105744
spleen1 / 5395218
stomach2 / 9661920
testis12 / 33044236
thymus9 / 81131110
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord5 / 13680365
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213204_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.6
Adipocyte6.5
AdrenalCortex7.85
Adrenalgland6
Amygdala8.3
Appendix7.65
AtrioventricularNode5.75
BDCA4+_DentriticCells13.5
Bonemarrow7.15
BronchialEpithelialCells7.2
CD105+_Endothelial12.05
CD14+_Monocytes8.25
CD19+_BCells(neg._sel.)10.9
CD33+_Myeloid10.1
CD34+11.4
CD4+_Tcells53.1
CD56+_NKCells9.1
CD71+_EarlyErythroid6.55
CD8+_Tcells34.2
CardiacMyocytes11.1
Caudatenucleus6.5
Cerebellum5.75
CerebellumPeduncles8.15
CiliaryGanglion5.05
CingulateCortex8.75
Colorectaladenocarcinoma7.4
DorsalRootGanglion5.5
FetalThyroid15
Fetalbrain7.8
Fetalliver6
Fetallung6.05
GlobusPallidus5.3
Heart10.8
Hypothalamus12.5
Kidney5.95
Leukemia_chronicMyelogenousK-5626.95
Leukemia_promyelocytic-HL-606.35
Leukemialymphoblastic(MOLT-4)9.25
Liver9.6
Lung7.55
Lymphnode8.85
Lymphoma_burkitts(Daudi)9.5
Lymphoma_burkitts(Raji)11.8
MedullaOblongata8.55
OccipitalLobe6.55
OlfactoryBulb5.85
Ovary4.85
Pancreas5.5
PancreaticIslet7.45
ParietalLobe7.45
Pituitary8.6
Placenta6.5
Pons6.95
PrefrontalCortex30.45
Prostate9.05
Salivarygland5.7
SkeletalMuscle8.25
Skin5.55
SmoothMuscle7.95
Spinalcord7.45
SubthalamicNucleus10.1
SuperiorCervicalGanglion8.15
TemporalLobe6.65
Testis27.8
TestisGermCell15.3
TestisIntersitial46.7
TestisLeydigCell7.3
TestisSeminiferousTubule26.85
Thalamus8.15
Thymus7.75
Thyroid16.65
Tongue7.15
Tonsil7.6
Trachea5.75
TrigeminalGanglion7.5
Uterus6.05
UterusCorpus6.5
WholeBlood8.1
Wholebrain11.35
colon6.85
pineal_day20.64
pineal_night9.1
retina11.2
small_intestine6.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9630_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.54 ± 0.78
Basal Forebrain2.94 ± 0.47
Basal Part of Pons3.37 ± 0.84
Cerebellar Cortex3.42 ± 0.71
Cerebellar Nuclei3.28 ± 0.64
Claustrum3.34 ± 0.67
Epithalamus3.6 ± 0.8
Frontal Lobe3.45 ± 0.69
Globus Pallidus2.3 ± 0.61
Hypothalamus3.32 ± 0.32
Insula3.57 ± 0.59
Limbic Lobe3.23 ± 0.63
Mesencephalon3.37 ± 0.65
Myelencephalon3.28 ± 0.6
Occipital Lobe3.04 ± 0.55
Parietal Lobe3.31 ± 0.62
Pontine Tegmentum3.28 ± 0.64
Striatum3.14 ± 0.69
Subthalamus3.45 ± 0.93
Temporal Lobe3.52 ± 0.53
Thalamus3.35 ± 0.62
White Matter2.58 ± 1
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
ParcCBCerebellum11.54
10.78
ParcCTXCerebral cortex24.11
15.69
ParcHIPHippocampal region22.83
27.28
ParcHPFHippocampal formation23.66
23.12
ParcHYHypothalamus3.74
2.48
ParcLSXLateral septal complex3.78
2.06
ParcMBMidbrain9.69
8.29
ParcMYMedulla13.34
12.73
ParcOLFOlfactory bulb19.25
13.06
ParcPPons9.67
8.92
ParcPALPallidum7.56
5.7
ParcRHPRetrohippocampal region24.84
18.29
ParcsAMYStriatum-like amygdalar nuclei7.23
4.71
ParcSTRStriatum7.26
4.67
ParcSTRdStriatum dorsal region7.13
4.68
ParcSTRvStriatum ventral region8.27
4.96
ParcTHThalamus13.77
10.21
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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