AutismKB 2.0

Annotation Detail for ZC3H3


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Basic Information Top
Gene Symbol:ZC3H3 ( KIAA0150,ZC3HDC3 )
Gene Full Name: zinc finger CCCH-type containing 3
Band: 8q24.3
Quick LinksEntrez ID:23144; OMIM: NA; Uniprot ID:ZC3H3_HUMAN; ENSEMBL ID: ENSG00000014164; HGNC ID: 28972
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst2 / 6231932
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult25 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor11 / 26384541
glioma6 / 10688356
head and neck tumor5 / 13630236
kidney tumor1 / 6895914
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma2 / 7175527
non-neoplasia0 / 972500 
normal43 / 336030712
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor9 / 12494972
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood6 / 12347848
bone2 / 7165527
bone marrow2 / 4880140
brain8 / 11009897
cervix5 / 48171103
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye8 / 21105437
heart0 / 896260 
intestine4 / 23447217
kidney1 / 2117774
larynx0 / 241450 
liver2 / 2077439
lung5 / 33697414
lymph2 / 4427045
lymph node4 / 9161043
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary5 / 10205148
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate4 / 18934521
salivary gland5 / 20155248
skin9 / 21057442
spleen0 / 539520 
stomach2 / 9661920
testis2 / 3304426
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213445_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.8
Adipocyte3.7
AdrenalCortex3.6
Adrenalgland3.1
Amygdala4
Appendix3.75
AtrioventricularNode2.8
BDCA4+_DentriticCells4.5
Bonemarrow3.65
BronchialEpithelialCells3.6
CD105+_Endothelial3.8
CD14+_Monocytes6.15
CD19+_BCells(neg._sel.)4.1
CD33+_Myeloid6.1
CD34+4.85
CD4+_Tcells4.5
CD56+_NKCells6.6
CD71+_EarlyErythroid3.65
CD8+_Tcells4.05
CardiacMyocytes4.65
Caudatenucleus3.35
Cerebellum3
CerebellumPeduncles4.2
CiliaryGanglion2.55
CingulateCortex3.8
Colorectaladenocarcinoma3.8
DorsalRootGanglion2.75
FetalThyroid3.65
Fetalbrain3.75
Fetalliver3.2
Fetallung3.3
GlobusPallidus2.7
Heart5
Hypothalamus4.05
Kidney3
Leukemia_chronicMyelogenousK-5623.95
Leukemia_promyelocytic-HL-603.3
Leukemialymphoblastic(MOLT-4)3.05
Liver6.2
Lung4.8
Lymphnode3.25
Lymphoma_burkitts(Daudi)4.7
Lymphoma_burkitts(Raji)5.85
MedullaOblongata3.35
OccipitalLobe3.35
OlfactoryBulb2.75
Ovary2.45
Pancreas2.95
PancreaticIslet3.95
ParietalLobe3.85
Pituitary4.35
Placenta4.4
Pons3.5
PrefrontalCortex4.6
Prostate4.45
Salivarygland3.2
SkeletalMuscle4.3
Skin2.8
SmoothMuscle4.2
Spinalcord4
SubthalamicNucleus3.35
SuperiorCervicalGanglion4.15
TemporalLobe3.4
Testis3.25
TestisGermCell5
TestisIntersitial4
TestisLeydigCell4.5
TestisSeminiferousTubule5
Thalamus3.75
Thymus3
Thyroid5.1
Tongue3.6
Tonsil3.6
Trachea3.1
TrigeminalGanglion3.65
Uterus3.1
UterusCorpus3.35
WholeBlood4.15
Wholebrain3.3
colon3.75
pineal_day4.42
pineal_night4.32
retina4.475
small_intestine3.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1558_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.29 ± 0.73
Basal Forebrain4.11 ± 0.49
Basal Part of Pons4.15 ± 0.48
Cerebellar Cortex4.28 ± 0.49
Cerebellar Nuclei4.16 ± 0.58
Claustrum4.43 ± 0.68
Epithalamus3.6 ± 0.68
Frontal Lobe3.86 ± 0.62
Globus Pallidus4.57 ± 0.56
Hypothalamus3.68 ± 0.56
Insula3.74 ± 0.53
Limbic Lobe4.31 ± 0.61
Mesencephalon4.08 ± 0.58
Myelencephalon4.11 ± 0.63
Occipital Lobe4.37 ± 0.7
Parietal Lobe4.19 ± 0.53
Pontine Tegmentum3.98 ± 0.8
Striatum4.06 ± 0.7
Subthalamus3.71 ± 0.49
Temporal Lobe4.14 ± 0.62
Thalamus4.06 ± 0.64
White Matter4.6 ± 0.57
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zc3h3CBCerebellum31.89
41.5
Zc3h3CTXCerebral cortex86.72
66.05
Zc3h3HIPHippocampal region68
95.72
Zc3h3HPFHippocampal formation70.44
81.61
Zc3h3HYHypothalamus9.49
7.26
Zc3h3LSXLateral septal complex9.19
5.6
Zc3h3MBMidbrain12.59
10.91
Zc3h3MYMedulla16.95
17.94
Zc3h3OLFOlfactory bulb70.5
61.7
Zc3h3PPons11.64
11.68
Zc3h3PALPallidum23.28
19.45
Zc3h3RHPRetrohippocampal region75.56
64.35
Zc3h3sAMYStriatum-like amygdalar nuclei47.33
33.77
Zc3h3STRStriatum47.39
33.52
Zc3h3STRdStriatum dorsal region50.84
36.12
Zc3h3STRvStriatum ventral region52.4
35.85
Zc3h3THThalamus28.7
23.39
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ZC3H3_HUMAN_413 29 413 441 SPSGDRPAVGHSGLKPLSGETPLSAYKVK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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