AutismKB 2.0

Annotation Detail for MAST2


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Basic Information Top
Gene Symbol:MAST2 ( FLJ39200,KIAA0807,MAST205,MTSSK,RP4-533D7.1 )
Gene Full Name: microtubule associated serine/threonine kinase 2
Band: 1p34.1
Quick LinksEntrez ID:23139; OMIM: 612257; Uniprot ID:MAST2_HUMAN; ENSEMBL ID: ENSG00000086015; HGNC ID: 19035
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst4 / 6231964
fetus22 / 56401239
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult86 / 193912144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma2 / 17475114
breast (mammary gland) tumor6 / 9417863
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor10 / 11424687
esophageal tumor0 / 172900 
gastrointestinal tumor11 / 11936992
germ cell tumor14 / 26384553
glioma3 / 10688328
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia4 / 9584241
liver tumor0 / 963590 
lung tumor6 / 10312758
lymphoma7 / 7175597
non-neoplasia3 / 9725030
normal131 / 336030738
ovarian tumor2 / 7668226
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer8 / 10268077
retinoblastoma2 / 4635643
skin tumor10 / 12494980
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland3 / 3319790
ascites2 / 4001549
bladder1 / 2975733
blood1 / 1234788
bone6 / 7165583
bone marrow1 / 4880120
brain19 / 110098917
cervix0 / 481710 
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue14 / 21572264
esophagus0 / 202090 
eye11 / 21105452
heart5 / 8962655
intestine23 / 23447298
kidney3 / 21177714
larynx2 / 2414582
liver1 / 2077434
lung13 / 33697438
lymph4 / 4427090
lymph node29 / 91610316
mammary gland8 / 15327152
mouth0 / 670520 
muscle9 / 10771583
nerve4 / 15768253
ovary3 / 10205129
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta13 / 28082546
prostate8 / 18934542
salivary gland0 / 201550 
skin18 / 21057485
spleen0 / 539520 
stomach3 / 9661931
testis13 / 33044239
thymus3 / 8113136
thyroid2 / 4747342
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus16 / 23287868
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215660_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts12.1
Adipocyte9.35
AdrenalCortex12.25
Adrenalgland9.75
Amygdala9.3
Appendix11.75
AtrioventricularNode7.9
BDCA4+_DentriticCells10.4
Bonemarrow9.1
BronchialEpithelialCells7.85
CD105+_Endothelial9.45
CD14+_Monocytes9.5
CD19+_BCells(neg._sel.)9.55
CD33+_Myeloid12
CD34+12.1
CD4+_Tcells10.25
CD56+_NKCells11.35
CD71+_EarlyErythroid9.35
CD8+_Tcells9.1
CardiacMyocytes11.75
Caudatenucleus8.4
Cerebellum8.3
CerebellumPeduncles10.6
CiliaryGanglion6.7
CingulateCortex10.1
Colorectaladenocarcinoma9.45
DorsalRootGanglion7.05
FetalThyroid9
Fetalbrain9.95
Fetalliver8.55
Fetallung7.75
GlobusPallidus9.45
Heart11.8
Hypothalamus10.45
Kidney7.55
Leukemia_chronicMyelogenousK-5628.4
Leukemia_promyelocytic-HL-608.3
Leukemialymphoblastic(MOLT-4)7.65
Liver12.25
Lung9.25
Lymphnode8.1
Lymphoma_burkitts(Daudi)12.4
Lymphoma_burkitts(Raji)13
MedullaOblongata9.85
OccipitalLobe8.35
OlfactoryBulb7.35
Ovary6.7
Pancreas10.2
PancreaticIslet9.85
ParietalLobe10.2
Pituitary11.1
Placenta10.25
Pons17.75
PrefrontalCortex11.85
Prostate10.4
Salivarygland7.65
SkeletalMuscle22.25
Skin8.25
SmoothMuscle10.65
Spinalcord10.85
SubthalamicNucleus8.5
SuperiorCervicalGanglion10.45
TemporalLobe10.8
Testis9.7
TestisGermCell8.05
TestisIntersitial8.3
TestisLeydigCell9.45
TestisSeminiferousTubule8.35
Thalamus13.55
Thymus6.9
Thyroid10.6
Tongue9.85
Tonsil9.1
Trachea8
TrigeminalGanglion11.75
Uterus6.4
UterusCorpus9.65
WholeBlood9.2
Wholebrain6.7
colon9.45
pineal_day11.74
pineal_night11.24
retina11.5
small_intestine9.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8088_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.75 ± 0.6
Basal Forebrain5.62 ± 0.49
Basal Part of Pons5.55 ± 0.47
Cerebellar Cortex5.34 ± 0.37
Cerebellar Nuclei5.78 ± 0.32
Claustrum5.97 ± 0.84
Epithalamus4.84 ± 0.34
Frontal Lobe5.38 ± 0.49
Globus Pallidus5.96 ± 0.23
Hypothalamus5.51 ± 0.4
Insula5.45 ± 0.5
Limbic Lobe5.7 ± 0.57
Mesencephalon5.81 ± 0.56
Myelencephalon5.6 ± 0.43
Occipital Lobe5.91 ± 0.61
Parietal Lobe5.6 ± 0.49
Pontine Tegmentum5.39 ± 0.53
Striatum5.25 ± 0.71
Subthalamus5.54 ± 0.61
Temporal Lobe5.53 ± 0.45
Thalamus5.5 ± 0.5
White Matter5.55 ± 0.31
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MAST2_HUMAN_1143 10 1143 1152 GGPASEAGLR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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