AutismKB 2.0

Annotation Detail for CLASP2


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Basic Information Top
Gene Symbol:CLASP2 ( - )
Gene Full Name: cytoplasmic linker associated protein 2
Band: 3p22.3
Quick LinksEntrez ID:23122; OMIM: 605853; Uniprot ID:CLAP2_HUMAN; ENSEMBL ID: ENSG00000163539; HGNC ID: 17078
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst8 / 62319128
fetus135 / 564012239
neonate0 / 310970 
infant1 / 2362042
juvenile2 / 5555635
adult141 / 193912172
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor12 / 94178127
cervical tumor2 / 3436658
chondrosarcoma6 / 8282372
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor13 / 119369108
germ cell tumor20 / 26384575
glioma5 / 10688346
head and neck tumor6 / 13630244
kidney tumor6 / 6895987
leukemia10 / 95842104
liver tumor3 / 9635931
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia10 / 97250102
normal486 / 3360307144
ovarian tumor3 / 7668239
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer1 / 1026809
retinoblastoma2 / 4635643
skin tumor5 / 12494940
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood5 / 12347840
bone5 / 7165569
bone marrow1 / 4880120
brain341 / 1100989309
cervix2 / 4817141
connective tissue8 / 14925553
ear5 / 16212308
embryonic tissue18 / 21572283
esophagus0 / 202090 
eye24 / 211054113
heart6 / 8962666
intestine10 / 23447242
kidney10 / 21177747
larynx1 / 2414541
liver4 / 20774319
lung14 / 33697441
lymph0 / 442700 
lymph node18 / 91610196
mammary gland14 / 15327191
mouth5 / 6705274
muscle7 / 10771564
nerve2 / 15768126
ovary3 / 10205129
pancreas10 / 21481246
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland3 / 16585180
placenta9 / 28082532
prostate6 / 18934531
salivary gland1 / 2015549
skin8 / 21057437
spleen1 / 5395218
stomach13 / 96619134
testis21 / 33044263
thymus5 / 8113161
thyroid0 / 474730 
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus14 / 23287860
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212306_at
Cell line Expression level Expression bar
721_B_lymphoblasts25.9
Adipocyte8.9
AdrenalCortex11.75
Adrenalgland8.4
Amygdala277.65
Appendix11.35
AtrioventricularNode9.35
BDCA4+_DentriticCells57.05
Bonemarrow9.75
BronchialEpithelialCells10.5
CD105+_Endothelial15.85
CD14+_Monocytes14.6
CD19+_BCells(neg._sel.)14.95
CD33+_Myeloid24.95
CD34+17.95
CD4+_Tcells20.25
CD56+_NKCells26
CD71+_EarlyErythroid10.95
CD8+_Tcells24.1
CardiacMyocytes14.3
Caudatenucleus106.7
Cerebellum12.3
CerebellumPeduncles59.85
CiliaryGanglion8.5
CingulateCortex87.15
Colorectaladenocarcinoma9.5
DorsalRootGanglion10.4
FetalThyroid9
Fetalbrain612.15
Fetalliver8.15
Fetallung8.2
GlobusPallidus41.55
Heart15.2
Hypothalamus241.95
Kidney7.95
Leukemia_chronicMyelogenousK-56214.3
Leukemia_promyelocytic-HL-609.85
Leukemialymphoblastic(MOLT-4)11.35
Liver12.15
Lung9.85
Lymphnode8.45
Lymphoma_burkitts(Daudi)17.8
Lymphoma_burkitts(Raji)13.5
MedullaOblongata113.45
OccipitalLobe336.35
OlfactoryBulb42.85
Ovary6.45
Pancreas7.15
PancreaticIslet9.95
ParietalLobe128.05
Pituitary39.2
Placenta8.95
Pons20.95
PrefrontalCortex237.7
Prostate11.2
Salivarygland9.65
SkeletalMuscle14.75
Skin8.6
SmoothMuscle9.9
Spinalcord122.65
SubthalamicNucleus64.8
SuperiorCervicalGanglion14.7
TemporalLobe29.65
Testis6.6
TestisGermCell8.3
TestisIntersitial8.5
TestisLeydigCell8.8
TestisSeminiferousTubule7.75
Thalamus132.7
Thymus7.4
Thyroid12.15
Tongue10.4
Tonsil11.05
Trachea7.8
TrigeminalGanglion12.45
Uterus8.25
UterusCorpus9.05
WholeBlood10.65
Wholebrain19.95
colon11.1
pineal_day500.98
pineal_night491.5
retina104.425
small_intestine10.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P127748
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.02 ± 0.23
Basal Forebrain8.05 ± 0.17
Basal Part of Pons8.48 ± 0.18
Cerebellar Cortex8.41 ± 0.1
Cerebellar Nuclei8.27 ± 0.32
Claustrum8.38 ± 0.26
Epithalamus8.24 ± 0.16
Frontal Lobe8.17 ± 0.25
Globus Pallidus7.93 ± 0.21
Hypothalamus8.12 ± 0.23
Insula8.13 ± 0.29
Limbic Lobe8.2 ± 0.25
Mesencephalon8.19 ± 0.27
Myelencephalon8.16 ± 0.26
Occipital Lobe8.4 ± 0.2
Parietal Lobe8.26 ± 0.23
Pontine Tegmentum8.18 ± 0.2
Striatum7.86 ± 0.23
Subthalamus8.13 ± 0.37
Temporal Lobe8.21 ± 0.22
Thalamus8.25 ± 0.25
White Matter9.08 ± 0.07
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Clasp2CBCerebellum10.87
13.45
Clasp2CTXCerebral cortex29.42
19.48
Clasp2HIPHippocampal region26.23
27.56
Clasp2HPFHippocampal formation26.36
24
Clasp2HYHypothalamus12.19
8.4
Clasp2LSXLateral septal complex11.58
7.45
Clasp2MBMidbrain23.46
19.51
Clasp2MYMedulla29.21
29.64
Clasp2OLFOlfactory bulb27.15
18.58
Clasp2PPons25
24.08
Clasp2PALPallidum14.89
12.4
Clasp2RHPRetrohippocampal region26.93
19.52
Clasp2sAMYStriatum-like amygdalar nuclei11.55
7.9
Clasp2STRStriatum11.22
7.5
Clasp2STRdStriatum dorsal region11.67
7.99
Clasp2STRvStriatum ventral region9.54
5.82
Clasp2THThalamus41.84
33.31
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00006927 24 834 857 RYESYGMHSDDDANSDASSACSER Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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