AutismKB 2.0

Annotation Detail for GRAMD4


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:GRAMD4 ( DIP,KIAA0767,MGC149847,MGC90497,dA59H18.1,dJ439F8.1 )
Gene Full Name: GRAM domain containing 4
Band: 22q13.31
Quick LinksEntrez ID:23151; OMIM: NA; Uniprot ID:GRAM4_HUMAN; ENSEMBL ID: ENSG00000075240; HGNC ID: 29113
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus18 / 56401231
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult31 / 193912115
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor10 / 26384537
glioma12 / 106883112
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal74 / 336030722
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor7 / 12494956
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone2 / 7165527
bone marrow0 / 488010 
brain18 / 110098916
cervix1 / 4817120
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye2 / 2110549
heart5 / 8962655
intestine9 / 23447238
kidney14 / 21177766
larynx1 / 2414541
liver0 / 2077430 
lung27 / 33697480
lymph0 / 442700 
lymph node13 / 91610141
mammary gland3 / 15327119
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas6 / 21481227
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate4 / 18934521
salivary gland0 / 201550 
skin9 / 21057442
spleen0 / 539520 
stomach3 / 9661931
testis0 / 3304420 
thymus4 / 8113149
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212856_at
Cell line Expression level Expression bar
721_B_lymphoblasts16.4
Adipocyte11.7
AdrenalCortex49
Adrenalgland27.85
Amygdala32.3
Appendix12.5
AtrioventricularNode9.45
BDCA4+_DentriticCells81.2
Bonemarrow12.55
BronchialEpithelialCells12.85
CD105+_Endothelial13.1
CD14+_Monocytes44.95
CD19+_BCells(neg._sel.)17.85
CD33+_Myeloid84.1
CD34+81.2
CD4+_Tcells12.1
CD56+_NKCells23.4
CD71+_EarlyErythroid11.05
CD8+_Tcells12.65
CardiacMyocytes15.45
Caudatenucleus11.55
Cerebellum10.4
CerebellumPeduncles14.45
CiliaryGanglion8.8
CingulateCortex13.1
Colorectaladenocarcinoma17.15
DorsalRootGanglion9.65
FetalThyroid12.55
Fetalbrain16.6
Fetalliver10.5
Fetallung10.3
GlobusPallidus9.3
Heart20.55
Hypothalamus15.75
Kidney10.3
Leukemia_chronicMyelogenousK-56210.85
Leukemia_promyelocytic-HL-6011.35
Leukemialymphoblastic(MOLT-4)41.35
Liver20.45
Lung66.2
Lymphnode10.4
Lymphoma_burkitts(Daudi)16.95
Lymphoma_burkitts(Raji)18.3
MedullaOblongata10.25
OccipitalLobe11.65
OlfactoryBulb10.2
Ovary8.45
Pancreas10.3
PancreaticIslet25.45
ParietalLobe13.35
Pituitary13.8
Placenta15.45
Pons11.8
PrefrontalCortex18.8
Prostate66.5
Salivarygland10.2
SkeletalMuscle14.4
Skin9.7
SmoothMuscle13.15
Spinalcord14
SubthalamicNucleus9.45
SuperiorCervicalGanglion13.35
TemporalLobe11.65
Testis10.35
TestisGermCell8.85
TestisIntersitial10.25
TestisLeydigCell12.55
TestisSeminiferousTubule9.7
Thalamus12.9
Thymus22.6
Thyroid71.45
Tongue13.7
Tonsil12.55
Trachea10.3
TrigeminalGanglion12.4
Uterus9.15
UterusCorpus11.05
WholeBlood21.4
Wholebrain27.45
colon73.4
pineal_day16.06
pineal_night15.4
retina21.125
small_intestine28.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P91795
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.42 ± 0.26
Basal Forebrain5.22 ± 0.46
Basal Part of Pons4.43 ± 0.42
Cerebellar Cortex4.53 ± 0.41
Cerebellar Nuclei5.69 ± 0.69
Claustrum5.81 ± 0.47
Epithalamus5.19 ± 0.47
Frontal Lobe5.24 ± 0.47
Globus Pallidus5.09 ± 0.67
Hypothalamus4.92 ± 0.58
Insula5.48 ± 0.39
Limbic Lobe5.23 ± 0.41
Mesencephalon5.3 ± 0.58
Myelencephalon5.04 ± 0.59
Occipital Lobe4.71 ± 0.66
Parietal Lobe5.02 ± 0.54
Pontine Tegmentum5.22 ± 0.46
Striatum4.86 ± 0.78
Subthalamus5.87 ± 0.31
Temporal Lobe5.15 ± 0.45
Thalamus4.52 ± 0.5
White Matter3.11 ± 1.6
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
BC021523CBCerebellum9.7
10.22
BC021523CTXCerebral cortex49.91
41.47
BC021523HIPHippocampal region15.4
16.66
BC021523HPFHippocampal formation19.07
18.5
BC021523HYHypothalamus0.63
0.77
BC021523LSXLateral septal complex2.24
1.51
BC021523MBMidbrain3.95
3.83
BC021523MYMedulla3.15
3.08
BC021523OLFOlfactory bulb31.93
26.06
BC021523PPons3.38
3.13
BC021523PALPallidum1.16
1.04
BC021523RHPRetrohippocampal region24.77
20.87
BC021523sAMYStriatum-like amygdalar nuclei5.11
3.9
BC021523STRStriatum2.75
2.39
BC021523STRdStriatum dorsal region2.38
2.4
BC021523STRvStriatum ventral region3.07
1.84
BC021523THThalamus3.05
3.57
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved